메뉴 건너뛰기




Volumn 25, Issue 10, 2015, Pages 1427-1431

Functional genomics bridges the gap between quantitative genetics and molecular biology

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONAL GENOMICS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN GENETICS; HUMAN GENOME; MOLECULAR BIOLOGY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; QUANTITATIVE GENETICS; QUANTITATIVE TRAIT LOCUS; REGULATORY MECHANISM; REVIEW; FORECASTING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOMICS; REGULATORY SEQUENCE; TRENDS;

EID: 84942845244     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.190983.115     Document Type: Review
Times cited : (45)

References (56)
  • 1
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • The 1000 Genomes Project Consortium. 2012. An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56-65.
    • (2012) Nature , vol.491 , pp. 56-65
  • 2
    • 84925089678 scopus 로고    scopus 로고
    • The role of regulatory variation in complex traits and disease
    • Albert FW, Kruglyak L. 2015. The role of regulatory variation in complex traits and disease. Nat Rev Genet 16: 197-212.
    • (2015) Nat Rev Genet , vol.16 , pp. 197-212
    • Albert, F.W.1    Kruglyak, L.2
  • 3
    • 84874381107 scopus 로고    scopus 로고
    • Genomewide quantitative enhancer activity maps identified by STARR-seq
    • Arnold CD, Gerlach D, Stelzer C, Boryn LM, Rath M, Stark A. 2013. Genomewide quantitative enhancer activity maps identified by STARR-seq. Science 339: 1074-1077.
    • (2013) Science , vol.339 , pp. 1074-1077
    • Arnold, C.D.1    Gerlach, D.2    Stelzer, C.3    Boryn, L.M.4    Rath, M.5    Stark, A.6
  • 11
    • 27644482314 scopus 로고    scopus 로고
    • Mapping determinants of human gene expression by regional and genome-wide association
    • Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT. 2005. Mapping determinants of human gene expression by regional and genome-wide association. Nature 437: 1365-1369.
    • (2005) Nature , vol.437 , pp. 1365-1369
    • Cheung, V.G.1    Spielman, R.S.2    Ewens, K.G.3    Weber, T.M.4    Morley, M.5    Burdick, J.T.6
  • 14
    • 84913594397 scopus 로고    scopus 로고
    • Genome editing. The new frontier of genome engineering with CRISPR-Cas9
    • Doudna JA, Charpentier E. 2014. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346: 1258096.
    • (2014) Science , vol.346 , pp. 1258096
    • Doudna, J.A.1    Charpentier, E.2
  • 16
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • The ENCODE Project Consortium. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489: 57-74.
    • (2012) Nature , vol.489 , pp. 57-74
  • 17
    • 84897406127 scopus 로고    scopus 로고
    • A promoter-level mammalian expression atlas
    • The FANTOM Consortium and the RIKEN PMI and CLST (DGT). 2014. A promoter-level mammalian expression atlas. Nature 507: 462-470.
    • (2014) Nature , vol.507 , pp. 462-470
  • 19
    • 84907257107 scopus 로고    scopus 로고
    • Saturation editing of genomic regions by multiplex homology-directed repair
    • Findlay GM, Boyle EA, Hause RJ, Klein JC, Shendure J. 2014. Saturation editing of genomic regions by multiplex homology-directed repair. Nature 513: 120-123.
    • (2014) Nature , vol.513 , pp. 120-123
    • Findlay, G.M.1    Boyle, E.A.2    Hause, R.J.3    Klein, J.C.4    Shendure, J.5
  • 20
    • 84880076219 scopus 로고    scopus 로고
    • Gene expression drives local adaptation in humans
    • Fraser HB. 2013. Gene expression drives local adaptation in humans. Genome Res 23: 1089-1096.
    • (2013) Genome Res , vol.23 , pp. 1089-1096
    • Fraser, H.B.1
  • 26
    • 84878682420 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) project
    • GTEx Consortium. 2013. The Genotype-Tissue Expression (GTEx) project. Nat Genet 45: 580-585.
    • (2013) Nat Genet , vol.45 , pp. 580-585
  • 27
    • 84929001104 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) pilot analysis of multi-tissue gene regulation in humans
    • GTEx Consortium. 2015. The Genotype-Tissue Expression (GTEx) pilot analysis of multi-tissue gene regulation in humans. Science 348: 648-660.
    • (2015) Science , vol.348 , pp. 648-660
  • 31
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • The International HapMap Consortium. 2007. A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-861.
    • (2007) Nature , vol.449 , pp. 851-861
  • 37
    • 84904006087 scopus 로고    scopus 로고
    • Rare-variant association analysis: Study designs and statistical tests
    • Lee S, Abecasis GR, Boehnke M, Lin X. 2014. Rare-variant association analysis: study designs and statistical tests. Am J Hum Genet 95: 5-23.
    • (2014) Am J Hum Genet , vol.95 , pp. 5-23
    • Lee, S.1    Abecasis, G.R.2    Boehnke, M.3    Lin, X.4
  • 43
    • 77951439152 scopus 로고    scopus 로고
    • Traitassociated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
    • Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ. 2010. Traitassociated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet 6: e1000888.
    • (2010) PLoS Genet , vol.6 , pp. e1000888
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 45
    • 84924365586 scopus 로고    scopus 로고
    • The genetic and mechanistic basis for variation in gene regulation
    • Pai AA, Pritchard JK, Gilad Y. 2015. The genetic and mechanistic basis for variation in gene regulation. PLoS Genet 11: e1004857.
    • (2015) PLoS Genet , vol.11 , pp. e1004857
    • Pai, A.A.1    Pritchard, J.K.2    Gilad, Y.3
  • 46
    • 84898723939 scopus 로고    scopus 로고
    • Joint analysis of functional genomic data and genomewide association studies of 18 human traits
    • Pickrell JK. 2014. Joint analysis of functional genomic data and genomewide association studies of 18 human traits. Am J Hum Genet 94: 559-573.
    • (2014) Am J Hum Genet , vol.94 , pp. 559-573
    • Pickrell, J.K.1
  • 48
    • 79952263851 scopus 로고    scopus 로고
    • Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals
    • Price AL, Helgason A, Thorleifsson G, McCarroll SA, Kong A, Stefansson K. 2011. Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. PLoS Genet 7: e1001317.
    • (2011) PLoS Genet , vol.7 , pp. e1001317
    • Price, A.L.1    Helgason, A.2    Thorleifsson, G.3    McCarroll, S.A.4    Kong, A.5    Stefansson, K.6
  • 52


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.