메뉴 건너뛰기




Volumn 822, Issue , 2018, Pages 25-31

Sodium–glucose transporter as a novel therapeutic target in disease

Author keywords

Cancer; Cardiac disease; Cerebral ischemia; Intestinal ischemia; SGLT

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; SODIUM GLUCOSE COTRANSPORTER; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 3; SODIUM ION; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 85040698843     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2018.01.003     Document Type: Review
Times cited : (20)

References (99)
  • 1
    • 70449729537 scopus 로고    scopus 로고
    • SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states
    • Banerjee, S.K., McGaffin, K.R., Pastor-Soler, N.M., Ahmad, F., SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states. Cardiovasc. Res. 84 (2009), 111–118.
    • (2009) Cardiovasc. Res. , vol.84 , pp. 111-118
    • Banerjee, S.K.1    McGaffin, K.R.2    Pastor-Soler, N.M.3    Ahmad, F.4
  • 2
    • 0001055273 scopus 로고
    • Diminished pain in diabetic patients with acute myocardial infarction
    • Bradley, R.F., Schonfeld, A., Diminished pain in diabetic patients with acute myocardial infarction. Geriatrics 17 (1962), 322–326.
    • (1962) Geriatrics , vol.17 , pp. 322-326
    • Bradley, R.F.1    Schonfeld, A.2
  • 3
    • 0027489912 scopus 로고
    • Overexpression of glut‐1 glucose transporter in human breast cancer an immunohistochemical study
    • Brown, R.S., Wahl, R.L., Overexpression of glut‐1 glucose transporter in human breast cancer an immunohistochemical study. Cancer 72 (1993), 2979–2985.
    • (1993) Cancer , vol.72 , pp. 2979-2985
    • Brown, R.S.1    Wahl, R.L.2
  • 5
    • 0034800666 scopus 로고    scopus 로고
    • Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview
    • Capes, S.E., Hunt, D., Malmberg, K., Pathak, P., Gerstein, H.C., Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke 32 (2001), 2426–2432.
    • (2001) Stroke , vol.32 , pp. 2426-2432
    • Capes, S.E.1    Hunt, D.2    Malmberg, K.3    Pathak, P.4    Gerstein, H.C.5
  • 6
    • 84937966992 scopus 로고    scopus 로고
    • Co-option of developmentally regulated plant SWEET transporters for pathogen nutrition and abiotic stress tolerance
    • Chandran, D., Co-option of developmentally regulated plant SWEET transporters for pathogen nutrition and abiotic stress tolerance. IUBMB Life 67 (2015), 461–471.
    • (2015) IUBMB Life , vol.67 , pp. 461-471
    • Chandran, D.1
  • 7
    • 84930632695 scopus 로고    scopus 로고
    • Global proteomic analysis of brain tissues in transient ischemia brain damage in rats
    • Chen, J.-H., Kuo, H.-C., Lee, K.-F., Tsai, T.-H., Global proteomic analysis of brain tissues in transient ischemia brain damage in rats. Int. J. Mol. Sci. 16 (2015), 11873–11891.
    • (2015) Int. J. Mol. Sci. , vol.16 , pp. 11873-11891
    • Chen, J.-H.1    Kuo, H.-C.2    Lee, K.-F.3    Tsai, T.-H.4
  • 9
    • 84985990097 scopus 로고    scopus 로고
    • High glucose-induced oxidative stress mediates apoptosis and extracellular matrix metabolic imbalances possibly via p38 MAPK activation in rat nucleus pulposus cells
    • Cheng, X., Ni, B., Zhang, F., Hu, Y., Zhao, J., High glucose-induced oxidative stress mediates apoptosis and extracellular matrix metabolic imbalances possibly via p38 MAPK activation in rat nucleus pulposus cells. J. Diabetes Res., 2016, 2016, 3765173.
    • (2016) J. Diabetes Res. , vol.2016 , pp. 3765173
    • Cheng, X.1    Ni, B.2    Zhang, F.3    Hu, Y.4    Zhao, J.5
  • 11
    • 33845992169 scopus 로고    scopus 로고
    • Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment
    • Danaei, G., Lawes, C.M., Vander Hoorn, S., Murray, C.J., Ezzati, M., Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. Lancet 368 (2006), 1651–1659.
    • (2006) Lancet , vol.368 , pp. 1651-1659
    • Danaei, G.1    Lawes, C.M.2    Vander Hoorn, S.3    Murray, C.J.4    Ezzati, M.5
  • 12
    • 85016021198 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter 2 inhibition: cardioprotection by treating diabetes-a translational viewpoint explaining its potential salutary effects
    • de Leeuw, A.E., de Boer, R.A., Sodium-glucose cotransporter 2 inhibition: cardioprotection by treating diabetes-a translational viewpoint explaining its potential salutary effects. Eur. Hear J. Cardiovasc. Pharmacother. 2 (2016), 244–255.
