Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip article

Cell Death and Disease

Volumn 9, Issue 2, 2018, Pages

  Jalili Firoozinezhad, Sasan ^a,b   Prantil Baun, Rachelle ^a   Jiang, Amanda ^c   Potla, Ratnakar ^c   Mammoto, Tadanori ^c   Weaver, James C ^a   Ferrante, Thomas C ^a   Kim, Hyun Jung ^d   Cabral, Joaquim M S ^b   Levy, Oren ^a   Ingber, Donald E ^a,c,e  

^a HARVARD UNIVERSITY   (United States)

^b INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d The University of Texas at Austin   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLOXALOYLGLYCINE; DOUBLE STRANDED DNA; GLYCINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MUCIN 2; OXYGENASE INHIBITOR; RADIOPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; DICARBOXYLIC AMINO ACID; OXALYLGLYCINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL DISRUPTION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA FRAGMENTATION; DRUG RESPONSE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; INTESTINE VILLUS; IONIZING RADIATION; MICROFLUIDICS; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; TIGHT JUNCTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIAL CELL; WHOLE BODY RADIATION; ADVERSE EVENT; ANIMAL; BIOLOGICAL MODEL; CACO-2 CELL LINE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GAMMA RADIATION; INTESTINE MUCOSA; LAB ON A CHIP; LIPID PEROXIDATION; METABOLISM; PATHOLOGY; PERMEABILITY; RADIATION RESPONSE;

AMINO ACIDS, DICARBOXYLIC; ANIMALS; APOPTOSIS; CACO-2 CELLS; CELLS, CULTURED; DNA FRAGMENTATION; GAMMA RAYS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; LAB-ON-A-CHIP DEVICES; LIPID PEROXIDATION; MODELS, BIOLOGICAL; PERMEABILITY; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; TIGHT JUNCTIONS;

EID: 85042066061     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/s41419-018-0304-8     Document Type: Article

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