-
1
-
-
84942845244
-
Functional genomics bridges the gap between quantitative genetics and molecular biology
-
Lappalainen T. Functional genomics bridges the gap between quantitative genetics and molecular biology. Genome Res 2015, 25:1427-1431. 10.1101/gr.190983.115.
-
(2015)
Genome Res
, vol.25
, pp. 1427-1431
-
-
Lappalainen, T.1
-
2
-
-
84890546613
-
Systems genetics approaches to understand complex traits
-
Civelek M., Lusis A.J. Systems genetics approaches to understand complex traits. Nat Rev Genet 2014, 15:34-48. 10.1038/nrg3575.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 34-48
-
-
Civelek, M.1
Lusis, A.J.2
-
3
-
-
84966692624
-
Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging
-
Labrie V., Buske O.J., Oh E., Jeremian R., Ptak C., Gasiunas G., Maleckas A., Petereit R., Zvirbliene A., Adamonis K., et al. Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging. Nat Struct Mol Biol 2016, 23:566-573.
-
(2016)
Nat Struct Mol Biol
, vol.23
, pp. 566-573
-
-
Labrie, V.1
Buske, O.J.2
Oh, E.3
Jeremian, R.4
Ptak, C.5
Gasiunas, G.6
Maleckas, A.7
Petereit, R.8
Zvirbliene, A.9
Adamonis, K.10
-
4
-
-
84940830979
-
FTO obesity variant circuitry and adipocyte browning in humans
-
Claussnitzer M., Dankel S.N., Kim K.-H., Quon G., Meuleman W., Haugen C., Glunk V., Sousa I.S., Beaudry J.L., Puviindran V., et al. FTO obesity variant circuitry and adipocyte browning in humans. N Engl J Med 2015, 373:895-907. 10.1056/NEJMoa1502214.
-
(2015)
N Engl J Med
, vol.373
, pp. 895-907
-
-
Claussnitzer, M.1
Dankel, S.N.2
Kim, K.-H.3
Quon, G.4
Meuleman, W.5
Haugen, C.6
Glunk, V.7
Sousa, I.S.8
Beaudry, J.L.9
Puviindran, V.10
-
5
-
-
45149106353
-
Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks
-
Zhu J., Zhang B., Smith E.N., Drees B., Brem R.B., Kruglyak L., Bumgarner R.E., Schadt E.E. Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nat Genet 2008, 40:854-861. 10.1038/ng.167.
-
(2008)
Nat Genet
, vol.40
, pp. 854-861
-
-
Zhu, J.1
Zhang, B.2
Smith, E.N.3
Drees, B.4
Brem, R.B.5
Kruglyak, L.6
Bumgarner, R.E.7
Schadt, E.E.8
-
6
-
-
84979523711
-
Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine
-
Petrovski S., Goldstein D.B. Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine. Genome Biol 2016, 17:157. 10.1186/s13059-016-1016-y.
-
(2016)
Genome Biol
, vol.17
, pp. 157
-
-
Petrovski, S.1
Goldstein, D.B.2
-
7
-
-
84982187833
-
Genetic misdiagnoses and the potential for health disparities
-
Manrai A.K., Funke B.H., Rehm H.L., Olesen M.S., Maron B.A., Szolovits P., Margulies D.M., Loscalzo J., Kohane I.S. Genetic misdiagnoses and the potential for health disparities. N Engl J Med 2016, 375:655-665. 10.1056/NEJMsa1507092.
-
(2016)
N Engl J Med
, vol.375
, pp. 655-665
-
-
Manrai, A.K.1
Funke, B.H.2
Rehm, H.L.3
Olesen, M.S.4
Maron, B.A.5
Szolovits, P.6
Margulies, D.M.7
Loscalzo, J.8
Kohane, I.S.9
-
8
-
-
84994236541
-
Inferences of African evolutionary history from genomic data
-
Beltrame M.H., Rubel M.A., Tishkoff S.A. Inferences of African evolutionary history from genomic data. Genet Hum Orig 2016, 41:159-166. 10.1016/j.gde.2016.10.002.
-
(2016)
Genet Hum Orig
, vol.41
, pp. 159-166
-
-
Beltrame, M.H.1
Rubel, M.A.2
Tishkoff, S.A.3
-
9
-
-
0037147189
-
Genetic structure of human populations
-
Rosenberg N.A., Pritchard J.K., Weber J.L., Cann H.M., Kidd K.K., Zhivotovsky L.A., Feldman M.W. Genetic structure of human populations. Science 2002, 298:2381-2385. 10.1126/science.1078311.
