Activation of Nrf2 by Ginsenoside Rh3 protects retinal pigment epithelium cells and retinal ganglion cells from UV

Free Radical Biology and Medicine

Volumn 117, Issue , 2018, Pages 238-246

  Tang, Chun zhou ^a,b   Li, Ke Ran ^a   Yu, Qing ^a   Jiang, Qin ^a   Yao, Jin ^a   Cao, Cong ^a,c,d  

^a First Affiliated Hospital of Nanjing Medical University   (China)

^b JIANGYIN PEOPLE S HOSPITAL   (China)

^c SOOCHOW UNIVERSITY   (China)

^d Municipal Hospital of Suzhou   (China)

Author keywords

Ginsenoside Rh3; MicroRNA 141; Nrf2, UV radiation; Oxidative stress; Retinal cells

Indexed keywords

ANTAGOMIR; ANTAGOMIR 141; GINSENOSIDE; GINSENOSIDE RH3; MICRORNA 141; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EPITHELIUM CELL; GCLC GENE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN; GENE TARGETING; HO1 GENE; HUMAN; HUMAN CELL; IN VIVO STUDY; KEAP1 GENE; MALE; MOUSE; NONHUMAN; NOQ1 GENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN STABILITY; RETINA DISEASE; RETINA GANGLION CELL; RETINAL PIGMENT EPITHELIUM; RNA GENE; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION; ANIMAL; DRUG EFFECT; ENZYME ACTIVATION; EXPERIMENTAL RADIATION INJURY; METABOLISM;

ANIMALS; ENZYME ACTIVATION; GINSENOSIDES; HUMANS; MICE; NF-E2-RELATED FACTOR 2; RADIATION INJURIES, EXPERIMENTAL; RETINAL GANGLION CELLS; RETINAL PIGMENT EPITHELIUM; ULTRAVIOLET RAYS;

EID: 85042036105     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2018.02.001     Document Type: Article

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