-
1
-
-
0022646133
-
Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon
-
Mitchell T.J., Ketley J.M., Haslam S.C., et al. Effect of toxin A and B of Clostridium difficile on rabbit ileum and colon. Gut 27 (1986) 78-85
-
(1986)
Gut
, vol.27
, pp. 78-85
-
-
Mitchell, T.J.1
Ketley, J.M.2
Haslam, S.C.3
-
2
-
-
0021995801
-
Effects of Clostridium difficile toxins given intragastrically to animals
-
Lyerly D.M., Saum K.E., MacDonald D.K., et al. Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun 47 (1985) 349-352
-
(1985)
Infect Immun
, vol.47
, pp. 349-352
-
-
Lyerly, D.M.1
Saum, K.E.2
MacDonald, D.K.3
-
3
-
-
0025297184
-
Enterotoxins from Clostridium difficile; diarrhoeogenic potency and morphological effects in the rat intestine
-
Torres J., Jennische E., Lange S., et al. Enterotoxins from Clostridium difficile; diarrhoeogenic potency and morphological effects in the rat intestine. Gut 31 (1990) 781-785
-
(1990)
Gut
, vol.31
, pp. 781-785
-
-
Torres, J.1
Jennische, E.2
Lange, S.3
-
4
-
-
0022618287
-
Purification and properties of Clostridium difficile cytotoxin B
-
Pothoulakis C., Barone L.M., Ely R., et al. Purification and properties of Clostridium difficile cytotoxin B. J Biol Chem 261 (1986) 1316-1321
-
(1986)
J Biol Chem
, vol.261
, pp. 1316-1321
-
-
Pothoulakis, C.1
Barone, L.M.2
Ely, R.3
-
5
-
-
0031408179
-
IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes
-
Linevsky J.K., Pothoulakis C., Keates S., et al. IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes. Am J Physiol Gastrointest Liver Physiol 273 (1997) 1333-1340
-
(1997)
Am J Physiol Gastrointest Liver Physiol
, vol.273
, pp. 1333-1340
-
-
Linevsky, J.K.1
Pothoulakis, C.2
Keates, S.3
-
6
-
-
0033571379
-
Roles of intracellular calcium and NF-kappa B in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes
-
Jefferson K.K., Smith Jr. M.F., and Bobak D.A. Roles of intracellular calcium and NF-kappa B in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes. J Immunol 163 (1999) 5183-5191
-
(1999)
J Immunol
, vol.163
, pp. 5183-5191
-
-
Jefferson, K.K.1
Smith Jr., M.F.2
Bobak, D.A.3
-
7
-
-
0034002331
-
Pseudomembranous colitis caused by a toxin A- B+ strain of Clostridium difficile
-
Limaye A.P., Turgeon D.K., Cookson B.T., et al. Pseudomembranous colitis caused by a toxin A- B+ strain of Clostridium difficile. J Clin Microbiol 38 (2000) 1696-1697
-
(2000)
J Clin Microbiol
, vol.38
, pp. 1696-1697
-
-
Limaye, A.P.1
Turgeon, D.K.2
Cookson, B.T.3
-
8
-
-
0031903191
-
Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR
-
Kato H., Kato N., Watanabe K., et al. Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J Clin Microbiol 36 (1998) 2178-2182
-
(1998)
J Clin Microbiol
, vol.36
, pp. 2178-2182
-
-
Kato, H.1
Kato, N.2
Watanabe, K.3
-
9
-
-
0035909092
-
Fatal pseudomembranous colitis associated with a variant Clostridium difficile strain not detected by toxin A immunoassay
-
Johnson S., Kent S.A., O'leary K.J., et al. Fatal pseudomembranous colitis associated with a variant Clostridium difficile strain not detected by toxin A immunoassay. Ann Intern Med 135 (2001) 434-438
-
(2001)
Ann Intern Med
, vol.135
, pp. 434-438
-
-
Johnson, S.1
Kent, S.A.2
O'leary, K.J.3
-
10
-
-
15544372997
-
Alternative treatments for Clostridium difficile disease: what really works?
