Urolithins Attenuate LPS-Induced Neuroinflammation in BV2Microglia via MAPK, Akt, and NF-κB Signaling Pathways

Journal of Agricultural and Food Chemistry

Volumn 66, Issue 3, 2018, Pages 571-580

  Xu, Jialin ^a   Yuan, Chunhui ^a   Wang, Guihua ^a   Luo, Jiaming ^a   Ma, Hang ^b   Xu, Li ^a   Mu, Yu ^a   Li, Yuanyuan ^a   Seeram, Navindra P ^b   Huang, Xueshi ^a   Li, Liya ^a  

^a NORTHEASTERN UNIVERSITY   (China)

^b UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

ellagitannins; microglia; neuroinflammation; urolithins

Indexed keywords

METABOLITES; PIGMENTS;

ELLAGITANNINS; INFLAMMATORY GENES; MICROGLIA; NEUROINFLAMMATION; NEUROPROTECTIVE EFFECTS; NUCLEAR TRANSLOCATIONS; POTENTIAL MECHANISM; UROLITHINS;

PHOSPHORYLATION;

3,8-DIHYDROXY-6H-DIBENZO(B,D)PYRAN-6-ONE; COUMARIN DERIVATIVE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEUROPROTECTIVE AGENT; PROTEIN KINASE B; TANNIN; TUMOR NECROSIS FACTOR; UROLITHIN C;

ANIMAL; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; MICROGLIA; MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; COUMARINS; HYDROLYZABLE TANNINS; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85041106858     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.7b03285     Document Type: Article

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