Enhancement of ganoderic acid accumulation by overexpression of an n-terminally truncated 3-hydroxy-3-methylglutaryl coenzyme a reductase gene in the basidiomycete Ganoderma lucidum

Applied and Environmental Microbiology

Volumn 78, Issue 22, 2012, Pages 7968-7976

  Xu, Jun Wei ^a   Xu, Yi Ning ^a   Zhong, Jian Jiang ^a  

^a Shanghai Jiao Tong University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE; AGROBACTERIUM TUMEFACIENS-MEDIATED TRANSFORMATION; ANTI-TUMORS; CATALYTIC DOMAINS; FARNESYL PYROPHOSPHATES; GANODERIC ACID; GANODERMA LUCIDUM; GENETIC MODIFICATIONS; GENETIC TRANSFORMATION SYSTEMS; IRON-SULFUR PROTEINS; LANOSTEROL; MEDICINAL MUSHROOM; OVER-EXPRESSION; SELECTION MARKER; SUCCINATE DEHYDROGENASE; SYNTHASES; TRANSGENICS; UP-REGULATION;

DRUG PRODUCTS; GENE ENCODING; GENETIC ENGINEERING; NUCLEIC ACIDS; SULFUR;

FUNGI;

FUNGAL DNA; GANODERIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH); TRITERPENE;

ACCUMULATION; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ENGINEERING; MEDICINAL PLANT; MUSHROOM; PROTEIN; TRANSFORMATION;

ARTICLE; CHEMISTRY; DNA SEQUENCE; ENZYMOLOGY; GANODERMA LUCIDUM; GENETIC TRANSFORMATION; GENETICS; METABOLIC ENGINEERING; METABOLISM; METHODOLOGY; MICROBIAL GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RHIZOBIUM RADIOBACTER;

AGROBACTERIUM TUMEFACIENS; DNA, FUNGAL; GENETICS, MICROBIAL; HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT; METABOLIC ENGINEERING; MOLECULAR SEQUENCE DATA; REISHI; SEQUENCE ANALYSIS, DNA; TRANSFORMATION, GENETIC; TRITERPENES;

CHINA;

AGROBACTERIUM TUMEFACIENS; BASIDIOMYCOTA; GANODERMA LUCIDUM;

EID: 84868610107     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01263-12     Document Type: Article

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