-
(2002)
Science
, vol.298
, pp. 2381-2385
-
-
Rosenberg, N.A.1
Pritchard, J.K.2
Weber, J.L.3
Cann, H.M.4
Kidd, K.K.5
Zhivotovsky, L.A.6
Feldman, M.W.7
-
10
-
-
27644509150
-
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa
-
Ramachandran S., Deshpande O., Roseman C.C., Rosenberg N.A., Feldman M.W., Cavalli-Sforza L.L. Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A 2005, 102:15942-15947. 10.1073/pnas.0507611102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15942-15947
-
-
Ramachandran, S.1
Deshpande, O.2
Roseman, C.C.3
Rosenberg, N.A.4
Feldman, M.W.5
Cavalli-Sforza, L.L.6
-
11
-
-
66249116333
-
The genetic structure and history of Africans and African Americans
-
Tishkoff S.A., Reed F.A., Friedlaender F.R., Ehret C., Ranciaro A., Froment A., Hirbo J.B., Awomoyi A.A., Bodo J.-M., Doumbo O., et al. The genetic structure and history of Africans and African Americans. Science 2009, 324:1035-1044. 10.1126/science.1172257.
-
(2009)
Science
, vol.324
, pp. 1035-1044
-
-
Tishkoff, S.A.1
Reed, F.A.2
Friedlaender, F.R.3
Ehret, C.4
Ranciaro, A.5
Froment, A.6
Hirbo, J.B.7
Awomoyi, A.A.8
Bodo, J.-M.9
Doumbo, O.10
-
12
-
-
84973317674
-
Ancient DNA and human history
-
Slatkin M., Racimo F. Ancient DNA and human history. Proc Natl Acad Sci 2016, 113:6380-6387. 10.1073/pnas.1524306113.
-
(2016)
Proc Natl Acad Sci
, vol.113
, pp. 6380-6387
-
-
Slatkin, M.1
Racimo, F.2
-
13
-
-
38749131273
-
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture
-
Enattah N.S., Jensen T.G., Nielsen M., Lewinski R., Kuokkanen M., Rasinpera H., El-Shanti H., Seo J.K., Alifrangis M., Khalil I.F., et al. Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture. Am J Hum Genet 2008, 82:57-72. 10.1016/j.ajhg.2007.09.012.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 57-72
-
-
Enattah, N.S.1
Jensen, T.G.2
Nielsen, M.3
Lewinski, R.4
Kuokkanen, M.5
Rasinpera, H.6
El-Shanti, H.7
Seo, J.K.8
Alifrangis, M.9
Khalil, I.F.10
-
14
-
-
33845900450
-
Convergent adaptation of human lactase persistence in Africa and Europe
-
Tishkoff S.A., Reed F.A., Ranciaro A., Voight B.F., Babbitt C.C., Silverman J.S., Powell K., Mortensen H.M., Hirbo J.B., Osman M., et al. Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet 2007, 39:31-40. 10.1038/ng1946.
-
(2007)
Nat Genet
, vol.39
, pp. 31-40
-
-
Tishkoff, S.A.1
Reed, F.A.2
Ranciaro, A.3
Voight, B.F.4
Babbitt, C.C.5
Silverman, J.S.6
Powell, K.7
Mortensen, H.M.8
Hirbo, J.B.9
Osman, M.10
-
15
-
-
84897979695
-
Genetic origins of lactase persistence and the spread of pastoralism in Africa
-
Ranciaro A., Campbell M.C., Hirbo J.B., Ko W.-Y., Froment A., Anagnostou P., Kotze M.J., Ibrahim M., Nyambo T., Omar S.A., Tishkoff S.A. Genetic origins of lactase persistence and the spread of pastoralism in Africa. Am J Hum Genet 2014, 94:496-510. 10.1016/j.ajhg.2014.02.009.