    • (2016) Eur. Hear J. Cardiovasc. Pharmacother. , vol.2 , pp. 244-255
    • de Leeuw, A.E.1    de Boer, R.A.2
  • 13
    • 77449118127 scopus 로고    scopus 로고
    • Impact of glucose tolerance status on development of ischemic stroke and coronary heart disease in a general Japanese population: the Hisayama study
    • Doi, Y., Ninomiya, T., Hata, J., Fukuhara, M., Yonemoto, K., Iwase, M., Iida, M., Kiyohara, Y., Impact of glucose tolerance status on development of ischemic stroke and coronary heart disease in a general Japanese population: the Hisayama study. Stroke 41 (2010), 203–209.
    • (2010) Stroke , vol.41 , pp. 203-209
    • Doi, Y.1    Ninomiya, T.2    Hata, J.3    Fukuhara, M.4    Yonemoto, K.5    Iwase, M.6    Iida, M.7    Kiyohara, Y.8
  • 14
    • 79953757268 scopus 로고    scopus 로고
    • The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease
    • Dreier, J.P., The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat. Med. 17 (2011), 439–447.
    • (2011) Nat. Med. , vol.17 , pp. 439-447
    • Dreier, J.P.1
  • 15
    • 84938997960 scopus 로고    scopus 로고
    • A validation study of the use of near-infrared spectroscopy imaging in primary and secondary motor areas of the human brain
    • Drenckhahn, C., Koch, S.P., Dümmler, J., Kohl-Bareis, M., Steinbrink, J., Dreier, J.P., A validation study of the use of near-infrared spectroscopy imaging in primary and secondary motor areas of the human brain. Epilepsy Behav. 49 (2015), 118–125.
    • (2015) Epilepsy Behav. , vol.49 , pp. 118-125
    • Drenckhahn, C.1    Koch, S.P.2    Dümmler, J.3    Kohl-Bareis, M.4    Steinbrink, J.5    Dreier, J.P.6
  • 18
    • 84879692789 scopus 로고    scopus 로고
    • Antioxidant supplementation has a positive effect on oxidative stress and hematological toxicity during oncology treatment in cervical cancer patients
    • Fuchs-Tarlovsky, V., Rivera, M.A.C., Altamirano, K.A., Lopez-Alvarenga, J.C., Ceballos-Reyes, G.M., Antioxidant supplementation has a positive effect on oxidative stress and hematological toxicity during oncology treatment in cervical cancer patients. Support. Care Cancer 21 (2013), 1359–1363.
    • (2013) Support. Care Cancer , vol.21 , pp. 1359-1363
    • Fuchs-Tarlovsky, V.1    Rivera, M.A.C.2    Altamirano, K.A.3    Lopez-Alvarenga, J.C.4    Ceballos-Reyes, G.M.5
  • 20
    • 78649410244 scopus 로고    scopus 로고
    • Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice
    • Fung, C., Evans, E., Shin, D., Shin, B.-C., Zhao, Y., Sankar, R., Chaudhuri, G., Devaskar, S.U., Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. J. Neurosci. Res. 88 (2010), 3386–3398.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 3386-3398
    • Fung, C.1    Evans, E.2    Shin, D.3    Shin, B.-C.4    Zhao, Y.5    Sankar, R.6    Chaudhuri, G.7    Devaskar, S.U.8
  • 21
    • 31544480399 scopus 로고    scopus 로고
    • Decreased mortality by normalizing blood glucose after acute ischemic stroke
    • Gentile, N.T., Seftchick, M.W., Huynh, T., Kruus, L.K., Gaughan, J., Decreased mortality by normalizing blood glucose after acute ischemic stroke. Acad. Emerg. Med. 13 (2006), 174–180.
    • (2006) Acad. Emerg. Med. , vol.13 , pp. 174-180
    • Gentile, N.T.1    Seftchick, M.W.2    Huynh, T.3    Kruus, L.K.4    Gaughan, J.5
  • 22
    • 84916889897 scopus 로고    scopus 로고
    • Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia
    • Grell, A.-S., Thigarajah, R., Edvinsson, L., Samraj, A.K., Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia. PLoS One, 9, 2014, e113624.
    • (2014) PLoS One , vol.9 , pp. e113624
    • Grell, A.-S.1    Thigarajah, R.2    Edvinsson, L.3    Samraj, A.K.4
  • 23
    • 84856212857 scopus 로고    scopus 로고
    • Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter
    • Grempler, R., Augustin, R., Froehner, S., Hildebrandt, T., Simon, E., Mark, M., Eickelmann, P., Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter. FEBS Lett. 586 (2012), 248–253.
    • (2012) FEBS Lett. , vol.586 , pp. 248-253
    • Grempler, R.1    Augustin, R.2    Froehner, S.3    Hildebrandt, T.4    Simon, E.5    Mark, M.6    Eickelmann, P.7
  • 24
    • 0141532690 scopus 로고    scopus 로고
    • A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line
    • Gribble, F.M., Williams, L., Simpson, A.K., Reimann, F., A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line. Diabetes 52 (2003), 1147–1154.
