메뉴 건너뛰기




Volumn 92, Issue 5, 2018, Pages

Maintenance of AP-2- dependent functional activities of Nef restricts pathways of immune escape from CD8 T lymphocyte responses

Author keywords

CD4; Evolution; Major histocompatibility complex; SERINC; Simian immunodeficiency virus; Tetherin; Viral escape

Indexed keywords

BONE MARROW STROMAL ANTIGEN 2; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; TRANSCRIPTION FACTOR AP 2; CELL SURFACE RECEPTOR; EPITOPE; HLA ANTIGEN CLASS 1; MAMU-B 01 ANTIGEN, MACACA MULATTA; MEMBRANE PROTEIN; NEF PROTEIN, SIV; SERINC3 PROTEIN, HUMAN; SERINC5 PROTEIN, HUMAN; TUMOR PROTEIN; VIRAL PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

EID: 85042035725     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01822-17     Document Type: Article
Times cited : (11)

References (87)
  • 1
    • 0038581912 scopus 로고    scopus 로고
    • The influence of HLA genotype on AIDS
    • Carrington M, O'Brien S. 2003. The influence of HLA genotype on AIDS. Annu Rev Med 54:535-551. https://doi.org/10.1146/annurev .med.54.101601.152346
    • (2003) Annu Rev Med , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.2
  • 2
    • 48749103238 scopus 로고    scopus 로고
    • Impact of MHC class I diversity on immune control of immunodeficiency virus replication
    • Goulder P, Watkins D. 2008. Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat Rev Immunol 8:619-630. https://doi.org/10.1038/nri2357
    • (2008) Nat Rev Immunol , vol.8 , pp. 619-630
    • Goulder, P.1    Watkins, D.2
  • 3
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: implications for vaccine design
    • Goulder P, Watkins D. 2004. HIV and SIV CTL escape: implications for vaccine design. Nat Rev Immunol 4:630-640. https://doi.org/10.1038/ nri1417
    • (2004) Nat Rev Immunol , vol.4 , pp. 630-640
    • Goulder, P.1    Watkins, D.2
  • 7
    • 3543113110 scopus 로고    scopus 로고
    • Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child
    • Feeney M, Tang Y, Roosevelt K, Leslie A, McIntosh K, Karthas N, Walker B, Goulder P. 2004. Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child. J Virol 78:8927-8930. https://doi.org/10.1128/JVI.78.16.8927-8930 .2004
    • (2004) J Virol , vol.78 , pp. 8927-8930
    • Feeney, M.1    Tang, Y.2    Roosevelt, K.3    Leslie, A.4    McIntosh, K.5    Karthas, N.6    Walker, B.7    Goulder, P.8
  • 15
    • 84859406226 scopus 로고    scopus 로고
    • Escape from CD8+ T cell responses in Mamu-B*00801+ macaques differentiates progressors from elite controllers
    • Mudd P, Ericsen A, Burwitz B, Wilson N, O'Connor D, Hughes A, Watkins D. 2012. Escape from CD8+ T cell responses in Mamu-B*00801+ macaques differentiates progressors from elite controllers. J Immunol 188: 3364-3370. https://doi.org/10.4049/jimmunol.1102470
    • (2012) J Immunol , vol.188 , pp. 3364-3370
    • Mudd, P.1    Ericsen, A.2    Burwitz, B.3    Wilson, N.4    O'Connor, D.5    Hughes, A.6    Watkins, D.7
  • 29
    • 84874671204 scopus 로고    scopus 로고
    • Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells
    • Kloverpris H, Payne R, Sacha J, Rasaiyaah J, Chen F, Takiguchi M, Yang O, Towers G, Goulder P, Prado J. 2013. Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells. J Virol 87:2628-2638. https://doi.org/10.1128/JVI.02131-12
    • (2013) J Virol , vol.87 , pp. 2628-2638
    • Kloverpris, H.1    Payne, R.2    Sacha, J.3    Rasaiyaah, J.4    Chen, F.5    Takiguchi, M.6    Yang, O.7    Towers, G.8    Goulder, P.9    Prado, J.10
  • 33
    • 67649172577 scopus 로고    scopus 로고
    • Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity
    • Loffredo J, Sidney J, Bean A, Beal D, Bardet W, Wahl A, Hawkins O, Piaskowski S, Wilson N, Hildebrand W, Watkins D, Sette A. 2009. Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity. J Immunol 182:7763-7775. https://doi.org/10.4049/ jimmunol.0900111
    • (2009) J Immunol , vol.182 , pp. 7763-7775
    • Loffredo, J.1    Sidney, J.2    Bean, A.3    Beal, D.4    Bardet, W.5    Wahl, A.6    Hawkins, O.7    Piaskowski, S.8    Wilson, N.9    Hildebrand, W.10    Watkins, D.11    Sette, A.12
  • 34
    • 0036644216 scopus 로고    scopus 로고
