Biosynthesis of a ganoderic acid in Saccharomyces cerevisiae by expressing a cytochrome P450 gene from Ganoderma lucidum

Biotechnology and Bioengineering

Volumn 115, Issue 7, 2018, Pages 1842-1854

  Wang, Wen Fang ^a   Xiao, Han ^a   Zhong, Jian Jiang ^a  

^a Shanghai Jiao Tong University   (China)

Author keywords

cytochrome P450 monooxygenase (CYP450); medicinal mushroom; Saccharomyces cerevisiae; secondary metabolite biosynthesis; synthetic biology; triterpenoid

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; DRUG PRODUCTS; GENES; METABOLITES;

MEDICINAL MUSHROOM; MONOOXYGENASES; SECONDARY METABOLITES; SYNTHETIC BIOLOGY; TRITERPENOIDS;

YEAST;

CYTOCHROME P450; GANODERIC ACID; LANOSTEROL; TRITERPENOID; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN; TRITERPENE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG SYNTHESIS; FERMENTATION; GANODERMA LUCIDUM; GENE EXPRESSION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMONUCLEAR CORRELATION SPECTROSCOPY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; SPECTROSCOPY; SUPPRESSION SUBTRACTIVE HYBRIDIZATION; UPREGULATION; BIOTRANSFORMATION; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; LANOSTEROL; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; METABOLIC NETWORKS AND PATHWAYS; RECOMBINANT PROTEINS; REISHI; SACCHAROMYCES CEREVISIAE; TRITERPENES;

EID: 85043375753     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.26583     Document Type: Article

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