    • (2003) Diabetes , vol.52 , pp. 1147-1154
    • Gribble, F.M.1    Williams, L.2    Simpson, A.K.3    Reimann, F.4
  • 26
    • 84891808975 scopus 로고    scopus 로고
    • Repression of integrin-linked kinase by antidiabetes drugs through cross-talk of PPARγ- and AMPKα-dependent signaling: role of AP-2α and Sp1
    • Hahn, S.S., Tang, Q., Zheng, F., Zhao, S., Wu, J., Chen, J., Repression of integrin-linked kinase by antidiabetes drugs through cross-talk of PPARγ- and AMPKα-dependent signaling: role of AP-2α and Sp1. Cell Signal. 26 (2014), 639–647.
    • (2014) Cell Signal. , vol.26 , pp. 639-647
    • Hahn, S.S.1    Tang, Q.2    Zheng, F.3    Zhao, S.4    Wu, J.5    Chen, J.6
  • 27
    • 77956179356 scopus 로고    scopus 로고
    • The importance of regulation of blood glucose levels through activation of peripheral 5’-AMP-activated protein kinase on ischemic neuronal damage
    • Harada, S., Fujita-Hamabe, W., Tokuyama, S., The importance of regulation of blood glucose levels through activation of peripheral 5’-AMP-activated protein kinase on ischemic neuronal damage. Brain Res. 1351 (2010), 254–263.
    • (2010) Brain Res. , vol.1351 , pp. 254-263
    • Harada, S.1    Fujita-Hamabe, W.2    Tokuyama, S.3
  • 28
    • 79952333129 scopus 로고    scopus 로고
    • Effect of orexin-A on post-ischemic glucose intolerance and neuronal damage
    • Harada, S., Fujita-Hamabe, W., Tokuyama, S., Effect of orexin-A on post-ischemic glucose intolerance and neuronal damage. J. Pharmacol. Sci. 115 (2011), 155–163.
    • (2011) J. Pharmacol. Sci. , vol.115 , pp. 155-163
    • Harada, S.1    Fujita-Hamabe, W.2    Tokuyama, S.3
  • 29
    • 67649392260 scopus 로고    scopus 로고
    • The development of glucose intolerance after focal cerebral ischemia participates in subsequent neuronal damage
    • Harada, S., Fujita, W.H., Shichi, K., Tokuyama, S., The development of glucose intolerance after focal cerebral ischemia participates in subsequent neuronal damage. Brain Res. 1279 (2009), 174–181.
    • (2009) Brain Res. , vol.1279 , pp. 174-181
    • Harada, S.1    Fujita, W.H.2    Shichi, K.3    Tokuyama, S.4
  • 30
    • 0036704078 scopus 로고    scopus 로고
    • Effects of stimulating the nucleus basalis of Meynert on blood flow and delayed neuronal death following transient ischemia in the rat cerebral cortex
    • Hotta, H., Uchida, S., Kagitani, F., Effects of stimulating the nucleus basalis of Meynert on blood flow and delayed neuronal death following transient ischemia in the rat cerebral cortex. Jpn. J. Physiol. 52 (2002), 383–393.
    • (2002) Jpn. J. Physiol. , vol.52 , pp. 383-393
    • Hotta, H.1    Uchida, S.2    Kagitani, F.3
  • 31
    • 79551587397 scopus 로고    scopus 로고
    • Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia
    • Huang, C.-Y., Hsiao, J.-K., Lu, Y.-Z., Lee, T.-C., Yu, L.C.-H., Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia. Lab. Investig. 91 (2011), 294–309.
    • (2011) Lab. Investig. , vol.91 , pp. 294-309
    • Huang, C.-Y.1    Hsiao, J.-K.2    Lu, Y.-Z.3    Lee, T.-C.4    Yu, L.C.-H.5
  • 32
    • 84861817534 scopus 로고    scopus 로고
    • EGFR-mediated stimulation of sodium/glucose cotransport promotes survival of irradiated human A549 lung adenocarcinoma cells
    • Huber, S.M., Misovic, M., Mayer, C., Rodemann, H.-P., Dittmann, K., EGFR-mediated stimulation of sodium/glucose cotransport promotes survival of irradiated human A549 lung adenocarcinoma cells. Radiother. Oncol. 103 (2012), 373–379.
    • (2012) Radiother. Oncol. , vol.103 , pp. 373-379
    • Huber, S.M.1    Misovic, M.2    Mayer, C.3    Rodemann, H.-P.4    Dittmann, K.5
  • 33
    • 0034820481 scopus 로고    scopus 로고
    • SGLT gene expression in primary lung cancers and their metastatic lesions
    • Ishikawa, N., Oguri, T., Isobe, T., Fujitaka, K., Kohno, N., SGLT gene expression in primary lung cancers and their metastatic lesions. Jpn. J. Cancer Res. 92 (2001), 874–879.
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 874-879
    • Ishikawa, N.1    Oguri, T.2    Isobe, T.3    Fujitaka, K.4    Kohno, N.5
  • 34
    • 84908068614 scopus 로고    scopus 로고
    • Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation
    • Jiang, M., Li, J., Peng, Q., Liu, Y., Liu, W., Luo, C., Peng, J., Li, J., Yung, K.K.L., Mo, Z., Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation. J. Neuroinflamm., 11, 2014, 167.
