Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

Science

Volumn 344, Issue 6183, 2014, Pages 519-523

  Raj, Towfique ^a,b,c   Rothamel, Katie ^b   Mostafavi, Sara ^d   Ye, Chun ^c   Lee, Mark N ^b,c   Replogle, Joseph M ^a,c   Feng, Ting ^b   Lee, Michelle ^a   Asinovski, Natasha ^b   Frohlich, Irene ^a   Imboywa, Selina ^a   Von Korff, Alina ^a   Okada, Yukinori ^a,b,c,e,f   Patsopoulos, Nikolaos A ^a,b,c   Davis, Scott ^b   McCabe, Cristin ^a,c   Paik, Hyun Il ^b   Srivastava, Gyan P ^a,b,c   Raychaudhuri, Soumya ^a,b,c   Hafler, David A ^c,g   Koller, Daphne ^d   Regev, Aviv ^c,h   Hacohen, Nir ^c,i   Mathis, Diane ^b   Benoist, Christophe ^b   Stranger, Barbara E ^j,k   De Jager, Philip L ^a,b,c   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d Stanford University   (United States)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^f RIKEN Center for Integrative Medical Sciences   (Japan)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^j UNIVERSITY OF CHICAGO   (United States)

^k UNIVERSITY OF CHICAGO   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; DISEASE INCIDENCE; IMMUNE SYSTEM; IMMUNITY;

ALLELE; ALZHEIMER DISEASE; ARTICLE; AUTOIMMUNE DISEASE; BLOOD CELL; CD4+ T LYMPHOCYTE; CELL POPULATION; CELL TYPE; GENE; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; HUMAN; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; LEUKOCYTE; MACROPHAGE; MONOCYTE; PARKINSON DISEASE; POLARIZATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE; ADAPTIVE IMMUNITY; AUTOIMMUNITY; DEGENERATIVE DISEASE; ETHNIC GROUP; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MULTIPLE SCLEROSIS; RHEUMATIC FEVER;

TRANSCRIPTOME;

ADAPTIVE IMMUNITY; ALLELES; ALZHEIMER DISEASE; AUTOIMMUNE DISEASES; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; ETHNIC GROUPS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNITY, INNATE; MONOCYTES; MULTIPLE SCLEROSIS; NEURODEGENERATIVE DISEASES; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RHEUMATIC FEVER; TRANSCRIPTOME;

EID: 84900338300     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1249547     Document Type: Article

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