-
(2014)
Am J Hum Genet
, vol.94
, pp. 496-510
-
-
Ranciaro, A.1
Campbell, M.C.2
Hirbo, J.B.3
Ko, W.-Y.4
Froment, A.5
Anagnostou, P.6
Kotze, M.J.7
Ibrahim, M.8
Nyambo, T.9
Omar, S.A.10
Tishkoff, S.A.11
-
16
-
-
84922296279
-
Transcriptome sequencing from diverse human populations reveals differentiated regulatory architecture
-
Martin A.R., Costa H.A., Lappalainen T., Henn B.M., Kidd J.M., Yee M.-C., Grubert F., Cann H.M., Snyder M., Montgomery S.B., Bustamante C.D. Transcriptome sequencing from diverse human populations reveals differentiated regulatory architecture. PLoS Genet 2014, 10:e1004549. 10.1371/journal.pgen.1004549.
-
(2014)
PLoS Genet
, vol.10
-
-
Martin, A.R.1
Costa, H.A.2
Lappalainen, T.3
Henn, B.M.4
Kidd, J.M.5
Yee, M.-C.6
Grubert, F.7
Cann, H.M.8
Snyder, M.9
Montgomery, S.B.10
Bustamante, C.D.11
-
17
-
-
84860596557
-
Patterns of cis regulatory variation in diverse human populations
-
Stranger B.E., Montgomery S.B., Dimas A.S., Parts L., Stegle O., Ingle C.E., Sekowska M., Smith G.D., Evans D., Gutierrez-Arcelus M., et al. Patterns of cis regulatory variation in diverse human populations. PLoS Genet 2012, 8:e1002639. 10.1371/journal.pgen.1002639.
-
(2012)
PLoS Genet
, vol.8
-
-
Stranger, B.E.1
Montgomery, S.B.2
Dimas, A.S.3
Parts, L.4
Stegle, O.5
Ingle, C.E.6
Sekowska, M.7
Smith, G.D.8
Evans, D.9
Gutierrez-Arcelus, M.10
-
18
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen T., Sammeth M., Friedländer M.R., 't Hoen P.A., Monlong J., Rivas M.A., Gonzàlez-Porta M., Kurbatova N., Griebel T., Ferreira P.G., et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 2013, 501:506-511. 10.1038/nature12531.
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
Sammeth, M.2
Friedländer, M.R.3
't Hoen, P.A.4
Monlong, J.5
Rivas, M.A.6
Gonzàlez-Porta, M.7
Kurbatova, N.8
Griebel, T.9
Ferreira, P.G.10
-
19
-
-
84968935141
-
Worldwide patterns of human epigenetic variation
-
Carja O., MacIsaac J.L., Mah S.M., Henn B.M., Kobor M.S., Feldman M.W., Fraser H.B. Worldwide patterns of human epigenetic variation. bioRxiv 2015, 10.1101/021931.
-
(2015)
bioRxiv
-
-
Carja, O.1
MacIsaac, J.L.2
Mah, S.M.3
Henn, B.M.4
Kobor, M.S.5
Feldman, M.W.6
Fraser, H.B.7
-
20
-
-
84954270790
-
Analysis of genome-wide RNA-sequencing data suggests age of the CEPH/Utah (CEU) lymphoblastoid cell lines systematically biases gene expression profiles
-
Yuan Y., Tian L., Lu D., Xu S. Analysis of genome-wide RNA-sequencing data suggests age of the CEPH/Utah (CEU) lymphoblastoid cell lines systematically biases gene expression profiles. Sci Rep 2015, 5:7960. 10.1038/srep07960.
-
(2015)
Sci Rep
, vol.5
, pp. 7960
-
-
Yuan, Y.1
Tian, L.2
Lu, D.3
Xu, S.4
-
21
-
-
84907000985
-
The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines
-
Çalişkan M., Pritchard J.K., Ober C., Gilad Y. The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines. PLoS One 2014, 9:e107166. 10.1371/journal.pone.0107166.
-
(2014)
PLoS One
, vol.9
-
-
Çalişkan, M.1
Pritchard, J.K.2
Ober, C.3
Gilad, Y.4
-
22
-
-
34347326155
-
On the design and analysis of gene expression studies in human populations
-
Akey J.M., Biswas S., Leek J.T., Storey J.D. On the design and analysis of gene expression studies in human populations. Nat Genet 2007, 39:807-808. 10.1038/ng0707-807.
-
(2007)
Nat Genet
, vol.39
, pp. 807-808
-
-
Akey, J.M.1
Biswas, S.2
Leek, J.T.3
Storey, J.D.4
-
23
-
-
84930636749
-
Evaluating intra- and inter-individual variation in the human placental transcriptome
-
Hughes D.A., Kircher M., He Z., Guo S., Fairbrother G.L., Moreno C.S., Khaitovich P., Stoneking M. Evaluating intra- and inter-individual variation in the human placental transcriptome. Genome Biol 2015, 16:54. 10.1186/s13059-015-0627-z.