    • (2014) J. Neuroinflamm. , vol.11 , pp. 167
    • Jiang, M.1    Li, J.2    Peng, Q.3    Liu, Y.4    Liu, W.5    Luo, C.6    Peng, J.7    Li, J.8    Yung, K.K.L.9    Mo, Z.10
  • 35
    • 84979220732 scopus 로고    scopus 로고
    • Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes
    • Jojima, T., Tomotsune, T., Iijima, T., Akimoto, K., Suzuki, K., Aso, Y., Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes. Diabetol. Metab. Syndr., 8, 2016, 45.
    • (2016) Diabetol. Metab. Syndr. , vol.8 , pp. 45
    • Jojima, T.1    Tomotsune, T.2    Iijima, T.3    Akimoto, K.4    Suzuki, K.5    Aso, Y.6
  • 36
    • 84938710060 scopus 로고    scopus 로고
    • Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by phlorizin during ischemia-reperfusion injury in mice
    • Kashiwagi, Y., Nagoshi, T., Yoshino, T., Tanaka, T.D., Ito, K., Harada, T., Takahashi, H., Ikegami, M., Anzawa, R., Yoshimura, M., Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by phlorizin during ischemia-reperfusion injury in mice. PLoS One, 10, 2015, e0130605.
    • (2015) PLoS One , vol.10 , pp. e0130605
    • Kashiwagi, Y.1    Nagoshi, T.2    Yoshino, T.3    Tanaka, T.D.4    Ito, K.5    Harada, T.6    Takahashi, H.7    Ikegami, M.8    Anzawa, R.9    Yoshimura, M.10
  • 37
    • 84930208576 scopus 로고    scopus 로고
    • Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells
    • Kiss, K., Baghy, K., Spisák, S., Szanyi, S., Tulassay, Z., Zalatnai, A., Löhr, J.-M., Jesenofsky, R., Kovalszky, I., Firneisz, G., Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells. PLoS One, 10, 2015, e0128059.
    • (2015) PLoS One , vol.10 , pp. e0128059
    • Kiss, K.1    Baghy, K.2    Spisák, S.3    Szanyi, S.4    Tulassay, Z.5    Zalatnai, A.6    Löhr, J.-M.7    Jesenofsky, R.8    Kovalszky, I.9    Firneisz, G.10
  • 38
    • 79957969635 scopus 로고    scopus 로고
    • Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide
    • Koizumi, H., Fujisawa, H., Suehiro, E., Shirao, S., Suzuki, M., Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide. Neurol. Med. Chir. (Tokyo) 51 (2011), 337–343.
    • (2011) Neurol. Med. Chir. (Tokyo) , vol.51 , pp. 337-343
    • Koizumi, H.1    Fujisawa, H.2    Suehiro, E.3    Shirao, S.4    Suzuki, M.5
  • 39
    • 84877922239 scopus 로고    scopus 로고
    • Ipragliflozin and other sodium?Glucose cotransporter-2 (SGLT2) inhibitors in the treatment of type 2 diabetes: preclinical and clinical data
    • Kurosaki, E., Ogasawara, H., Ipragliflozin and other sodium?Glucose cotransporter-2 (SGLT2) inhibitors in the treatment of type 2 diabetes: preclinical and clinical data. Pharmacol. Ther. 139 (2013), 51–59.
    • (2013) Pharmacol. Ther. , vol.139 , pp. 51-59
    • Kurosaki, E.1    Ogasawara, H.2
  • 40
    • 77951528072 scopus 로고    scopus 로고
    • Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β Snail1, and β-catenin in renal proximal tubule cells
    • Lee, Y.J., Han, H.J., Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β Snail1, and β-catenin in renal proximal tubule cells. Am. J. Physiol. Ren. Physiol. 298 (2010), 1263–1275.
    • (2010) Am. J. Physiol. Ren. Physiol. , vol.298 , pp. 1263-1275
    • Lee, Y.J.1    Han, H.J.2
  • 41
    • 66449084704 scopus 로고    scopus 로고
    • Effect of BSA-induced ER stress on SGLT protein expression levels and alpha-MG uptake in renal proximal tubule cells
    • Lee, Y.J., Suh, H.N., Han, H.J., Effect of BSA-induced ER stress on SGLT protein expression levels and alpha-MG uptake in renal proximal tubule cells. Am. J. Physiol. Ren. Physiol. 296 (2009), 1405–1416.
    • (2009) Am. J. Physiol. Ren. Physiol. , vol.296 , pp. 1405-1416
    • Lee, Y.J.1    Suh, H.N.2    Han, H.J.3
  • 42
    • 77649271004 scopus 로고    scopus 로고
    • Effects of AMP-activated protein kinase in cerebral ischemia
    • Li, J., McCullough, L.D., Effects of AMP-activated protein kinase in cerebral ischemia. J. Cereb. Blood Flow Metab. 30 (2010), 480–492.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 480-492
    • Li, J.1    McCullough, L.D.2
  • 43
    • 74149085909 scopus 로고    scopus 로고
    • Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus
    • Li, S.-Y., Jia, Y.-H., Sun, W.-G., Tang, Y., An, G.-S., Ni, J.-H., Jia, H.-T., Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus. Free Radic. Biol. Med. 48 (2010), 597–608.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 597-608
    • Li, S.-Y.1    Jia, Y.-H.2    Sun, W.-G.3    Tang, Y.4    An, G.-S.5    Ni, J.-H.6    Jia, H.-T.7
  • 44
    • 58049097210 scopus 로고    scopus 로고
    • Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells
    • Lin, X., Ma, L., Fitzgerald, R.L., Ostlund, R.E., Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells. Arch. Biochem. Biophys. 481 (2009), 197–201.
