Regulation of the human Na+-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 278, Issue 4 41-4, 2000, Pages

  Martín, Martín G ^a   Wang, Jiafang ^a   Solorzano Vargas, R Sergio ^a,b   Lam, Jason T ^a   Turk, Eric ^a   Wright, Ernest M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Glucose galactose malabsorption; Intestine; Sp2; Sp3; Transcription

Indexed keywords

NUCLEAR FACTOR I; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CELL STRAIN CACO 2; GENE ACTIVITY; GENE CONTROL; GENE ISOLATION; GENETIC TRANSCRIPTION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SODIUM TRANSPORT; TRANSACTIVATION;

EID: 0033996983     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.278.4.g591     Document Type: Article

References (48)

1. Bigger CB, Melnikova IN, and Gardner PD. Sp1 and Sp3 regulate expression of the neuronal nicotinic acetylcholine receptor B4 subunit gene. J Biol Chem 272: 25976-25982, 1997.
2. Courey AJ and Tjian R. Mechanisms of Transcriptional Control as Revealed by Studies of Human Transcription Factor Sp1. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1992, p. 743-769. (Transcriptional Regulation Monogr, 22)
3. Cuif M-H, Porteu A, Kahn A, and Vaulont S. Exploration of a liver-specific, glucose/insulin-responsive promoter in transgenic mice. J Biol Chem 268: 13769-13772, 1993.
4. Daniel S and Kim K. Sp1 mediates glucose activation of the acetyl-coA carboxylase promoter. J Biol Chem 271: 1385-1392, 1996.
5. Dukes ID, Sreenan S, Roe MW, Levisetti M, Zhou YP, Ostrega D, Bell GI, Pontoglio M, Yaniv M, Philipson L, and Polonsky KS. Defective pancreatic β-cell glycolytic signaling in hepatocyte nuclear factor-1α-deficient mice. J Biol Chem 273: 24457-24464, 1998.
6. Ernst P and Smale ST. Combinatorial regulation of transcription I: General aspects of transcriptional control. Immunity 2: 311-319, 1995.
7. Ferraris RP and Diamond J. Regulation of intestinal sugar transport. Physiol Rev 77: 257-302, 1997.
8. Hagen G, Dennig J, Preib A, Beato M, and Suske G. Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3. J Biol Chem 270: 24989-24994, 1995.
9. Hagen G, Muller S, Beato M, and Suske G. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res 20: 5519-5525, 1992.
10. Hagen G, Muller S, Beato M, and Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J 13: 3843-3851, 1994.
11. Hata Y, Duh E, Zhang K, Robinson GS, and Aiello LP. Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence. J Biol Chem 273: 19294-19303, 1998.
12. Hediger MA and Rhoads DB. Molecular physiology of sodium-glucose cotransporters. Physiol Rev 74: 993-1026, 1994.
13. Kwon HS, Kim MS, Edenberg HJ, and Hur MW. Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter. J Biol Chem 274: 20-28, 1999.
14. Lam JT, Martín MG, Turk E, Hirayama BA, Bosshard NU, Steinmann B, and Wright EM. Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects. Biochim Biophys Acta 1453: 297-303, 1999.
15. Lania L, Majello B, and De Luca P. Transcriptional regulation by the Sp family proteins. Int J Biochem Cell Biol. 29: 1313-1323, 1997.
16. Lescale-Matys L, Dyer J, Scott D, Freeman TC, Wright EM, and Shirazi-Beechey SP. Regulation of the ovine intestinal Na+/glucose co-transporter (SGLT1) is dissociated from mRNA abundance. Biochem J 291: 435-440, 1993.
17. Li TWH, Wang JF, Lam JT, Gutierrez EM, Solorzano-Vargus RS, Tsai HV, and Martín MG. Transcriptional control of the murine polymeric IgA receptor promoter by glucocorticoids. Am J Physiol Gastrointest Liver Physiol 276: G1425-G1434, 1999.
18. Mahraoui L, Rodolosse A, Barbat A, Dussaulx E, Zweibaum A, Rousset M, and Brot-Laroche E. Presence and differential expression of SGLT1, GLUT1, GLUT2, GLUT3 and GLUT5 hexose-transporter mRNAs in Caco-2 cell clones in relation to cell growth and glucose consumption. Biochem J 298: 629-633, 1994.
19. Markowitz AJ, Wu GD, Birkenmeier EH, and Traber PG. The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice. Am J Physiol Gastrointest Liver Physiol 265: G526-G539, 1993.
20. Martín MG, Turk E, Kerner C, and Wright EM. Compound missense mutations in sodium/D-glucose cotransporter (SGLT1) results in trafficking defects. Gastroenterology 112: 1206-1212.
21. + glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption. Nat Genet 12: 216-220, 1996.
22. Martín MG, Wang JF, Li TWH, Lam JT, Gutierrez EM, Solorzano-Vargas RS, and Tsai HV. Characterization of the 5′-flanking region of the murine polymeric IgA receptor gene. Am J Physiol Gastrointest Liver Physiol 275: G778-G788, 1998.