-
(2015)
Genome Biol
, vol.16
, pp. 54
-
-
Hughes, D.A.1
Kircher, M.2
He, Z.3
Guo, S.4
Fairbrother, G.L.5
Moreno, C.S.6
Khaitovich, P.7
Stoneking, M.8
-
24
-
-
84901014110
-
Natural selection and infectious disease in human populations
-
Karlsson E.K., Kwiatkowski D.P., Sabeti P.C. Natural selection and infectious disease in human populations. Nat Rev Genet 2014, 15:379-393. 10.1038/nrg3734.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 379-393
-
-
Karlsson, E.K.1
Kwiatkowski, D.P.2
Sabeti, P.C.3
-
25
-
-
84990857358
-
Going global by adapting local: a review of recent human adaptation
-
Fan S., Hansen M.E.B., Lo Y., Tishkoff S.A. Going global by adapting local: a review of recent human adaptation. Science 2016, 354:54-59. 10.1126/science.aaf5098.
-
(2016)
Science
, vol.354
, pp. 54-59
-
-
Fan, S.1
Hansen, M.E.B.2
Lo, Y.3
Tishkoff, S.A.4
-
26
-
-
84925089678
-
The role of regulatory variation in complex traits and disease
-
Albert F.W., Kruglyak L. The role of regulatory variation in complex traits and disease. Nat Rev Genet 2015, 16:197-212.
-
(2015)
Nat Rev Genet
, vol.16
, pp. 197-212
-
-
Albert, F.W.1
Kruglyak, L.2
-
27
-
-
84966470585
-
Genetic sources of population epigenomic variation
-
Taudt A., Colome-Tatche M., Johannes F. Genetic sources of population epigenomic variation. Nat Rev Genet 2016, 17:319-332.
-
(2016)
Nat Rev Genet
, vol.17
, pp. 319-332
-
-
Taudt, A.1
Colome-Tatche, M.2
Johannes, F.3
-
28
-
-
84856791176
-
Population-specificity of human DNA methylation
-
Fraser H.B., Lam L.L., Neumann S.M., Kobor M.S. Population-specificity of human DNA methylation. Genome Biol 2012, 13. R8-R8. 10.1186/gb-2012-13-2-r8.
-
(2012)
Genome Biol
, vol.13
, pp. R8-R8
-
-
Fraser, H.B.1
Lam, L.L.2
Neumann, S.M.3
Kobor, M.S.4
-
29
-
-
84948800040
-
The epigenomic landscape of African rainforest hunter-gatherers and farmers
-
Fagny M., Patin E., MacIsaac J.L., Rotival M., Flutre T., Jones M.J., Siddle K.J., Quach H., Harmant C., McEwen L.M., et al. The epigenomic landscape of African rainforest hunter-gatherers and farmers. Nat Commun 2015, 6:10047. 10.1038/ncomms10047.
-
(2015)
Nat Commun
, vol.6
, pp. 10047
-
-
Fagny, M.1
Patin, E.2
MacIsaac, J.L.3
Rotival, M.4
Flutre, T.5
Jones, M.J.6
Siddle, K.J.7
Quach, H.8
Harmant, C.9
McEwen, L.M.10
-
30
-
-
84887320760
-
Extensive variation in chromatin states across humans
-
Kasowski M., Kyriazopoulou-Panagiotopoulou S., Grubert F., Zaugg J.B., Kundaje A., Liu Y., Boyle A.P., Zhang Q.C., Zakharia F., Spacek D.V., et al. Extensive variation in chromatin states across humans. Science 2013, 342:750-752. 10.1126/science.1242510.
-
(2013)
Science
, vol.342
, pp. 750-752
-
-
Kasowski, M.1
Kyriazopoulou-Panagiotopoulou, S.2
Grubert, F.3
Zaugg, J.B.4
Kundaje, A.5
Liu, Y.6
Boyle, A.P.7
Zhang, Q.C.8
Zakharia, F.9
Spacek, D.V.10
-
31
-
-
73349126396
-
Geographical genomics of human leukocyte gene expression variation in southern Morocco
-
Idaghdour Y., Czika W., Shianna K.V., Lee S.H., Visscher P.M., Martin H.C., Miclaus K., Jadallah S.J., Goldstein D.B., Wolfinger R.D., Gibson G. Geographical genomics of human leukocyte gene expression variation in southern Morocco. Nat Genet 2010, 42:62-67. 10.1038/ng.495.