-
McFarland L.V. Alternative treatments for Clostridium difficile disease: what really works?. J Med Microbiol 54 (2005) 101-111
-
(2005)
J Med Microbiol
, vol.54
, pp. 101-111
-
-
McFarland, L.V.1
-
11
-
-
0019029022
-
Mucosal damage mediated by clostridial toxin in experimental clindamycin-associated colitis
-
Abrams G.D., Allo M., Rifkin G.D., et al. Mucosal damage mediated by clostridial toxin in experimental clindamycin-associated colitis. Gut 21 (1980) 493-499
-
(1980)
Gut
, vol.21
, pp. 493-499
-
-
Abrams, G.D.1
Allo, M.2
Rifkin, G.D.3
-
12
-
-
0020659377
-
Pseudomembranous colitis in Clostridium difficile-monoassociated rats
-
Czuprynski C.J., Johnson W.J., Balish E., et al. Pseudomembranous colitis in Clostridium difficile-monoassociated rats. Infect Immun 39 (1983) 1368-1376
-
(1983)
Infect Immun
, vol.39
, pp. 1368-1376
-
-
Czuprynski, C.J.1
Johnson, W.J.2
Balish, E.3
-
13
-
-
0018439376
-
Antibiotic-associated colitis: effects of antibiotics on Clostridium difficile and the disease in hamsters
-
Fekety R., Silva J., Toshniwal R., et al. Antibiotic-associated colitis: effects of antibiotics on Clostridium difficile and the disease in hamsters. Rev Infect Dis 1 (1979) 386-397
-
(1979)
Rev Infect Dis
, vol.1
, pp. 386-397
-
-
Fekety, R.1
Silva, J.2
Toshniwal, R.3
-
14
-
-
0018316798
-
Clindamycin-associated enterocolitis in guinea pigs: evidence for a bacterial toxin
-
Knoop F.C. Clindamycin-associated enterocolitis in guinea pigs: evidence for a bacterial toxin. Infect Immun 23 (1979) 31-33
-
(1979)
Infect Immun
, vol.23
, pp. 31-33
-
-
Knoop, F.C.1
-
15
-
-
0028818809
-
Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters
-
Torres J.F., Lyerly D.M., Hill J.E., et al. Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters. Infect Immun 63 (1995) 4619-4627
-
(1995)
Infect Immun
, vol.63
, pp. 4619-4627
-
-
Torres, J.F.1
Lyerly, D.M.2
Hill, J.E.3
-
16
-
-
0031948840
-
Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection
-
Kink J.A., and Williams J.A. Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection. Infect Immun 66 (1998) 2018-2025
-
(1998)
Infect Immun
, vol.66
, pp. 2018-2025
-
-
Kink, J.A.1
Williams, J.A.2
-
17
-
-
0032962874
-
Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters
-
Giannasca P.J., Zhang Z.X., Lei W.D., et al. Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters. Infect Immun 67 (1999) 527-538
-
(1999)
Infect Immun
, vol.67
, pp. 527-538
-
-
Giannasca, P.J.1
Zhang, Z.X.2
Lei, W.D.3
-
18
-
-
0022648984
-
Gnotobiotic models for study of the microbial ecology of Clostridium difficile and Escherichia coli
-
Wilson K.H., Sheagren J.N., Freter R., et al. Gnotobiotic models for study of the microbial ecology of Clostridium difficile and Escherichia coli. J Infect Dis 153 (1986) 547-551
-
(1986)
J Infect Dis
, vol.153
, pp. 547-551
-
-
Wilson, K.H.1
Sheagren, J.N.2
Freter, R.3
-
19
-
-
0021978275
-
Experimental models of Clostridium difficile enterocolitis in gnotobiotic mice
-
Sugiyama T., Mukai M., Yamashita R., et al. Experimental models of Clostridium difficile enterocolitis in gnotobiotic mice. Prog Clin Biol Res 181 (1985) 203-206
-
(1985)
Prog Clin Biol Res
, vol.181
, pp. 203-206
-
-
Sugiyama, T.1
Mukai, M.2
Yamashita, R.3
-
21
-
-
4644220669
-
Rifalazil treats and prevents relapse of Clostridium difficile-associated diarrhea in hamsters
-
