Biosynthesis of plant-derived ginsenoside Rh2 in yeast via repurposing a key promiscuous microbial enzyme

Metabolic Engineering

Volumn 42, Issue , 2017, Pages 25-32

  Zhuang, Yu ^a   Yang, Guang Yu ^a   Chen, Xiaohui ^a   Liu, Qian ^a   Zhang, Xueli ^b   Deng, Zixin ^a   Feng, Yan ^a  

^a Shanghai Jiao Tong University   (China)

^b Chinese Academy of Sciences   (China)

Author keywords

Enzyme promiscuity; Ginsenoside; Glycosyltransferase; Metabolic engineering; Protein engineering; Synthetic biology

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; ENZYMES; METABOLISM; PLANTS (BOTANY); YEAST;

CATALYTIC EFFICIENCIES; FED-BATCH FERMENTATION; FERMENTATIVE PRODUCTION; GINSENOSIDES; GLYCOSYL TRANSFERASE; HIGH-LEVEL PRODUCTION; PROTEIN ENGINEERING; SYNTHETIC BIOLOGY;

METABOLIC ENGINEERING;

FUNGAL ENZYME; GINSENOSIDE RH 2; GLYCOSYLTRANSFERASE; PROTOPANAXADIOL; GINSENOSIDE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; BIOSYNTHESIS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ENGINEERING; FED BATCH FERMENTATION; FED BATCH REACTOR; FUNGAL CELL; FUNGAL STRAIN; GINSENG; GLYCOSYLATION; IN VITRO STUDY; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; GENETICS; METABOLISM;

GINSENOSIDES; GLYCOSYLTRANSFERASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 85019895069     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.04.009     Document Type: Article

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