Ginsenoside Rg5:Rk1 attenuates TNF-α/IFN-γ-induced production of thymus- and activation-regulated chemokine (TARC/CCL17) and LPS-induced NO production via downregulation of NF-κB/p38 MAPK/STAT1 signaling in human keratinocytes and macrophages

In Vitro Cellular and Developmental Biology - Animal

Volumn 52, Issue 3, 2016, Pages 287-295

  Ahn, Sungeun ^a   Siddiqi, Muhammad Hanif ^a   Aceituno, Veronica Castro ^a   Simu, Shakina Yesmin ^a   Zhang, Jinglou ^a   Jimenez Perez, Zuly Elizabeth ^a   Kim, Yu Jin ^a   Yang, Deok Chun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Atopic dermatitis; Inflammation; Keratinocytes macrophages TARC CCL17; NF B; p38 MAPK; STAT1

Indexed keywords

CCL22 PROTEIN, HUMAN; GAMMA INTERFERON; GINSENOSIDE; GINSENOSIDE RG5; I KAPPA B KINASE; LIPOPOLYSACCHARIDE; MACROPHAGE DERIVED CHEMOKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; RELA PROTEIN, HUMAN; STAT1 PROTEIN; STAT1 PROTEIN, HUMAN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR;

ANIMAL; ATOPIC DERMATITIS; CELL LINE; DOWN REGULATION; DRUG EFFECTS; HUMAN; KERATINOCYTE; MACROPHAGE; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION; RAW 264.7 CELL LINE;

ANIMALS; CELL LINE; CHEMOKINE CCL17; CHEMOKINE CCL22; DERMATITIS, ATOPIC; DOWN-REGULATION; GINSENOSIDES; HUMANS; I-KAPPA B KINASE; INTERFERON-GAMMA; KERATINOCYTES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RAW 264.7 CELLS; REACTIVE OXYGEN SPECIES; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84951926734     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-015-9983-y     Document Type: Article

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