Ultra-violet B (UVB)-induced skin cell death occurs through a cyclophilin D intrinsic signaling pathway

Biochemical and Biophysical Research Communications

Volumn 425, Issue 4, 2012, Pages 825-829

  Ji, Chao ^a   Yang, Bo ^b   Yang, Zhi ^c   Tu, Ying ^c   Yang, Yan Li ^a   He, Li ^a   Bi, Zhi Gang ^d  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c KUNMING MEDICAL UNIVERSITY   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cyclophilin D; Skin cell damage; UVB radiation

Indexed keywords

CYCLOPHILIN D; CYCLOSPORIN A; HYDROGEN PEROXIDE;

ARTICLE; CELL CULTURE; CELL DEATH; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; LENTIVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ULTRAVIOLET B RADIATION; UPREGULATION;

APOPTOSIS; CELL LINE; CYCLOPHILINS; HUMANS; HYDROGEN PEROXIDE; KERATINOCYTES; SIGNAL TRANSDUCTION; SKIN; SKIN AGING; ULTRAVIOLET RAYS;

EID: 84865970032     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.160     Document Type: Article

References (24)

1. Kappes U.P., Luo D., Potter M., Schulmeister K., Runger T.M. Short- and long-wave UV light (UVB and UVA) induce similar mutations in human skin cells. J. Invest. Dermatol. 2006, 126:667-675.
2. Brash D.E., Ziegler A., Jonason A.S., Simon J.A., Kunala S., Leffell D.J. Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion. J. Investig. Dermatol. Symp. Proc. 1996, 1:136-142.
3. Gilchrest B.A., Eller M.S., Geller A.C., Yaar M. The pathogenesis of melanoma induced by ultraviolet radiation. N. Engl. J. Med. 1999, 340:1341-1348.
4. De Fabo E.C. Arctic stratospheric ozone depletion and increased UVB radiation: potential impacts to human health. Int. J. Circumpolar. Health. 2005, 64:509-522.
5. Yang B., Ji C., Chen X., Cui L., Bi Z., Wan Y., Xu J. Protective effect of astragaloside IV against matrix metalloproteinase-1 expression in ultraviolet-irradiated human dermal fibroblasts. Arch. Pharm. Res. 2011, 34:1553-1560.
6. Ji C., Yang Y.L., Yang Z., Tu Y., Cheng L., Chen B., Xia J.P., Sun W.L., Su Z.L., He L., Bi Z.G. Perifosine sensitizes UVB-induced apoptosis in skin cells: new implication of skin cancer prevention?. Cell. Signal. 2012, 24:1781-1789.
7. Shan S.J., Xiao T., Chen J., Geng S.L., Li C.P., Xu X., Hong Y., Ji C., Guo Y., Wei H., Liu W., Li D., Chen H.D. Kanglaite attenuates UVB-induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int. J. Mol. Med. 2012, 29:625-629.
8. Ji C., Yang Y., Yang B., Xia J., Sun W., Su Z., Yu L., Shan S., He S., Cheng L., Wan Y., Bi Z. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int. J. Mol. Med. 2010, 26:257-263.
9. Halestrap A. Biochemistry: a pore way to die. Nature 2005, 434:578-579.
10. Crompton M. Mitochondria and aging: a role for the permeability transition?. Aging Cell. 2004, 3:3-6.
11. Halestrap A.P., McStay G.P., Clarke S.J. The permeability transition pore complex: another view. Biochimie 2002, 84:153-166.
12. Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A., Brunskill E.W., Sayen M.R., Gottlieb R.A., Dorn G.W., Robbins J., Molkentin J.D. Loss of Cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005, 434:658-662.
13. Crompton M., Virji S., Ward J.M. Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore. Eur. J. Biochem. 1998, 258:729-735.
14. Halestrap A.P., Woodfield K.Y., Connern C.P. Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J. Biol. Chem. 1997, 272:3346-3354.
15. Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., Inohara H., Kubo T., Tsujimoto Y. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005, 434:652-658.
16. Schinzel A.C., Takeuchi O., Huang Z., Fisher J.K., Zhou Z., Rubens J., Hetz C., Danial N.N., Moskowitz M.A., Korsmeyer S.J. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc. Natl. Acad. Sci. USA 2005, 102:12005-12010.
17. Basso E., Fante L., Fowlkes J., Petronilli V., Forte M.A., Bernardi P. Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. J. Biol. Chem. 2005, 280:18558-18561.
18. Yang B., Ji C., Kang J., Chen W., Bi Z., Wan Y. Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Int. J. Mol. Med. 2009, 23:555-560.
19. Ji C., Yang B., Yang Y.L., He S.H., Miao D.S., He L., Bi Z.G. Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition. Oncogene 2010, 29:6557-6568.
20. Zhu Q.Y., Wang Z., Ji C., Cheng L., Yang Y.L., Ren J., Jin Y.H., Wang Q.J., Gu X.J., Bi Z.G., Hu G., Yang Y. C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and alpha-tubulin hyperacetylation both in vitro and in vivo. Cell. Death Dis. 2011, 2:e117.
21. Ji C., Yang Y.L., He L., Gu B., Xia J.P., Sun W.L., Su Z.L., Chen B., Bi Z.G. Increasing ceramides sensitizes genistein-induced melanoma cell apoptosis and growth inhibition. Biochem. Biophys. Res. Commun. 2012, 421:462-467.
22. Baines C.P. The molecular composition of the mitochondrial permeability transition pore. J. Mol. Cell. Cardiol. 2009, 46:850-857.
23. Du H., Guo L., Fang F., Chen D., Sosunov A.A., McKhann G.M., Yan Y., Wang C., Zhang H., Molkentin J.D., Gunn-Moore F.J., Vonsattel J.P., Arancio O., Chen J.X., Yan S.D. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat. Med. 2008, 14:1097-1105.
24. Du H., Guo L., Zhang W., Rydzewska M., Yan S. Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model. Neurobiol. Aging 2011, 32:398-406.