-
(2010)
Nat Genet
, vol.42
, pp. 62-67
-
-
Idaghdour, Y.1
Czika, W.2
Shianna, K.V.3
Lee, S.H.4
Visscher, P.M.5
Martin, H.C.6
Miclaus, K.7
Jadallah, S.J.8
Goldstein, D.B.9
Wolfinger, R.D.10
Gibson, G.11
-
32
-
-
84900338300
-
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes
-
Raj T., Rothamel K., Mostafavi S., Ye C., Lee M.N., Replogle J.M., Feng T., Lee M., Asinovski N., Frohlich I., et al. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science 2014, 344:519-523. 10.1126/science.1249547.
-
(2014)
Science
, vol.344
, pp. 519-523
-
-
Raj, T.1
Rothamel, K.2
Mostafavi, S.3
Ye, C.4
Lee, M.N.5
Replogle, J.M.6
Feng, T.7
Lee, M.8
Asinovski, N.9
Frohlich, I.10
-
33
-
-
84896759364
-
Common genetic variants modulate pathogen-sensing responses in human dendritic cells
-
1246980-1246980.
-
Lee M.N., Ye C., Villani A.-C., Raj T., Li W., Eisenhaure T.M., Imboywa S.H., Chipendo P.I., Ran F.A., Slowikowski K., et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science 2014, 343. 1246980-1246980. 10.1126/science.1246980.
-
(2014)
Science
, vol.343
-
-
Lee, M.N.1
Ye, C.2
Villani, A.-C.3
Raj, T.4
Li, W.5
Eisenhaure, T.M.6
Imboywa, S.H.7
Chipendo, P.I.8
Ran, F.A.9
Slowikowski, K.10
-
34
-
-
84907202723
-
Intersection of population variation and autoimmunity genetics in human T cell activation
-
1254665-1254665.
-
Ye C.J., Feng T., Kwon H.-K., Raj T., Wilson M., Asinovski N., McCabe C., Lee M.H., Frohlich I., Paik H., et al. Intersection of population variation and autoimmunity genetics in human T cell activation. Science 2014, 345. 1254665-1254665. 10.1126/science.1254665.
-
(2014)
Science
, vol.345
-
-
Ye, C.J.1
Feng, T.2
Kwon, H.-K.3
Raj, T.4
Wilson, M.5
Asinovski, N.6
McCabe, C.7
Lee, M.H.8
Frohlich, I.9
Paik, H.10
-
35
-
-
84992187388
-
Genetic adaptation and neandertal admixture shaped the immune system of human populations
-
Quach H., Rotival M., Pothlichet J., Loh Y.-H.E., Dannemann M., Zidane N., Laval G., Patin E., Harmant C., Lopez M., et al. Genetic adaptation and neandertal admixture shaped the immune system of human populations. Cell 2016, 167:643-656.e17. 10.1016/j.cell.2016.09.024.
-
(2016)
Cell
, vol.167
, pp. 643-656.e17
-
-
Quach, H.1
Rotival, M.2
Pothlichet, J.3
Loh, Y.-H.E.4
Dannemann, M.5
Zidane, N.6
Laval, G.7
Patin, E.8
Harmant, C.9
Lopez, M.10
-
36
-
-
84992381901
-
Genetic ancestry and natural selection drive population differences in immune responses to pathogens
-
Nédélec Y., Sanz J., Baharian G., Szpiech Z.A., Pacis A., Dumaine A., Grenier J.-C., Freiman A., Sams A.J., Hebert S., et al. Genetic ancestry and natural selection drive population differences in immune responses to pathogens. Cell 2016, 167:657-669. 10.1016/j.cell.2016.09.025.
-
(2016)
Cell
, vol.167
, pp. 657-669
-
-
Nédélec, Y.1
Sanz, J.2
Baharian, G.3
Szpiech, Z.A.4
Pacis, A.5
Dumaine, A.6
Grenier, J.-C.7
Freiman, A.8
Sams, A.J.9
Hebert, S.10
-
38
-
-
84968732934
-
RNA splicing is a primary link between genetic variation and disease
-
Li Y.I., van de Geijn B., Raj A., Knowles D.A., Petti A.A., Golan D., Gilad Y., Pritchard J.K. RNA splicing is a primary link between genetic variation and disease. Science 2016, 352:600-604. 10.1126/science.aad9417.
