Requirement of Gαi1/3–Gab1 Signaling Complex for Keratinocyte Growth Factor–Induced PI3K–AKT–mTORC1 Activation

Journal of Investigative Dermatology

Volumn 135, Issue 1, 2015, Pages 181-191

  Zhang, Yi ming ^a   Zhang, Zhi qing ^b   Liu, Yuan yuan ^b   Zhou, Xin ^a   Shi, Xiao hua ^a   Jiang, Qin ^c   Fan, Dong li ^a   Cao, Cong ^b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; COMPLEMENTARY DNA; CYCLIN D1; FIBROBLAST GROWTH FACTOR 10; FIBRONECTIN; GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BINDING 2 ASSOCIATED BINDING PROTEIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; KERATINOCYTE GROWTH FACTOR; KERATINOCYTE GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; PROTEIN P85; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; PLATELET DERIVED GROWTH FACTOR; FGF7 PROTEIN, HUMAN; GAB1 PROTEIN, HUMAN; GNAI1 PROTEIN, HUMAN; GNAI2 PROTEIN, HUMAN; GNAI3 PROTEIN, HUMAN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; DOSE RESPONSE; EMBRYO; ENZYME ACTIVATION; EXPRESSION VECTOR; GENETIC TRANSFECTION; HEK293 CELL LINE; KERATINOCYTE; MOUSE; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STABLE EXPRESSION; WESTERN BLOTTING; BIOACCUMULATION; CELL STIMULATION; CLINICAL ASSESSMENT; GENE SILENCING; HUMAN; HUMAN TISSUE; KELOID; PROTEIN EXPRESSION; SKIN CULTURE; SKIN FIBROBLAST; SKIN INJURY; WOUND HEALING; CELL MOTION; CYTOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SKIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL MOVEMENT; FIBROBLAST GROWTH FACTOR 7; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEK293 CELLS; HUMANS; KELOID; KERATINOCYTES; MULTIPROTEIN COMPLEXES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SKIN; TOR SERINE-THREONINE KINASES;

EID: 84925229474     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.326     Document Type: Article

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