MAP17 and SGLT1 Protein Expression Levels as Prognostic Markers for Cervical Tumor Patient Survival

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Perez, Marco ^a   Praena Fernandez, Juan M ^b   Felipe Abrio, Blanca ^a   Lopez Garcia, Maria A ^a   Lucena Cacace, Antonio ^a   Garcia, Angel ^c   Lleonart, Matilde ^c   Roncador, Guiovanna ^d   Marin, Juan J ^a,e   Carnero, Amancio ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^b Instituto de Biomedicina de Sevilla   (Spain)

^c Instituto de Recherca Val d'Hebron   (Spain)

^d Centro Nacional de Investigations Oncológicas   (Spain)

^e UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; GLUCOSE; MEMBRANE PROTEIN; PROTEIN MAP17; REACTIVE OXYGEN METABOLITE; SODIUM GLUCOSE COTRANSPORTER 1; UNCLASSIFIED DRUG;

ARTICLE; BRACHYTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; GENETIC TRANSCRIPTION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; MULTIPLE CYCLE TREATMENT; OXIDATIVE STRESS; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; TUMOR CELL LINE; UTERINE CERVIX TUMOR;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL SURVIVAL; CHEMORADIOTHERAPY; CISPLATIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MEMBRANE PROTEINS; MIDDLE AGED; PROGNOSIS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM-GLUCOSE TRANSPORTER 1; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 84873903994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056169     Document Type: Article

References (43)