    • Characterization of the peptide-binding specificity of Mamu-B*17 and identification of Mamu-B*17-restricted epitopes derived from simian immunodeficiency virus proteins
    • Mothe B, Sidney J, Dzuris J, Liebl M, Fuenger S, Watkins D, Sette A. 2002. Characterization of the peptide-binding specificity of Mamu-B*17 and identification of Mamu-B*17-restricted epitopes derived from simian immunodeficiency virus proteins. J Immunol 169:210-219. https://doi .org/10.4049/jimmunol.169.1.210
    • (2002) J Immunol , vol.169 , pp. 210-219
    • Mothe, B.1    Sidney, J.2    Dzuris, J.3    Liebl, M.4    Fuenger, S.5    Watkins, D.6    Sette, A.7
  • 37
    • 84897478454 scopus 로고    scopus 로고
    • Characterization of the protective HIV-1 CTL epitopes and the corresponding HLA class I alleles: a step towards designing a CTL-based HIV-1 vaccine
    • Chakraborty S, Rahman T, Chakravorty R. 2014. Characterization of the protective HIV-1 CTL epitopes and the corresponding HLA class I alleles: a step towards designing a CTL-based HIV-1 vaccine. Adv Virol 2014: 321974. https://doi.org/10.1155/2014/321974
    • (2014) Adv Virol , vol.2014
    • Chakraborty, S.1    Rahman, T.2    Chakravorty, R.3
  • 44
    • 0028111663 scopus 로고
    • The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys
    • Ilyinskii PO, Daniel MD, Simon MA, Lackner AA, Desrosiers RC. 1994. The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys. J Virol 68:5933-5944
    • (1994) J Virol , vol.68 , pp. 5933-5944
    • Ilyinskii, P.O.1    Daniel, M.D.2    Simon, M.A.3    Lackner, A.A.4    Desrosiers, R.C.5
  • 45
    • 0025733252 scopus 로고
    • Serine phosphorylation-independent downregulation of cell surface CD4 by nef
    • Garcia JV, Miller AD. 1991. Serine phosphorylation-independent downregulation of cell surface CD4 by nef. Nature 350:508-511. https://doi .org/10.1038/350508a0
    • (1991) Nature , vol.350 , pp. 508-511
    • Garcia, J.V.1    Miller, A.D.2
  • 46
    • 0028308380 scopus 로고
    • Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open
    • Foster JL, Anderson SJ, Frazier AL, Garcia JV. 1994. Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open. Virology 201:373-379. https:// doi.org/10.1006/viro.1994.1303
    • (1994) Virology , vol.201 , pp. 373-379
    • Foster, J.L.1    Anderson, S.J.2    Frazier, A.L.3    Garcia, J.V.4
  • 47
    • 84855918309 scopus 로고    scopus 로고
    • Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins
    • Heigele A, Schindler M, Gnanadurai C, Leonard J, Collins K, Kirchhoff F. 2012. Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins. J Virol 86:36-48. https://doi.org/10 .1128/JVI.00717-11
    • (2012) J Virol , vol.86 , pp. 36-48
    • Heigele, A.1    Schindler, M.2    Gnanadurai, C.3    Leonard, J.4    Collins, K.5    Kirchhoff, F.6
  • 48
    • 0035946302 scopus 로고    scopus 로고
    • Down-modulation of the costimulatory molecule, CD28, is a conserved activity of multiple SIV Nefs and is dependent on histidine 196 of Nef
    • Bell I, Schaefer TM, Trible RP, Amedee A, Reinhart TA. 2001. Down-modulation of the costimulatory molecule, CD28, is a conserved activity of multiple SIV Nefs and is dependent on histidine 196 of Nef. Virology 283:148-158. https://doi.org/10.1006/viro.2001.0872
    • (2001) Virology , vol.283 , pp. 148-158
    • Bell, I.1    Schaefer, T.M.2    Trible, R.P.3    Amedee, A.4    Reinhart, T.A.5
  • 51
    • 0029875421 scopus 로고    scopus 로고
    • Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
    • Schwartz O, Marechal V, Le Gall S, Lemonnier F, Heard J. 1996. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat Med 2:338-342. https://doi .org/10.1038/nm0396-338
    • (1996) Nat Med , vol.2 , pp. 338-342
    • Schwartz, O.1    Marechal, V.2    Le Gall, S.3    Lemonnier, F.4    Heard, J.5
  • 54
    • 25444510358 scopus 로고    scopus 로고
    • The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs
    • Chaudhry A, Das S, Hussain A, Mayor S, George A, Bal V, Jameel S, Rath S. 2005. The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs. J Immunol 175:4566-4574. https://doi.org/10.4049/jimmunol.175.7.4566
    • (2005) J Immunol , vol.175 , pp. 4566-4574