    • (2009) Arch. Biochem. Biophys. , vol.481 , pp. 197-201
    • Lin, X.1    Ma, L.2    Fitzgerald, R.L.3    Ostlund, R.E.4
  • 47
    • 0031887925 scopus 로고    scopus 로고
    • +-dependent and phlorizin-inhibitable transport of glucose and cycasin in brain endothelial cells
    • +-dependent and phlorizin-inhibitable transport of glucose and cycasin in brain endothelial cells. J. Neurochem. 70 (1998), 772–777.
    • (1998) J. Neurochem. , vol.70 , pp. 772-777
    • Matsuoka, T.1    Nishizaki, T.2    Kisby, G.E.3
  • 48
  • 50
    • 84875135352 scopus 로고    scopus 로고
    • The SLC2 (GLUT) family of membrane transporters
    • Mueckler, M., Thorens, B., The SLC2 (GLUT) family of membrane transporters. Mol. Asp. Med. 34 (2013), 121–138.
    • (2013) Mol. Asp. Med. , vol.34 , pp. 121-138
    • Mueckler, M.1    Thorens, B.2
  • 51
    • 39549116502 scopus 로고    scopus 로고
    • Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines
    • Murphy, T.H., Li, P., Betts, K., Liu, R., Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines. J. Neurosci. 28 (2008), 1756–1772.
    • (2008) J. Neurosci. , vol.28 , pp. 1756-1772
    • Murphy, T.H.1    Li, P.2    Betts, K.3    Liu, R.4
  • 53
    • 0027483861 scopus 로고
    • Expression of facilitative glucose transporter isoforms in human brain tumors
    • Nagamatsu, S., Sawa, H., Wakizaka, A., Hoshino, T., Expression of facilitative glucose transporter isoforms in human brain tumors. J. Neurochem. 61 (1993), 2048–2053.
    • (1993) J. Neurochem. , vol.61 , pp. 2048-2053
    • Nagamatsu, S.1    Sawa, H.2    Wakizaka, A.3    Hoshino, T.4
  • 54
    • 68649104009 scopus 로고    scopus 로고
    • Mitochondrial calcium function and dysfunction in the central nervous system
    • Nicholls, D.G., Mitochondrial calcium function and dysfunction in the central nervous system. Biochim. Biophys. Acta 1787 (2009), 1416–1424.
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 1416-1424
    • Nicholls, D.G.1
  • 55
    • 33845516690 scopus 로고    scopus 로고
    • Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing
    • O'Malley, D., Reimann, F., Simpson, A.K., Gribble, F.M., Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing. Diabetes 55 (2006), 3381–3386.
    • (2006) Diabetes , vol.55 , pp. 3381-3386
    • O'Malley, D.1    Reimann, F.2    Simpson, A.K.3    Gribble, F.M.4
  • 58
    • 0025253351 scopus 로고
    • Prognosis after stroke in diabetic patients. A controlled prospective study
    • Olsson, T., Viitanen, M., Asplund, K., Eriksson, S., Hägg, E., Prognosis after stroke in diabetic patients. A controlled prospective study. Diabetologia 33 (1990), 244–249.
    • (1990) Diabetologia , vol.33 , pp. 244-249
    • Olsson, T.1    Viitanen, M.2    Asplund, K.3    Eriksson, S.4    Hägg, E.5
  • 63
    • 78649915745 scopus 로고    scopus 로고
    • [Sodium-glucose cotransporter type 2 inhibitors (SGLT2): from familial renal glucosuria to the treatment of type 2 diabetes mellitus]
    • Pérez López, G., González Albarrán, O., Cano Megías, M., [Sodium-glucose cotransporter type 2 inhibitors (SGLT2): from familial renal glucosuria to the treatment of type 2 diabetes mellitus]. Nefrologia 30 (2010), 618–625.
    • (2010) Nefrologia , vol.30 , pp. 618-625
    • Pérez López, G.1    González Albarrán, O.2    Cano Megías, M.3
  • 64
    • 84941934888 scopus 로고    scopus 로고
    • Risk of and risk factors for hypoglycemia and associated arrhythmias in patients with type 2 diabetes and cardiovascular disease: a cohort study under real-world conditions
    • Pistrosch, F., Ganz, X., Bornstein, S.R., Birkenfeld, A.L., Henkel, E., Hanefeld, M., Risk of and risk factors for hypoglycemia and associated arrhythmias in patients with type 2 diabetes and cardiovascular disease: a cohort study under real-world conditions. Acta Diabetol. 52 (2015), 889–895.
