IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Zhao, Ming ^a   Tan, Yixin ^a   Peng, Qiao ^a   Huang, Cancan ^a   Guo, Yu ^a   Liang, Gongping ^a   Zhu, Bochen ^a   Huang, Yi ^a   Liu, Aiyun ^a   Wang, Zijun ^a   Li, Mengying ^a   Gao, Xiaofei ^a   Wu, Ruifang ^a   Wu, Haijing ^a   Long, Hai ^a   Lu, Qianjin ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; DNA (CYTOSINE 5) METHYLTRANSFERASE 1; HISTONE DEACETYLASE 1; HISTONE H3; INTERLEUKIN 6; MESSENGER RNA; REGULATORY FACTOR X1; STAT3 PROTEIN;

CELL; GENE EXPRESSION; IMMUNE RESPONSE; METHYLATION; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CHROMATIN; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRISTANE-INDUCED LUPUS; PROMOTER REGION; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TH17 CELL; ADOLESCENT; ADULT; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; DRUG EFFECTS; FEMALE; GENETIC EPIGENESIS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; JURKAT CELL LINE; KNOCKOUT MOUSE; MALE; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; YOUNG ADULT;

MUS;

ADOLESCENT; ADULT; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPIGENESIS, GENETIC; FEMALE; HEK293 CELLS; HUMANS; INTERLEUKIN-6; JURKAT CELLS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; PHOSPHORYLATION; REGULATORY FACTOR X1; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS; YOUNG ADULT;

EID: 85041925915     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-02890-0     Document Type: Article

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