SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling

Oncotarget

Volumn 7, Issue 37, 2016, Pages 60123-60132

  Gong, Yi qing ^a,b   Huang, Wei ^a   Li, Ke ran ^a   Liu, Yuan yuan ^c   Cao, Guo fan ^a   Cao, Cong ^c   Jiang, Qin ^a  

^a First Affiliated Hospital of Nanjing Medical University   (China)

^b AFFILIATED PEOPLE S HOSPITAL OF JIANGSU UNIVERSITY   (China)

^c SOOCHOW UNIVERSITY   (China)

Author keywords

Nrf2 signaling; Retinal pigment epithelium; SC79Akt; UV

Indexed keywords

8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ENZYME ACTIVATOR; PROTEIN KINASE B; SC 79; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 2-AMINO-6-CHLORO-ALPHA-CYANO-3-(ETHOXYCARBONYL)-4H-1-BENZOPYRAN-4-ACETIC ACID ETHYL ESTER; ACETIC ACID DERIVATIVE; BENZOPYRAN DERIVATIVE; FUSED HETEROCYCLIC RINGS; NFE2L2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; RETINA INJURY; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL CULTURE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; MUTATION; RADIATION RESPONSE; RNA INTERFERENCE;

ACETATES; ANIMALS; APOPTOSIS; BENZOPYRANS; CELL LINE; CELLS, CULTURED; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MALE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; MUTATION; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RETINAL PIGMENT EPITHELIUM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 84988378790     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11164     Document Type: Article

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