    • (2015) Acta Diabetol. , vol.52 , pp. 889-895
    • Pistrosch, F.1    Ganz, X.2    Bornstein, S.R.3    Birkenfeld, A.L.4    Henkel, E.5    Hanefeld, M.6
  • 66
    • 84921312956 scopus 로고    scopus 로고
    • Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice
    • Ramratnam, M., Sharma, R.K., D'Auria, S., Lee, S.J., Wang, D., Huang, X.Y.N., Ahmad, F., Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice. J. Am. Heart Assoc., 3, 2014, e000899.
    • (2014) J. Am. Heart Assoc. , vol.3 , pp. e000899
    • Ramratnam, M.1    Sharma, R.K.2    D'Auria, S.3    Lee, S.J.4    Wang, D.5    Huang, X.Y.N.6    Ahmad, F.7
  • 68
    • 33745252164 scopus 로고    scopus 로고
    • Cerebral ischemia-induced apoptosis and necrosis in normal and diabetic rats: effects of insulin and C-peptide
    • Rizk, N.N., Rafols, J.A., Dunbar, J.C., Cerebral ischemia-induced apoptosis and necrosis in normal and diabetic rats: effects of insulin and C-peptide. Brain Res. 1096 (2006), 204–212.
    • (2006) Brain Res. , vol.1096 , pp. 204-212
    • Rizk, N.N.1    Rafols, J.A.2    Dunbar, J.C.3
  • 70
    • 4344559467 scopus 로고    scopus 로고
    • The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function
    • Scheepers, A., Joost, H.-G., Schürmann, A., The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. JPEN J. Parenter. Enter. Nutr. 28 (2004), 364–371.
    • (2004) JPEN J. Parenter. Enter. Nutr. , vol.28 , pp. 364-371
    • Scheepers, A.1    Joost, H.-G.2    Schürmann, A.3
  • 71
    • 4344559467 scopus 로고    scopus 로고
    • The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function
    • Scheepers, A., Joost, H., Schurmann, A., The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. J. Parenter. Enter. Nutr. 28 (2004), 364–371.
    • (2004) J. Parenter. Enter. Nutr. , vol.28 , pp. 364-371
    • Scheepers, A.1    Joost, H.2    Schurmann, A.3
  • 74
    • 84988963310 scopus 로고    scopus 로고
    • Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways
    • Su, L., Du, H., Dong, X., Zhang, X., Lou, Z., Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways. J. Clin. Biochem. Nutr. 59 (2016), 86–92.
    • (2016) J. Clin. Biochem. Nutr. , vol.59 , pp. 86-92
    • Su, L.1    Du, H.2    Dong, X.3    Zhang, X.4    Lou, Z.5
  • 76
    • 84991387225 scopus 로고    scopus 로고
    • Characterization and comparison of sodium-glucose cotransporter 2 inhibitors: part 2. Antidiabetic effects in type 2 diabetic mice
    • Tahara, A., Takasu, T., Yokono, M., Imamura, M., Kurosaki, E., Characterization and comparison of sodium-glucose cotransporter 2 inhibitors: part 2. Antidiabetic effects in type 2 diabetic mice. J. Pharmacol. Sci. 131 (2016), 198–208.
    • (2016) J. Pharmacol. Sci. , vol.131 , pp. 198-208
    • Tahara, A.1    Takasu, T.2    Yokono, M.3    Imamura, M.4    Kurosaki, E.5
  • 78
    • 85014879816 scopus 로고    scopus 로고
    • EGFR induces DNA decomposition via phosphodiester bond cleavage
    • Tong, Y., Li, S., Huang, C., EGFR induces DNA decomposition via phosphodiester bond cleavage. Sci. Rep., 7, 2017, 43698.
    • (2017) Sci. Rep. , vol.7 , pp. 43698
    • Tong, Y.1    Li, S.2    Huang, C.3
  • 79
    • 0025891622 scopus 로고
    • Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter
    • Turk, E., Zabel, B., Mundlos, S., Dyer, J., Wright, E.M., Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter. Nature 350 (1991), 354–356.
    • (1991) Nature , vol.350 , pp. 354-356
    • Turk, E.1    Zabel, B.2    Mundlos, S.3    Dyer, J.4    Wright, E.M.5
  • 80
    • 59649102234 scopus 로고    scopus 로고
    • A functional role for sodium-dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation
    • Vemula, S., Roder, K.E., Yang, T., Bhat, G.J., Thekkumkara, T.J., Abbruscato, T.J., A functional role for sodium-dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation. J. Pharmacol. Exp. Ther. 328 (2009), 487–495.
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 487-495
    • Vemula, S.1    Roder, K.E.2    Yang, T.3    Bhat, G.J.4    Thekkumkara, T.J.5    Abbruscato, T.J.6
  • 81
    • 84964897040 scopus 로고    scopus 로고
    • Reversal of the detrimental effects of post-stroke social isolation by pair-housing is mediated by activation of BDNF-MAPK/ERK in aged mice
    • Verma, R., Harris, N.M., Friedler, B.D., Crapser, J., Patel, A.R., Venna, V., McCullough, L.D., Reversal of the detrimental effects of post-stroke social isolation by pair-housing is mediated by activation of BDNF-MAPK/ERK in aged mice. Sci. Rep., 6, 2016, 25176.