-
(2016)
Science
, vol.352
, pp. 600-604
-
-
Li, Y.I.1
van de Geijn, B.2
Raj, A.3
Knowles, D.A.4
Petti, A.A.5
Golan, D.6
Gilad, Y.7
Pritchard, J.K.8
-
39
-
-
84976498063
-
A survey of the sorghum transcriptome using single-molecule long reads
-
Abdel-Ghany S.E., Hamilton M., Jacobi J.L., Ngam P., Devitt N., Schilkey F., Ben-Hur A., Reddy A.S.N. A survey of the sorghum transcriptome using single-molecule long reads. Nat Commun 2016, 7:11706. 10.1038/ncomms11706.
-
(2016)
Nat Commun
, vol.7
, pp. 11706
-
-
Abdel-Ghany, S.E.1
Hamilton, M.2
Jacobi, J.L.3
Ngam, P.4
Devitt, N.5
Schilkey, F.6
Ben-Hur, A.7
Reddy, A.S.N.8
-
40
-
-
84962544731
-
A new view of transcriptome complexity and regulation through the lens of local splicing variations
-
Vaquero-Garcia J., Barrera A., Gazzara M.R., González-Vallinas J., Lahens N.F., Hogenesch J.B., Lynch K.W., Barash Y. A new view of transcriptome complexity and regulation through the lens of local splicing variations. eLife 2016, 5:e11752. 10.7554/eLife.11752.
-
(2016)
eLife
, vol.5
-
-
Vaquero-Garcia, J.1
Barrera, A.2
Gazzara, M.R.3
González-Vallinas, J.4
Lahens, N.F.5
Hogenesch, J.B.6
Lynch, K.W.7
Barash, Y.8
-
41
-
-
85028165246
-
Ten years of next-generation sequencing technology
-
van Dijk E.L., Auger H., Jaszczyszyn Y., Thermes C. Ten years of next-generation sequencing technology. Trends Genet 2014, 30:418-426. 10.1016/j.tig.2014.07.001.
-
(2014)
Trends Genet
, vol.30
, pp. 418-426
-
-
van Dijk, E.L.1
Auger, H.2
Jaszczyszyn, Y.3
Thermes, C.4
-
42
-
-
84955439663
-
A survey of best practices for RNA-seq data analysis
-
Conesa A., Madrigal P., Tarazona S., Gomez-Cabrero D., Cervera A., McPherson A., Szcześniak M.W., Gaffney D.J., Elo L.L., Zhang X., Mortazavi A. A survey of best practices for RNA-seq data analysis. Genome Biol 2016, 17:13. 10.1186/s13059-016-0881-8.
-
(2016)
Genome Biol
, vol.17
, pp. 13
-
-
Conesa, A.1
Madrigal, P.2
Tarazona, S.3
Gomez-Cabrero, D.4
Cervera, A.5
McPherson, A.6
Szcześniak, M.W.7
Gaffney, D.J.8
Elo, L.L.9
Zhang, X.10
Mortazavi, A.11
-
43
-
-
84922469439
-
Impact of regulatory variation from RNA to protein
-
Battle A., Khan Z., Wang S.H., Mitrano A., Ford M.J., Pritchard J.K., Gilad Y. Impact of regulatory variation from RNA to protein. Science 2015, 347:664-667. 10.1126/science.1260793.
-
(2015)
Science
, vol.347
, pp. 664-667
-
-
Battle, A.1
Khan, Z.2
Wang, S.H.3
Mitrano, A.4
Ford, M.J.5
Pritchard, J.K.6
Gilad, Y.7
-
44
-
-
84946571937
-
Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans
-
Cenik C., Cenik E.S., Byeon G.W., Grubert F., Candille S.I., Spacek D., Alsallakh B., Tilgner H., Araya C.L., Tang H., et al. Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans. Genome Res 2015, 25:1610-1621. 10.1101/gr.193342.115.