Anton P.M., O'Brien M., Kokkotou E., et al. Rifalazil treats and prevents relapse of Clostridium difficile-associated diarrhea in hamsters. Antimicrob Agents Chemother 48 (2004) 3975-3979
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3975-3979
-
-
Anton, P.M.1
O'Brien, M.2
Kokkotou, E.3
-
22
-
-
40549090894
-
Comparative efficacies of rifaximin and vancomycin for treatment of Clostridium difficile-associated diarrhea and prevention of disease recurrence in hamsters
-
Kokkotou E., Moss A.C., Michos A., et al. Comparative efficacies of rifaximin and vancomycin for treatment of Clostridium difficile-associated diarrhea and prevention of disease recurrence in hamsters. Antimicrob Agents Chemother 52 (2008) 1121-1126
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1121-1126
-
-
Kokkotou, E.1
Moss, A.C.2
Michos, A.3
-
23
-
-
0035877043
-
Infection of hamsters with epidemiologically important strains of Clostridium difficile
-
Sambol S.P., Tang J.K., Merrigan M.M., et al. Infection of hamsters with epidemiologically important strains of Clostridium difficile. J Infect Dis 183 (2001) 1760-1766
-
(2001)
J Infect Dis
, vol.183
, pp. 1760-1766
-
-
Sambol, S.P.1
Tang, J.K.2
Merrigan, M.M.3
-
24
-
-
0030064139
-
Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins
-
Kelly C.P., Pothoulakis C., Vavva F., et al. Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins. Antimicrob Agents Chemother 40 (1996) 373-379
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 373-379
-
-
Kelly, C.P.1
Pothoulakis, C.2
Vavva, F.3
-
25
-
-
0028316383
-
Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit
-
Kelly C.P., Becker S., Linevsky J.K., et al. Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit. J Clin Invest 93 (1994) 1257-1265
-
(1994)
J Clin Invest
, vol.93
, pp. 1257-1265
-
-
Kelly, C.P.1
Becker, S.2
Linevsky, J.K.3
-
26
-
-
0034670017
-
Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major
-
Julia V., McSorley S.S., Malherbe L., et al. Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major. J Immunol 165 (2000) 5637-5645
-
(2000)
J Immunol
, vol.165
, pp. 5637-5645
-
-
Julia, V.1
McSorley, S.S.2
Malherbe, L.3
-
29
-
-
0018139402
-
Clindamycin-induced enterocolitis in hamsters
-
Lusk R.H., Fekety R., Silva J., et al. Clindamycin-induced enterocolitis in hamsters. J Infect Dis 137 (1978) 464-475
-
(1978)
J Infect Dis
, vol.137
, pp. 464-475
-
-
Lusk, R.H.1
Fekety, R.2
Silva, J.3
-
30
-
-
0019767313
-
Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis
-
Wilson K.H., Silva J., and Fekety F.R. Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis. Infect Immun 34 (1981) 626-628
-
(1981)
Infect Immun
, vol.34
, pp. 626-628
-
-
Wilson, K.H.1
Silva, J.2
Fekety, F.R.3
-
31
-
-
33749023005
-
Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication
-
Hamm E.E., Voth D.E., and Ballard J.D. Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication. Proc Natl Acad Sci U S A 103 (2006) 14176-14181
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14176-14181
-
-
Hamm, E.E.1
Voth, D.E.2
Ballard, J.D.3
-
32
-
-
33750493617
-
Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile -induced mortality in hamsters
-
Babcock G.J., Broering T.J., Hernandez H.J., et al. Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile -induced mortality in hamsters. Infect Immun 74 (2006) 6339-6347
-
(2006)
Infect Immun
, vol.74
, pp. 6339-6347
-
-
Babcock, G.J.1
