Cerium oxide nanoparticles protect gastrointestinal epithelium from radiation-induced damage by reduction of reactive oxygen species and upregulation of superoxide dismutase 2

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 6, Issue 5, 2010, Pages 698-705

  Colon, Jimmie ^a   Hsieh, Nelson ^a   Ferguson, Amber ^a   Kupelian, Patrick ^a   Seal, Sudipta ^b,c   Jenkins, D Wayne ^a   Baker, Cheryl H ^a,d  

^a M D ANDERSON CANCER CENTER ORLANDO   (United States)

^b University of Central Florida   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

^d UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cerium oxide nanoparticles; Gastrointestinal epithelium; Radioprotection; SOD2

Indexed keywords

ATHYMIC; CASPASE-3; CERIUM OXIDE NANOPARTICLE; CERIUM OXIDES; DOSE-DEPENDENT MANNER; GASTROINTESTINAL EPITHELIUM; HUMAN COLON; IMMUNOHISTOCHEMICAL ANALYSIS; INTRAPERITONEAL INJECTIONS; NUDE MICE; PRE-TREATMENT; RADIATION EXPOSURE; RADIATION-INDUCED; RADIATION-INDUCED DAMAGES; RADICAL SCAVENGERS; RADIOPROTECTION; REACTIVE OXYGEN SPECIES; SHARP CONTRAST; SINGLE-DOSE; SOD2; SUPEROXIDE DISMUTASE 2; UP-REGULATION;

CELL DEATH; CERIUM; CERIUM COMPOUNDS; NANOPARTICLES; OXIDES; OXYGEN; RADIATION; RARE EARTHS;

RADIATION PROTECTION;

CASPASE 3; CERIUM OXIDE; CERIUM OXIDE NANOPARTICLE; FREE RADICAL; MANGANESE SUPEROXIDE DISMUTASE; RADIOPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EPITHELIUM CELL; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; RANDOMIZED CONTROLLED TRIAL; UPREGULATION;

ANIMALS; CELL LINE; CELL SURVIVAL; CERIUM; ENZYME ACTIVATION; GASTROINTESTINAL TRACT; HUMANS; MICE; MICE, NUDE; MUCOUS MEMBRANE; NANOPARTICLES; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 77957151977     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2010.01.010     Document Type: Article

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