    • (2016) Sci. Rep. , vol.6 , pp. 25176
    • Verma, R.1    Harris, N.M.2    Friedler, B.D.3    Crapser, J.4    Patel, A.R.5    Venna, V.6    McCullough, L.D.7
  • 82
    • 78650864055 scopus 로고    scopus 로고
    • Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke
    • Wang, Y., Denisova, J.V., Kang, K.S., Fontes, J.D., Zhu, B.T., Belousov, A.B., Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke. J. Neurophysiol. 104 (2010), 3551–3556.
    • (2010) J. Neurophysiol. , vol.104 , pp. 3551-3556
    • Wang, Y.1    Denisova, J.V.2    Kang, K.S.3    Fontes, J.D.4    Zhu, B.T.5    Belousov, A.B.6
  • 83
    • 33846023326 scopus 로고    scopus 로고
    • Active sugar transport in health and disease
    • Wright, E.M., Hirayama, B.A., Loo, D.F., Active sugar transport in health and disease. J. Int. Med. 261 (2007), 32–43.
    • (2007) J. Int. Med. , vol.261 , pp. 32-43
    • Wright, E.M.1    Hirayama, B.A.2    Loo, D.F.3
  • 84
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • Wright, E.M., Loo, D.D.F., Hirayama, B.A., Biology of human sodium glucose transporters. Physiol. Rev. 91 (2011), 733–794.
    • (2011) Physiol. Rev. , vol.91 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.F.2    Hirayama, B.A.3
  • 85
    • 1242272759 scopus 로고    scopus 로고
    • The sodium/glucose cotransport family SLC5
    • Wright, E.M., Turk, E., The sodium/glucose cotransport family SLC5. Pflug. Arch. 447 (2004), 510–518.
    • (2004) Pflug. Arch. , vol.447 , pp. 510-518
    • Wright, E.M.1    Turk, E.2
  • 86
    • 84906707091 scopus 로고    scopus 로고
    • Effects of ursolic acid derivatives on Caco-2 cells and their alleviating role in streptozocin-induced Type 2 diabetic rats
    • Wu, P., He, P., Zhao, S., Huang, T., Lu, Y., Zhang, K., Effects of ursolic acid derivatives on Caco-2 cells and their alleviating role in streptozocin-induced Type 2 diabetic rats. Molecules 19 (2014), 12559–12576.
    • (2014) Molecules , vol.19 , pp. 12559-12576
    • Wu, P.1    He, P.2    Zhao, S.3    Huang, T.4    Lu, Y.5    Zhang, K.6
  • 87
    • 85017621001 scopus 로고    scopus 로고
    • Transcription factor SP1 mediates hyperglycemia-induced upregulation of roundabout4 in retinal microvascular endothelial cells
    • Xie, J., Gong, Q., Liu, X., Liu, Z., Tian, R., Cheng, Y., Su, G., Transcription factor SP1 mediates hyperglycemia-induced upregulation of roundabout4 in retinal microvascular endothelial cells. Gene 616 (2017), 31–40.
    • (2017) Gene , vol.616 , pp. 31-40
    • Xie, J.1    Gong, Q.2    Liu, X.3    Liu, Z.4    Tian, R.5    Cheng, Y.6    Su, G.7
  • 88
    • 84908518650 scopus 로고    scopus 로고
    • Prolonged deficits in parvalbumin neuron stimulation-evoked network activity despite recovery of dendritic structure and excitability in the somatosensory cortex following global ischemia in mice
    • Xie, Y., Chen, S., Wu, Y., Murphy, T.H., Prolonged deficits in parvalbumin neuron stimulation-evoked network activity despite recovery of dendritic structure and excitability in the somatosensory cortex following global ischemia in mice. J. Neurosci. 34 (2014), 14890–14900.
    • (2014) J. Neurosci. , vol.34 , pp. 14890-14900
    • Xie, Y.1    Chen, S.2    Wu, Y.3    Murphy, T.H.4
  • 89
    • 85040686065 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase and p38 after cerebral ischemia upregulates cerebral sodium-glucose transporter type 1
    • in press
    • Yamazaki, Y., Arita, K., Harada, S., Tokuyama, S., Activation of c-Jun N-terminal kinase and p38 after cerebral ischemia upregulates cerebral sodium-glucose transporter type 1. J. Pharmacol. Sci., 2018 in press.
    • (2018) J. Pharmacol. Sci.
    • Yamazaki, Y.1    Arita, K.2    Harada, S.3    Tokuyama, S.4
  • 90
    • 84869487801 scopus 로고    scopus 로고
    • Post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage through the cerebral sodium-glucose transporter
    • Yamazaki, Y., Harada, S., Tokuyama, S., Post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage through the cerebral sodium-glucose transporter. Brain Res. 1489 (2012), 113–120.
