Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 19, 2013, Pages 7726-7731

  Xu, Yuanfu ^a   Li, Hongmei ^b   Bajrami, Besnik ^b   Kwak, Hyunjeong ^b   Cao, Shannan ^a   Liu, Peng ^a   Zhou, Jiaxi ^a   Zhou, Yuan ^a   Zhu, Haiyan ^a   Ye, Keqiang ^c   Luo, Hongbo R ^b  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CIGARETTE SMOKE; CYTOKINE; DIPHOSPHOINOSITOL PENTAKISPHOSPHATE; INOSITOL HEXAKISPHOSPHATE KINASE; INOSITOL PHOSPHATE; NICOTINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG INJURY; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DEATH; CELL MEMBRANE; CELL SEPARATION; FLOW CYTOMETRY; INOSITOL PHOSPHATES; LUNG; MICE; MICE, KNOCKOUT; NEUTROPHILS; NICOTINE; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; SMOKING; TIME FACTORS;

EID: 84877350576     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302906110     Document Type: Article

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