-
(2015)
Genome Res
, vol.25
, pp. 1610-1621
-
-
Cenik, C.1
Cenik, E.S.2
Byeon, G.W.3
Grubert, F.4
Candille, S.I.5
Spacek, D.6
Alsallakh, B.7
Tilgner, H.8
Araya, C.L.9
Tang, H.10
-
45
-
-
84945497191
-
Ribosome profiling reveals the what, when, where and how of protein synthesis
-
Brar G.A., Weissman J.S. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol 2015, 16:651-664.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 651-664
-
-
Brar, G.A.1
Weissman, J.S.2
-
46
-
-
84969780844
-
Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity
-
Sajuthi S.P., Sharma N.K., Chou J.W., Palmer N.D., McWilliams D.R., Beal J., Comeau M.E., Ma L., Calles-Escandon J., Demons J., et al. Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity. Hum Genet 2016, 135:869-880. 10.1007/s00439-016-1680-8.
-
(2016)
Hum Genet
, vol.135
, pp. 869-880
-
-
Sajuthi, S.P.1
Sharma, N.K.2
Chou, J.W.3
Palmer, N.D.4
McWilliams, D.R.5
Beal, J.6
Comeau, M.E.7
Ma, L.8
Calles-Escandon, J.9
Demons, J.10
-
47
-
-
84929001104
-
The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans
-
Ardlie K.G., Deluca D.S., Segrè A.V., Sullivan T.J., Young T.R., Gelfand E.T., Trowbridge C.A., Maller J.B., Tukiainen T., Lek M., et al. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 2015, 348:648-660. 10.1126/science.1262110.
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
Ardlie, K.G.1
Deluca, D.S.2
Segrè, A.V.3
Sullivan, T.J.4
Young, T.R.5
Gelfand, E.T.6
Trowbridge, C.A.7
Maller, J.B.8
Tukiainen, T.9
Lek, M.10
-
48
-
-
85014118986
-
Local genetic effects on gene expression across 44 human tissues
-
Aguet F., Brown A.A., Castel S., Davis J.R., Mohammadi P., Segre A.V., Zappala Z., Abell N.S., Fresard L., Gamazon E.R., et al. Local genetic effects on gene expression across 44 human tissues. bioRxiv 2016, 10.1101/074450.
-
(2016)
bioRxiv
-
-
Aguet, F.1
Brown, A.A.2
Castel, S.3
Davis, J.R.4
Mohammadi, P.5
Segre, A.V.6
Zappala, Z.7
Abell, N.S.8
Fresard, L.9
Gamazon, E.R.10
-
49
-
-
85029951523
-
Integrating tissue specific mechanisms into GWAS summary results
-
Barbeira A., Dickinson S.P., Torres J.M., Torstenson E.S., Zheng J., Wheeler H.E., Shah K.P., Edwards T., Nicolae D., Cox N.J., Im H.K. Integrating tissue specific mechanisms into GWAS summary results. bioRxiv 2016, 10.1101/045260.
-
(2016)
bioRxiv
-
-
Barbeira, A.1
Dickinson, S.P.2
Torres, J.M.3
Torstenson, E.S.4
Zheng, J.5
Wheeler, H.E.6
Shah, K.P.7
Edwards, T.8
Nicolae, D.9
Cox, N.J.10
Im, H.K.11
-
50
-
-
85045336594
-
Estimating the causal tissues for complex traits and diseases
-
Ongen H., Brown A.A., Delaneau O., Panousis N., Nica A.C., Dermitzakis E.T. Estimating the causal tissues for complex traits and diseases. bioRxiv 2016, 10.1101/074682.
-
(2016)
bioRxiv
-
-
Ongen, H.1
Brown, A.A.2
Delaneau, O.3
Panousis, N.4
Nica, A.C.5
Dermitzakis, E.T.6
-
51
-
-
84959536508
-
Pluripotent stem cells in disease modelling and drug discovery
-
Avior Y., Sagi I., Benvenisty N. Pluripotent stem cells in disease modelling and drug discovery. Nat Rev Mol Cell Biol 2016, 17:170-182.
-
(2016)
Nat Rev Mol Cell Biol
, vol.17
, pp. 170-182
-
-
Avior, Y.1
Sagi, I.2
Benvenisty, N.3
-
52
-
-
84958730029
-
Genetic variation, not cell type of origin, underlies the majority of identifiable regulatory differences in iPSCs
-
Burrows C.K., Banovich N.E., Pavlovic B.J., Patterson K., Gallego Romero I., Pritchard J.K., Gilad Y. Genetic variation, not cell type of origin, underlies the majority of identifiable regulatory differences in iPSCs. PLoS Genet 2016, 12:e1005793. 10.1371/journal.pgen.1005793.