    • (2012) Brain Res. , vol.1489 , pp. 113-120
    • Yamazaki, Y.1    Harada, S.2    Tokuyama, S.3
  • 91
    • 84939245102 scopus 로고    scopus 로고
    • Relationship between cerebral sodium-glucose transporter and hyperglycemia in cerebral ischemia
    • Yamazaki, Y., Harada, S., Tokuyama, S., Relationship between cerebral sodium-glucose transporter and hyperglycemia in cerebral ischemia. Neurosci. Lett. 604 (2015), 134–139.
    • (2015) Neurosci. Lett. , vol.604 , pp. 134-139
    • Yamazaki, Y.1    Harada, S.2    Tokuyama, S.3
  • 92
    • 85011977766 scopus 로고    scopus 로고
    • Sodium influx through cerebral sodium-glucose transporter type 1 exacerbates the development of cerebral ischemic neuronal damage
    • Yamazaki, Y., Harada, S., Wada, T., Hagiwara, T., Yoshida, S., Tokuyama, S., Sodium influx through cerebral sodium-glucose transporter type 1 exacerbates the development of cerebral ischemic neuronal damage. Eur. J. Pharmacol. 799 (2017), 103–110.
    • (2017) Eur. J. Pharmacol. , vol.799 , pp. 103-110
    • Yamazaki, Y.1    Harada, S.2    Wada, T.3    Hagiwara, T.4    Yoshida, S.5    Tokuyama, S.6
  • 93
    • 84975229499 scopus 로고    scopus 로고
    • Sodium transport through the cerebral sodium-glucose transporter exacerbates neuron damage during cerebral ischaemia
    • Yamazaki, Y., Harada, S., Wada, T., Yoshida, S., Tokuyama, S., Sodium transport through the cerebral sodium-glucose transporter exacerbates neuron damage during cerebral ischaemia. J. Pharm. Pharmacol. 68 (2016), 922–931.
    • (2016) J. Pharm. Pharmacol. , vol.68 , pp. 922-931
    • Yamazaki, Y.1    Harada, S.2    Wada, T.3    Yoshida, S.4    Tokuyama, S.5
  • 94
    • 84944718007 scopus 로고    scopus 로고
    • Activation of cerebral sodium-glucose transporter type 1 function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemia
    • Yamazaki, Y., Ogihara, S., Harada, S., Tokuyama, S., Activation of cerebral sodium-glucose transporter type 1 function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemia. Neuroscience 310 (2015), 674–685.
    • (2015) Neuroscience , vol.310 , pp. 674-685
    • Yamazaki, Y.1    Ogihara, S.2    Harada, S.3    Tokuyama, S.4
  • 95
    • 84891952619 scopus 로고    scopus 로고
    • Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruption
    • Zehendner, C.M., Librizzi, L., Hedrich, J., Bauer, N.M., Angamo, E.A., de Curtis, M., Luhmann, H.J., Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruption. PLoS One, 8, 2013, e82823.
    • (2013) PLoS One , vol.8 , pp. e82823
    • Zehendner, C.M.1    Librizzi, L.2    Hedrich, J.3    Bauer, N.M.4    Angamo, E.A.5    de Curtis, M.6    Luhmann, H.J.7
  • 96
    • 70350550674 scopus 로고    scopus 로고
    • Dynamic expression of glucose transporters 1 and 3 in the brain of diabetic rats with cerebral ischemia reperfusion
    • Zhang, W., Zhang, L., Hou, W., Xu, Y., Xu, H., Lou, F., Zhang, Y., Wang, Q., Dynamic expression of glucose transporters 1 and 3 in the brain of diabetic rats with cerebral ischemia reperfusion. Chin. Med. J. (Engl.). 122 (2009), 1996–2001.
    • (2009) Chin. Med. J. (Engl.). , vol.122 , pp. 1996-2001
    • Zhang, W.1    Zhang, L.2    Hou, W.3    Xu, Y.4    Xu, H.5    Lou, F.6    Zhang, Y.7    Wang, Q.8
  • 97
    • 84962090275 scopus 로고    scopus 로고
    • Activation of the calcium-sensing receptor promotes apoptosis by modulating the JNK/p38 MAPK pathway in focal cerebral ischemia-reperfusion in mice
    • Zhen, Y., Ding, C., Sun, J., Wang, Y., Li, S., Dong, L., Activation of the calcium-sensing receptor promotes apoptosis by modulating the JNK/p38 MAPK pathway in focal cerebral ischemia-reperfusion in mice. Am. J. Transl. Res. 8 (2016), 911–921.
    • (2016) Am. J. Transl. Res. , vol.8 , pp. 911-921
    • Zhen, Y.1    Ding, C.2    Sun, J.3    Wang, Y.4    Li, S.5    Dong, L.6
  • 98
    • 84896355259 scopus 로고    scopus 로고
    • PDGF suppresses oxidative stress induced Ca2+ overload and calpain activation in neurons
    • Zheng, L.-S., Ishii, Y., Zhao, Q.-L., Kondo, T., Sasahara, M., PDGF suppresses oxidative stress induced Ca2+ overload and calpain activation in neurons. Oxid. Med. Cell. Longev., 2013, 2013, 367206.
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 367206
    • Zheng, L.-S.1    Ishii, Y.2    Zhao, Q.-L.3    Kondo, T.4    Sasahara, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.