Nitric oxide synthase inhibitor, aminoguanidine reduces intracerebroventricular colchicine induced neurodegeneration, memory impairments and changes of systemic immune responses in rats

Journal of Neuroimmunology

Volumn 303, Issue , 2017, Pages 51-61

  Sil, Susmita ^a,b   Ghosh, Tusharkanti ^a   Ghosh, Rupsa ^a   Gupta, Pritha ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Aminoguanidine; Colchicine; Neurodegeneration; Neuroinflammation; Systemic immune responses

Indexed keywords

AMINOGUANIDINE; COLCHICINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NITRITE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; ENZYME INHIBITOR; GUANIDINE DERIVATIVE; NOS2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CELL ADHESION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DOSE COMPARISON; ENZYME INHIBITION; HIPPOCAMPAL TISSUE; IMMUNE DEFICIENCY; IMMUNE RESPONSE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LEUKOCYTE; MALE; MEMORY DISORDER; MINIMUM INHIBITORY CONCENTRATION; MONONUCLEAR CELL; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PHAGOCYTOSIS; PLAQUE FORMING CELL; POLYMORPHONUCLEAR CELL; RAT; REFERENCE MEMORY; SPLEEN CELL; WORKING MEMORY; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; HIPPOCAMPUS; IMMUNOLOGY; MEMORY DISORDERS; NEURODEGENERATIVE DISEASES;

ANIMALS; COLCHICINE; ENZYME INHIBITORS; GUANIDINES; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MEMORY DISORDERS; MICE; NEURODEGENERATIVE DISEASES; NITRIC OXIDE SYNTHASE TYPE II; RATS;

EID: 85008477437     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2016.12.007     Document Type: Article

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