Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

Nature

Volumn 517, Issue 7533, 2015, Pages 205-208

  Buffie, Charlie G ^a   Bucci, Vanni ^a,b   Stein, Richard R ^a   McKenney, Peter T ^a   Ling, Lilan ^a   Gobourne, Asia ^a   No, Daniel ^a   Liu, Hui ^a   Kinnebrew, Melissa ^a   Viale, Agnes ^a   Littmann, Eric ^a   Van Den Brink, Marcel R M ^a   Jenq, Robert R ^a   Taur, Ying ^a   Sander, Chris ^a   Cross, Justin R ^a   Toussaint, Nora C ^a   Xavier, Joao B ^a   Pamer, Eric G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS DARTMOUTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; BACTERIAL TOXIN; BILE ACID; CLINDAMYCIN; ENROFLOXACIN; RNA 16S; ANTIINFECTIVE AGENT;

ADOPTIVE TRANSFER; ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIUM CULTURE; BILE ACID SYNTHESIS; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; COMMENSALISM; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE AMPLIFICATION; HUMAN; INFECTION RESISTANCE; INFECTION SENSITIVITY; INTESTINE FLORA; MALE; MATHEMATICAL MODEL; MIDDLE AGED; MOUSE; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PHYLOGENETIC TREE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; ANIMAL; C57BL MOUSE; CLOSTRIDIUM; COLITIS; DISEASE PREDISPOSITION; DRUG EFFECTS; EVOLUTION; FECES; GENETICS; INTESTINE; METABOLISM; METAGENOME; MICROBIOLOGY; MICROFLORA; PHYSIOLOGY; SYMBIOSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BILE ACIDS AND SALTS; BIOLOGICAL EVOLUTION; CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE; COLITIS; DISEASE SUSCEPTIBILITY; FECES; FEMALE; HUMANS; INTESTINES; METAGENOME; MICE; MICE, INBRED C57BL; MICROBIOTA; SYMBIOSIS;

EID: 84925500413     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13828     Document Type: Article

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