TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2

Nature Communications

Volumn 5, Issue , 2014, Pages

  Takahashi, Nobuaki ^a   Hamada Nakahara, Sayaka ^b   Itoh, Yuzuru ^b   Takemura, Kazuhiro ^b   Shimada, Atsushi ^c   Ueda, Yoshifumi ^a   Kitamata, Manabu ^b,d   Matsuoka, Rei ^c   Hanawa Suetsugu, Kyoko ^b,d   Senju, Yosuke ^b   Mori, Masayuki X ^a   Kiyonaka, Shigeki ^a   Kohda, Daisuke ^c   Kitao, Akio ^b   Mori, Yasuo ^a   Suetsugu, Shiro ^d  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANKYRIN; INOSITOL 1,4,5 TRISPHOSPHATE; MEMBRANE LIPID; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPID BINDING PROTEIN; VANILLOID RECEPTOR 4; PROTEIN BINDING; TRPV4 PROTEIN, HUMAN; VANILLOID RECEPTOR;

AMINO ACID; CHANNELIZATION; HYDROLYSIS; LIPID; MUTATION; PHENOTYPE; SIMULATION;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; GAIN OF FUNCTION MUTATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYDROLYSIS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PHENOTYPE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TITRIMETRY; ANIMAL; CHEMISTRY; CHICKEN; GENETICS; METABOLISM; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANKYRIN REPEAT; CHICKENS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MOLECULAR DYNAMICS SIMULATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN BINDING; TRPV CATION CHANNELS;

EID: 84923349290     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5994     Document Type: Article

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