    • Chaudhry, A.1    Das, S.2    Hussain, A.3    Mayor, S.4    George, A.5    Bal, V.6    Jameel, S.7    Rath, S.8
  • 55
    • 85001115546 scopus 로고    scopus 로고
    • The antagonism of HIV-1 Nef to SERINC5 particle infectivity restriction involves the counteraction of virion-associated pools of the restriction factor
    • Trautz B, Pierini V, Wombacher R, Stolp B, Chase AJ, Pizzato M, Fackler OT. 2016. The antagonism of HIV-1 Nef to SERINC5 particle infectivity restriction involves the counteraction of virion-associated pools of the restriction factor. J Virol 90:10915-10927. https://doi.org/10.1128/JVI .01246-16
    • (2016) J Virol , vol.90 , pp. 10915-10927
    • Trautz, B.1    Pierini, V.2    Wombacher, R.3    Stolp, B.4    Chase, A.J.5    Pizzato, M.6    Fackler, O.T.7
  • 56
    • 84944110470 scopus 로고    scopus 로고
    • SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
    • Usami Y, Wu Y, Gottlinger HG. 2015. SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef. Nature 526:218-223. https://doi .org/10.1038/nature15400
    • (2015) Nature , vol.526 , pp. 218-223
    • Usami, Y.1    Wu, Y.2    Gottlinger, H.G.3
  • 59
    • 0030684068 scopus 로고    scopus 로고
    • Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 downregulation
    • Greenberg M, Bronson S, Lock M, Neumann M, Pavlakis G, Skowronski J. 1997. Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 downregulation. EMBO J 16: 6964-6976. https://doi.org/10.1093/emboj/16.23.6964
    • (1997) EMBO J , vol.16 , pp. 6964-6976
    • Greenberg, M.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakis, G.5    Skowronski, J.6
  • 60
    • 0035794535 scopus 로고    scopus 로고
    • Mechanism for down-regulation of CD28 by Nef
    • Swigut T, Shohdy N, Skowronski J. 2001. Mechanism for down-regulation of CD28 by Nef. EMBO J 20:1593-1604. https://doi.org/10.1093/emboj/ 20.7.1593
    • (2001) EMBO J , vol.20 , pp. 1593-1604
    • Swigut, T.1    Shohdy, N.2    Skowronski, J.3
  • 62
    • 79958024908 scopus 로고    scopus 로고
    • SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release
    • Zhang F, Landford W, Ng M, McNatt M, Bieniasz P, Hatziioannou T. 2011. SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release. PLoS Pathog 7:e1002039. https://doi.org/10 .1371/journal.ppat.1002039
    • (2011) PLoS Pathog , vol.7
    • Zhang, F.1    Landford, W.2    Ng, M.3    McNatt, M.4    Bieniasz, P.5    Hatziioannou, T.6
  • 63
    • 84898733948 scopus 로고    scopus 로고
    • How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4
    • Ren X, Park SY, Bonifacino JS, Hurley JH. 2014. How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4. Elife 3:e01754. https://doi .org/10.7554/eLife.01754
    • (2014) Elife , vol.3
    • Ren, X.1    Park, S.Y.2    Bonifacino, J.S.3    Hurley, J.H.4
  • 64
    • 84884769542 scopus 로고    scopus 로고
    • Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis
    • Serra-Moreno R, Zimmermann K, Stern L, Evans D. 2013. Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. PLoS Pathog 9:e1003487. https://doi.org/10.1371/journal.ppat.1003487
    • (2013) PLoS Pathog , vol.9
    • Serra-Moreno, R.1    Zimmermann, K.2    Stern, L.3    Evans, D.4
  • 65
    • 38349109364 scopus 로고    scopus 로고
    • A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2
    • Lindwasser OW, Smith WJ, Chaudhuri R, Yang P, Hurley JH, Bonifacino JS. 2008. A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2. J Virol 82:1166-1174. https://doi .org/10.1128/JVI.01874-07
    • (2008) J Virol , vol.82 , pp. 1166-1174
    • Lindwasser, O.W.1    Smith, W.J.2    Chaudhuri, R.3    Yang, P.4    Hurley, J.H.5    Bonifacino, J.S.6
  • 68
    • 84942155315 scopus 로고    scopus 로고
    • Envelope glycoprotein internalization protects human and simian immunodeficiency virus-infected cells from antibodydependent cell-mediated cytotoxicity
    • von Bredow B, Arias JF, Heyer LN, Gardner MR, Farzan M, Rakasz EG, Evans DT. 2015. Envelope glycoprotein internalization protects human and simian immunodeficiency virus-infected cells from antibodydependent cell-mediated cytotoxicity. J Virol 89:10648-10655. https:// doi.org/10.1128/JVI.01911-15
    • (2015) J Virol , vol.89 , pp. 10648-10655