-
(2016)
PLoS Genet
, vol.12
-
-
Burrows, C.K.1
Banovich, N.E.2
Pavlovic, B.J.3
Patterson, K.4
Gallego Romero, I.5
Pritchard, J.K.6
Gilad, Y.7
-
53
-
-
85017178591
-
Common genetic variation drives molecular heterogeneity in human iPSCs
-
Kilpinen H., Goncalves A., Leha A., Afzal V., Ashford S., Bala S., Bensaddek D., Casale F.P., Culley O., Danacek P., et al. Common genetic variation drives molecular heterogeneity in human iPSCs. bioRxiv 2016, 10.1101/055160.
-
(2016)
bioRxiv
-
-
Kilpinen, H.1
Goncalves, A.2
Leha, A.3
Afzal, V.4
Ashford, S.5
Bala, S.6
Bensaddek, D.7
Casale, F.P.8
Culley, O.9
Danacek, P.10
-
55
-
-
84930715906
-
Human adaptation to arsenic-rich environments
-
Schlebusch C.M., Gattepaille L.M., Engström K., Vahter M., Jakobsson M., Broberg K. Human adaptation to arsenic-rich environments. Mol Biol Evol 2015, 32:1544-1555. 10.1093/molbev/msv046.
-
(2015)
Mol Biol Evol
, vol.32
, pp. 1544-1555
-
-
Schlebusch, C.M.1
Gattepaille, L.M.2
Engström, K.3
Vahter, M.4
Jakobsson, M.5
Broberg, K.6
-
56
-
-
33846631884
-
Common genetic variants account for differences in gene expression among ethnic groups
-
Spielman R.S., Bastone L.A., Burdick J.T., Morley M., Ewens W.J., Cheung V.G. Common genetic variants account for differences in gene expression among ethnic groups. Nat Genet 2007, 39:226-231. 10.1038/ng1955.
-
(2007)
Nat Genet
, vol.39
, pp. 226-231
-
-
Spielman, R.S.1
Bastone, L.A.2
Burdick, J.T.3
Morley, M.4
Ewens, W.J.5
Cheung, V.G.6
-
57
-
-
33847181678
-
Gene-expression variation within and among human populations
-
Storey J.D., Madeoy J., Strout J.L., Wurfel M., Ronald J., Akey J.M. Gene-expression variation within and among human populations. Am J Hum Genet 2007, 80:502-509.
-
(2007)
Am J Hum Genet
, vol.80
, pp. 502-509
-
-
Storey, J.D.1
Madeoy, J.2
Strout, J.L.3
Wurfel, M.4
Ronald, J.5
Akey, J.M.6
-
58
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
Stranger B.E., Forrest M.S., Dunning M., Ingle C.E., Beazley C., Thorne N., Redon R., Bird C.P., de Grassi A., Lee C., et al. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 2007, 315:848-853. 10.1126/science.1136678.
-
(2007)
Science
, vol.315
, pp. 848-853
-
-
Stranger, B.E.1
Forrest, M.S.2
Dunning, M.3
Ingle, C.E.4
Beazley, C.5
Thorne, N.6
Redon, R.7
Bird, C.P.8
de Grassi, A.9
Lee, C.10
-
59
-
-
77950833803
-
Variation in transcription factor binding among humans
-
Kasowski M., Grubert F., Heffelfinger C., Hariharan M., Asabere A., Waszak S.M., Habegger L., Rozowsky J., Shi M., Urban A.E., et al. Variation in transcription factor binding among humans. Science 2010, 328:232-235. 10.1126/science.1183621.
-
(2010)
Science
, vol.328
, pp. 232-235
-
-
Kasowski, M.1
Grubert, F.2
Heffelfinger, C.3
Hariharan, M.4
Asabere, A.5
Waszak, S.M.6
Habegger, L.7
Rozowsky, J.8
Shi, M.9
Urban, A.E.10
-
60
-
-
84879879014
-
Variation and genetic control of protein abundance in humans
-
Wu L., Candille S.I., Choi Y., Xie D., Li-Pook-Than J., Tang H., Snyder M. Variation and genetic control of protein abundance in humans. Nature 2013, 499:79-82. 10.1038/nature12223.
-
(2013)
Nature
, vol.499
, pp. 79-82
-
-
Wu, L.1
Candille, S.I.2
Choi, Y.3
Xie, D.4
Li-Pook-Than, J.5
Tang, H.6
Snyder, M.7
|