Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

Cell Reports

Volumn 22, Issue 11, 2018, Pages 2924-2936

  Kambara, Hiroto ^a,b   Liu, Fei ^c   Zhang, Xiaoyu ^a,b,c   Liu, Peng ^c   Bajrami, Besnik ^d   Teng, Yan ^a,b   Zhao, Li ^a,b   Zhou, Shiyi ^a,b   Yu, Hongbo ^e   Zhou, Weidong ^f   Silberstein, Leslie E ^a,b   Cheng, Tao ^c   Han, Mingzhe ^c   Xu, Yuanfu ^c   Luo, Hongbo R ^a,b  

^a DANA FARBER HARVARD CANCER CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f GEORGE MASON UNIVERSITY   (United States)

Author keywords

GSDMD; host defense; innate immunity; neutrophil death; neutrophil elastase

Indexed keywords

CASPASE; CYTOKINE; GASDERMIN D; LEUKOCYTE ELASTASE; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; APOPTOSIS REGULATORY PROTEIN; GSDMD PROTEIN, MOUSE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ESCHERICHIA COLI; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PYROPTOSIS; ANIMAL; DRUG EFFECT; HUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS REGULATORY PROTEINS; CELL DEATH; HUMANS; MICE; NEUTROPHILS;

EID: 85043591156     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2018.02.067     Document Type: Article

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