    • von Bredow, B.1    Arias, J.F.2    Heyer, L.N.3    Gardner, M.R.4    Farzan, M.5    Rakasz, E.G.6    Evans, D.T.7
  • 71
    • 0033780046 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
    • O'Doherty U, Swiggard W, Malim M. 2000. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J Virol 74:10074-10080. https://doi.org/10.1128/JVI.74.21.10074-10080.2000
    • (2000) J Virol , vol.74 , pp. 10074-10080
    • O'Doherty, U.1    Swiggard, W.2    Malim, M.3
  • 72
    • 34247129671 scopus 로고    scopus 로고
    • Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor
    • Chaudhuri R, Lindwasser OW, Smith WJ, Hurley JH, Bonifacino JS. 2007. Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J Virol 81:3877-3890. https://doi.org/10.1128/JVI .02725-06
    • (2007) J Virol , vol.81 , pp. 3877-3890
    • Chaudhuri, R.1    Lindwasser, O.W.2    Smith, W.J.3    Hurley, J.H.4    Bonifacino, J.S.5
  • 73
    • 0347155580 scopus 로고    scopus 로고
    • Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3
    • Rodionov DG, Honing S, Silye A, Kongsvik TL, von Figura K, Bakke O. 2002. Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3. J Biol Chem 277:47436-47443. https://doi.org/10.1074/jbc.M207149200
    • (2002) J Biol Chem , vol.277 , pp. 47436-47443
    • Rodionov, D.G.1    Honing, S.2    Silye, A.3    Kongsvik, T.L.4    von Figura, K.5    Bakke, O.6
  • 74
    • 58149517692 scopus 로고    scopus 로고
    • Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein
    • Prado J, Honeyborne I, Brierley I, Puertas M, Martinez-Picado J, Goulder P. 2009. Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein. J Virol 83:1018-1025. https://doi.org/10.1128/JVI.01882-08
    • (2009) J Virol , vol.83 , pp. 1018-1025
    • Prado, J.1    Honeyborne, I.2    Brierley, I.3    Puertas, M.4    Martinez-Picado, J.5    Goulder, P.6
  • 82
    • 76649115901 scopus 로고    scopus 로고
    • Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies
    • Sacha J, Watkins D. 2010. Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies. Nat Protoc 5:239-246. https://doi.org/10.1038/nprot.2009.227
    • (2010) Nat Protoc , vol.5 , pp. 239-246
    • Sacha, J.1    Watkins, D.2
  • 83
    • 2942661340 scopus 로고    scopus 로고
    • Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity
    • Yuste E, Reeves JD, Doms RW, Desrosiers RC. 2004. Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivity. J Virol 78:6775-6785. https:// doi.org/10.1128/JVI.78.13.6775-6785.2004
    • (2004) J Virol , vol.78 , pp. 6775-6785
    • Yuste, E.1    Reeves, J.D.2    Doms, R.W.3    Desrosiers, R.C.4
  • 84
    • 84916918924 scopus 로고    scopus 로고
    • Systematic analysis of intracellular trafficking motifs located within the cytoplasmic domain of simian immunodeficiency virus glycoprotein gp41
    • Postler TS, Bixby JG, Desrosiers RC, Yuste E. 2014. Systematic analysis of intracellular trafficking motifs located within the cytoplasmic domain of simian immunodeficiency virus glycoprotein gp41. PLoS One 9:e114753. https://doi.org/10.1371/journal.pone.0114753
    • (2014) PLoS One , vol.9
    • Postler, T.S.1    Bixby, J.G.2    Desrosiers, R.C.3    Yuste, E.4
  • 86
    • 79961123152 scopus 로고    scopus 로고
    • RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
    • Li B, Dewey C. 2011. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12:323. https://doi.org/10.1186/1471-2105-12-323
    • (2011) BMC Bioinformatics , vol.12 , pp. 323
    • Li, B.1    Dewey, C.2
  • 87
    • 84891626759 scopus 로고    scopus 로고
    • Optimization of PCR for quantification of simian immunodeficiency virus genomic RNA in plasma of rhesus macaques (Macaca mulatta) using armored RNA
    • Monjure CJ, Tatum CD, Panganiban AT, Arainga M, Traina-Dorge V, Marx PA, Jr, Didier ES. 2014. Optimization of PCR for quantification of simian immunodeficiency virus genomic RNA in plasma of rhesus macaques (Macaca mulatta) using armored RNA. J Med Primatol 43:31-43. https:// doi.org/10.1111/jmp.12088
    • (2014) J Med Primatol , vol.43 , pp. 31-43
    • Monjure, C.J.1    Tatum, C.D.2    Panganiban, A.T.3    Arainga, M.4    Traina-Dorge, V.5    Marx, P.A.6    Didier, E.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.