Broering, T.J.2
Hernandez, H.J.3
-
33
-
-
0034628426
-
Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
-
Kyne L., Warny M., Qamar A., et al. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 342 (2000) 390-397
-
(2000)
N Engl J Med
, vol.342
, pp. 390-397
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
-
34
-
-
0035915688
-
Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
-
Kyne L., Warny M., Qamar A., et al. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 357 (2001) 189-193
-
(2001)
Lancet
, vol.357
, pp. 189-193
-
-
Kyne, L.1
Warny, M.2
Qamar, A.3
-
35
-
-
0033163474
-
Pseudomembranous colitis: spectrum of imaging findings with clinical and pathologic correlation
-
Kawamoto S., Horton K.M., and Fishman E.K. Pseudomembranous colitis: spectrum of imaging findings with clinical and pathologic correlation. Radiographics 19 (1999) 887-897
-
(1999)
Radiographics
, vol.19
, pp. 887-897
-
-
Kawamoto, S.1
Horton, K.M.2
Fishman, E.K.3
-
36
-
-
33845304266
-
Update on Clostridium difficile associated disease
-
Cloud J., and Kelly C.P. Update on Clostridium difficile associated disease. Curr Opin Gastroenterol 23 (2007) 4-9
-
(2007)
Curr Opin Gastroenterol
, vol.23
, pp. 4-9
-
-
Cloud, J.1
Kelly, C.P.2
-
37
-
-
0036467063
-
Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile
-
Kyne L., Hamel M.B., Polavaram R., et al. Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile. Clin Infect Dis 34 (2002) 346-353
-
(2002)
Clin Infect Dis
, vol.34
, pp. 346-353
-
-
Kyne, L.1
Hamel, M.B.2
Polavaram, R.3
-
38
-
-
32544446901
-
Severe Clostridium difficile-associated disease in populations previously at low risk--four states, 2005
-
CDC. CfDCaP
-
CDC. CfDCaP. Severe Clostridium difficile-associated disease in populations previously at low risk--four states, 2005. MMWR Morb Mortal Wkly Rep 54 (2005) 1201-1205
-
(2005)
MMWR Morb Mortal Wkly Rep
, vol.54
, pp. 1201-1205
-
-
-
39
-
-
33845609225
-
Emerging therapies in the treatment of Clostridium difficile-associated disease
-
Jodlowski T.Z., Oehler R., Kam L.W., et al. Emerging therapies in the treatment of Clostridium difficile-associated disease. Ann Pharmacother 40 (2006) 2164-2169
-
(2006)
Ann Pharmacother
, vol.40
, pp. 2164-2169
-
-
Jodlowski, T.Z.1
Oehler, R.2
Kam, L.W.3
-
40
-
-
0031967123
-
Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice
-
Wershil B.K., Castagliuolo I., and Pothoulakis C. Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice. Gastroenterology 114 (1998) 956-964
-
(1998)
Gastroenterology
, vol.114
, pp. 956-964
-
-
Wershil, B.K.1
Castagliuolo, I.2
Pothoulakis, C.3
-
41
-
-
23044492161
-
Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice
-
Pultz N.J., and Donskey C.J. Effect of antibiotic treatment on growth of and toxin production by Clostridium difficile in the cecal contents of mice. Antimicrob Agents Chemother 49 (2005) 3529-3532
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3529-3532
-
-
Pultz, N.J.1
Donskey, C.J.2
-
42
-
-
0024367817
-
Interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by Clostridium difficile in gnotobiotic mice
-
Corthier G., Muller M.C., Elmer G.W., et al. Interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by Clostridium difficile in gnotobiotic mice. Infect Immun 57 (1989) 3922-3927
-
(1989)
Infect Immun
, vol.57
, pp. 3922-3927
-
-
Corthier, G.1
Muller, M.C.2
Elmer, G.W.3
|