Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia

International Immunopharmacology

Volumn 10, Issue 8, 2010, Pages 883-891

  Lin, Hsiao Yun ^a   Tang, Chih Hsin ^a   Chen, Yi Hung ^a   Wei, I Hua ^a   Chen, Jia Hong ^a,b   Lai, Chih Ho ^a,c   Lu, Dah Yuu ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

COX 2; INOS; Microglia; NF B; Peptidoglycan

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CYCLOOXYGENASE 2; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PEPTIDOGLYCAN; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P85; PYRROLIDINE DITHIOCARBAMATE; SERINE; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 2; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANDROSTADIENES; ANIMALS; ANTIBODIES, BLOCKING; CELL LINE, TRANSFORMED; CHROMONES; CYCLOOXYGENASE 2; CYTOKINES; INFLAMMATION MEDIATORS; MICE; MICROGLIA; MORPHOLINES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDOGLYCAN; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2;

EID: 77954956788     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.04.026     Document Type: Article

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