Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms

Nature Structural and Molecular Biology

Volumn 25, Issue 3, 2018, Pages 252-260

  Deng, Zengqin ^a   Paknejad, Navid ^b   Maksaev, Grigory ^a   Sala Rabanal, Monica ^a   Nichols, Colin G ^a   Hite, Richard K ^b   Yuan, Peng ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION CHANNEL; VANILLOID RECEPTOR 4; ION; VANILLOID RECEPTOR; XENOPUS PROTEIN;

ARTICLE; BINDING SITE; CHANNEL GATING; COMPARATIVE STUDY; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; XENOPUS TROPICALIS; ANIMAL; CHANNELOPATHY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR MODEL; MUTATION; PERMEABILITY; PROTEIN DOMAIN;

ANIMALS; CHANNELOPATHIES; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; HUMANS; ION CHANNEL GATING; IONS; MODELS, MOLECULAR; MUTATION; PERMEABILITY; PROTEIN DOMAINS; TRPV CATION CHANNELS; XENOPUS PROTEINS;

EID: 85042587034     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/s41594-018-0037-5     Document Type: Article

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