Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 3, 2010, Pages 1166-1171

  Pancera, Marie ^a   Majeed, Shahzad ^a   Ban, Yih En Andrew ^b   Chen, Lei ^a   Huang, Chih Chin ^a   Kong, Leopold ^a   Kwon, Young Do ^a   Stuckey, Jonathan ^a   Zhou, Tongqing ^a   Robinson, James E ^c   Schief, William R ^b   Sodroski, Joseph ^d   Wyatt, Richard ^a   Kwong, Peter D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

HIV 1 viral spike; Molecular motion; Protein architecture; Receptortriggered entry; Type 1 fusion protein

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41;

ARTICLE; CELL SURFACE; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; MEMBRANE FUSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 75749133275     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911004107     Document Type: Article

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