23. Mendel DB and Crabtree GR. HNF-1, a member of a novel class of dimerizing homeodomain proteins. J Biol Chem 266: 677-680, 1991.
24. Mendel DB, Hansen LP, Graves MK, Conley PB, and Crabtree GR. HNF-1α and HNF-1β (vHNF-1) share dimerization and homeo domains, but not activation domains, and form hererodimers in vitro. Genes Dev 5: 1042-1056, 1991.
25. Merika M and Orkin SH. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Kruppel family proteins Sp1 and EKLF. Mol Cell Biol 15: 2437-2447, 1995.
26. Mitchelmore C, Troelsen JT, Sjöström H, and Norén O. The HOXC11 homeodomain protein interacts with the lactasephlorizin hydrolase promoter and stimulates HNF1 α-dependent transcription. J Biol Chem 273: 13297-13306, 1998.
27. Nardelli J, Gibson TJ, Vesque C, and Charnay P. Base sequence discrimination by zinc-finger DNA-binding domains. Nature 349: 175-178, 1999.
28. Ogata H, Inoue N, and Podolsky DK. Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein. J Biol Chem 273: 3060-3067, 1998.
29. 1 cells - increased message stability after cyclic AMP elevation or differentiation inducer treatment. J Biol Chem 270: 20536-20542, 1995.
30. Pontoglio M, Barra J, Hadchouel M, Doyen A, Kress C, Bach JP, Babinet C, and Yaniv M. Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84: 575-585, 1996.
31. Pontoglio M, Faust DM, Doyen A, Yaniv M, and Weiss MC. Hepatocyte nuclear factor 1α gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase gene. Mol Cell Biol 17: 4948-4956, 1997.
32. Quandt K, Frech K, Karas H, Wingender E, and Werner T. MatInd and MatInspector - new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 23: 4878-4884, 1995.
33. +/glucose cotransporter 1 mRNA levels is transcriptionally regulated. J Biol Chem 273: 9510-9516, 1998.
34. Rodolosse A, Carriere V, Rousset M, and Lacasa M. Two HNF-1 binding sites govern the glucose repression of the human sucrase-isomaltase promoter. Biochem J 336: 115-123, 1998.
35. Rosmarin AG, Menglin L, Caprios DG, Shang J, and Simkevich CP. Sp1 cooperates with the ets transcription factor, GABP, to activate the CD18 (B2 leukocyte integrin) promoter. J Biol Chem 273: 13097-13103, 1998.
36. Rottman JN and Gordon JI. Comparison of the patterns of expression of rat intestinal fatty acid binding protein/human growth hormone fusion genes in cultured intestinal epithelial cell lines and in the gut epithelium of transgenic mice. J Biol Chem 268: 11994-12002, 1993.
37. Saffer JD, Jackson SP, and Annarella MB. Developmental expression of Sp1 in the mouse. Mol Cell Biol 11: 2189-2199, 1991.
38. Serfas MS and Tyner AL. HNF-1α and HNF-1β expression in mouse intestinal crypts. Am J Physiol Gastrointest Liver Physiol 265: G506-G513, 1993.
39. Talianidis I, Tambakaki A, Toursounova J, and Zannis VI. Complex interactions between SP1 bound to multiple distal regulatory sites and HNF-4 bound to the proximal promoter lead to transcriptional activation of liver-specific human APOCIII gene. Biochemistry 34: 10298-10309, 1995.
40. Traber PG and Silberg DG. Intestine-specific gene transcription. Annu Rev Physiol 58: 275-297, 1996.
41. +/glucose cotransporter gene SGLT1 to chromosome 22q13.1. Genomics 17: 752-754, 1993.
42. +/glucose cotransporter gene SGLT1. J Biol Chem 269: 15204-15209, 1994.
43. +/ glucose cotransporter. Nature 350: 354-356, 1991.
44. Von Strandmann EP, Nastos A, Holewa B, Senkel S, Weber H, and Ryffel GU. Patterning the expression of a tissue-specific transcription factor in embryogenesis: HNF1α gene activation during Xenopus development. Mech Dev 64: 7-17, 1997.
45. Wood IS, Allison GG, and Shirazi-Beechey SP. Isolation and characterization of a genomic region upstream from the ovine Na+/D-glucose cotransporter (SGLT1) cDNA. Biochem Biophys Res Commun 257: 533-537, 1999.
46. Wright EM, Hirayama BA, Loo DDF, Turk E, and Hager K. Intestinal sugar transport. In: Physiology of the Gastrointestinal Tract, edited by Johnson LR. New York, Raven: 1994, p. 1751-1772.
47. Yamagata K, Oda N, Kaisaki P, Menzel S, Furuta H, Vaxillaire M, Southam L, Cox RD, Lathrop GM, Borlraj VV, Chen X, Cox NJ, Oda Y, Yano H, Le Beau MM, Yamada S, Nishigori H, Takeda J, Fajans SS, Hattersley AT, Iwasaki N, Hansen T, Pedersen O, Polonsky KS and Bell GI. Mutations in the hepatoxyte nuclear factor-I alpha gene in maturity-onset diabetes of the young (MODY3). Nature 384: 455-458, 1996.
48. Zhang WQ, Shields JM, Sogawa K, Fujii-Kuriyama Y, and Yang VW. The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. J Biol Chem 273: 17917-17925, 1998.