1. Blasco T, Aramayona J, Alcalde A, Catalan J, Sarasa M, et al. (2003) Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes. Am J Physiol Renal Physiol 285: F799-810.
2. Jaeger C, Schaefer B, Wallich R, Kramer M, (2000) The membrane-associated protein pKe#192/MAP17 in human keratinocytes. J Invest Dermatol 2000 115: 375-380.
3. Pribanic S, Gisler S, Bacic D, Madjdpour C, Hernando N, et al. (2003) Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells. Am J Physiol Renal Physiol 285: F784-791.
4. Guijarro MV, Castro ME, Romero L, Moneo V, Carnero A, (2007) Large scale genetic screen identifies MAP17 as protein bypassing TNF-induced growth arrest. J Cell Biochem 101: 112-121.
5. Kocher O, Cheresh P, Lee SW, (1996) Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth. Am J Pathol 149: 493-500.
6. Guijarro MV, Leal JF, Fominaya J, Blanco-Aparicio C, Alonso S, et al. (2007) MAP17 overexpression is a common characteristic of carcinomas. Carcinogenesis 28: 1646-1652.
7. Guijarro MV, Vergel M, Marin JJ, Munoz-Galvan S, Ferrer I, et al. (2012) p38alpha limits the contribution of MAP17 to cancer progression in breast tumors. Oncogene.
8. Guijarro MV, Leal JF, Blanco-Aparicio C, Alonso S, Fominaya J, et al. (2007) MAP17 enhances the malignant behavior of tumor cells through ROS increase. Carcinogenesis 28: 2096-2104.
9. Guijarro MV, Link W, Rosado A, Leal JF, Carnero A, (2007) MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation. Carcinogenesis 28: 2443-2450.
10. Ganapathy V, Thangaraju M, Prasad PD, (2009) Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol Ther 121: 29-40.
11. Wright EM, Turk E, (2004) The sodium/glucose cotransport family SLC5. Pflugers Arch 447: 510-518.
12. Huang CY, Hsiao JK, Lu YZ, Lee TC, Yu LC, (2011) Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia. Lab Invest 91: 294-309.
13. Hanabata Y, Nakajima Y, Morita KI, Kayamori K, Omura K (2011) Coexpression of SGLT1 and EGFR is associated with tumor differentiation in oral squamous cell carcinoma. Odontology.
14. Haulica I, Boisteanu D, Neagu B, (2001) [The role of oxidative stress in normal and pathological adaptive reactions]. Rev Med Chir Soc Med Nat Iasi 105: 11-18.
15. Manda G, Nechifor MT, Neagu TM, (2009) Reactive Oxygen species, cancer and anticancer therapies. Curr Chem Biol 3: 342-366.
16. Behrend L, Henderson G, Zwacka RM, (2003) Reactive oxygen species in oncogenic transformation. Biochem Soc Trans 31: 1441-1444.
17. Burdon RH, Gill V, Rice-Evans C, (1990) Oxidative stress and tumour cell proliferation. Free Radic Res Commun 11: 65-76.
18. Kesic V, (2006) Management of cervical cancer. Eur J Surg Oncol 32: 832-837.
19. Rodriguez Villalba S, Diaz-Caneja Planell C, Cervera Grau JM, (2011) Current opinion in cervix carcinoma. Clin Transl Oncol 13: 378-384.
20. Lilic V, Lilic G, Filipovic S, Milosevic J, Tasic M, et al. (2009) Modern treatment of invasive carcinoma of the uterine cervix. J BUON 14: 587-592.
21. Guijarro MV, Leal JF, Fominaya J, Blanco-Aparicio C, Alonso S, et al. (2007) MAP17 overexpression is a common characteristic of carcinomas. Carcinogenesis.
22. Moneo V, Serelde BG, Leal JF, Blanco-Aparicio C, Diaz-Uriarte R, et al. (2007) Levels of p27(kip1) determine Aplidin sensitivity. Mol Cancer Ther 6: 1310-1316.
23. Moneo V, Serelde BG, Fominaya J, Leal JF, Blanco-Aparicio C, et al. (2007) Extreme sensitivity to Yondelis (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53. J Cell Biochem 100: 339-348.
24. Carnero A, Beach DH, (2004) Absence of p21WAF1 cooperates with c-myc in bypassing Ras-induced senescence and enhances oncogenic cooperation. Oncogene 23: 6006-6011.
25. Castro ME, Ferrer I, Cascon A, Guijarro MV, Lleonart M, et al. (2008) PPP1CA contributes to the senescence program induced by oncogenic Ras. Carcinogenesis 29: 491-499.
26. Blanco-Aparicio C, Pequeno B, Moneo V, Romero L, Leal JF, et al. (2005) Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria. Anticancer Drugs 16: 977-987.
27. Link W, Oyarzabal J, Serelde BG, Albarran MI, Rabal O, et al. (2009) Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases. J Biol Chem 284: 28392-28400.
28. Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, et al. (1997) Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275: 1649-1652.
29. Sundaresan M, Yu ZX, Ferrans VJ, Irani K, Finkel T, (1995) Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science 270: 296-299.
30. Burdon RH, (1996) Control of cell proliferation by reactive oxygen species. Biochem Soc Trans 24: 1028-1032.
31. Bae GU, Seo DW, Kwon HK, Lee HY, Hong S, et al. (1999) Hydrogen peroxide activates p70(S6k) signaling pathway. J Biol Chem 274: 32596-32602.
32. Klaunig JE, Xu Y, Isenberg JS, Bachowski S, Kolaja KL, et al. (1998) The role of oxidative stress in chemical carcinogenesis. Environ Health Perspect 106Suppl 1: 289-295.
33. Droge W, (2002) Free radicals in the physiological control of cell function. Physiol Rev 82: 47-95.
34. Storz P, (2005) Reactive oxygen species in tumor progression. Front Biosci 10: 1881-1896.
35. Marra M, Sordelli IM, Lombardi A, Lamberti M, Tarantino L, et al. (2011) Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview. J Transl Med 9: 171.
36. Finkel T, Holbrook NJ, (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247.
37. Fruehauf JP, Meyskens FL Jr, (2007) Reactive oxygen species: a breath of life or death? Clin Cancer Res 13: 789-794.
38. Simizu S, Takada M, Umezawa K, Imoto M, (1998) Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs. J Biol Chem 273: 26900-26907.
39. Simizu S, Umezawa K, Takada M, Arber N, Imoto M, (1998) Induction of hydrogen peroxide production and Bax expression by caspase-3(-like) proteases in tyrosine kinase inhibitor-induced apoptosis in human small cell lung carcinoma cells. Exp Cell Res 238: 197-203.
40. Yoshikawa T, Kokura S, Tainaka K, Naito Y, Kondo M, (1995) A novel cancer therapy based on oxygen radicals. Cancer Res 55: 1617-1620.
41. Nathan CF, Cohn ZA, (1981) Antitumor effects of hydrogen peroxide in vivo. J Exp Med 154: 1539-1553.
42. Benhar M, Engelberg D, Levitzki A, (2002) ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep 3: 420-425.
43. Nathan CF, Arrick BA, Murray HW, DeSantis NM, Cohn ZA, (1981) Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis. J Exp Med 153: 766-782.