Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses

Nature Communications

Volumn 4, Issue , 2013, Pages

  Wilker, Peter R ^a,g   Dinis, Jorge M ^a   Starrett, Gabriel ^b   Imai, Masaki ^a   Hatta, Masato ^a   Nelson, Chase W ^c   O'Connor, David H ^b,f   Hughes, Austin L ^c   Neumann, Gabriele ^a   Kawaoka, Yoshihiro ^a,d,e   Friedrich, Thomas C ^a,f  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF SOUTH CAROLINA   (United States)

^d UNIVERSITY OF TOKYO   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f UNIVERSITY OF WISCONSIN   (United States)

^g UNIVERSITY OF WISCONSIN LA CROSSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTININ;

ADAPTATION; EPIDEMIOLOGY; GENETIC VARIATION; INFLUENZA; INOCULATION; MUSTELID; NATURAL SELECTION; POPULATION BOTTLENECK; PROTEIN;

ADAPTATION; ANIMAL EXPERIMENT; ARTICLE; BOTTLENECK POPULATION; FEMALE; FERRET; GENETIC REASSORTMENT; GENETIC VARIABILITY; HOST SELECTION; INFLUENZA VIRUS A H5N1; INOCULATION; NONHUMAN; PARAINFLUENZA VIRUS INFECTION; RNA SEQUENCE; VIRUS REPLICATION; VIRUS TRANSMISSION;

ANIMALIA; AVIAN INFLUENZA VIRUS; MAMMALIA; MUSTELA; ORTHOMYXOVIRIDAE;

ADAPTATION, BIOLOGICAL; ANIMALS; FERRETS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOST SPECIFICITY; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; ORTHOMYXOVIRIDAE INFECTIONS; POLYMORPHISM, SINGLE NUCLEOTIDE; REASSORTANT VIRUSES; SELECTION, GENETIC; SPECIES SPECIFICITY;

EID: 84889263122     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3636     Document Type: Article

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