Shifts in the gut metabolome and Clostridium difficile transcriptome throughout colonization and infection in a mouse model

mSphere

Volumn 3, Issue 2, 2018, Pages

  Fletcher, Joshua R ^a   Erwin, Samantha ^a   Lanzas, Cristina ^a   Theriot, Casey M ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Amino acids; Clostridium difficile; Intestinal colonization; Metabolomics; Peptides; Transcriptomics

Indexed keywords

ANTIINFECTIVE AGENT; BRANCHED CHAIN AMINO ACID; PEPTIDE HYDROLASE; PROLINE; TRANSCRIPTOME;

ANIMAL; C57BL MOUSE; CARBOHYDRATE METABOLISM; CECUM; CLOSTRIDIUM INFECTION; FEMALE; GENE EXPRESSION PROFILING; GENETICS; INTESTINE FLORA; MALE; MASS SPECTROMETRY; METABOLISM; METABOLOME; METABOLOMICS; MICROBIOLOGY; MOUSE; PEPTOCLOSTRIDIUM DIFFICILE; SEQUENCE ANALYSIS;

AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; ANTI-BACTERIAL AGENTS; CARBOHYDRATE METABOLISM; CECUM; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; FEMALE; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION PROFILING; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; MICE; MICE, INBRED C57BL; PEPTIDE HYDROLASES; PROLINE; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 85045201454     PISSN: None     EISSN: 23795042     Source Type: Journal    
DOI: 10.1128/mSphere.00089-18     Document Type: Article

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