Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type i interferon immune responses

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Choi, Hyun Jin ^a   Park, Areum ^a   Kang, Sujin ^a   Lee, Eunhye ^a   Lee, Taeyun A ^a   Ra, Eun A ^a   Lee, Jiseon ^b   Lee, Sungwook ^b   Park, Boyoun ^a  

^a Yonsei University   (South Korea)

^b National Cancer Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ALPHA ACTIN; ALPHA TUBULIN; BETA ACTIN; BETA INTERFERON; DIMER; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; INHIBITOR PROTEIN; INTERFERON REGULATORY FACTOR 3; LAMIN A; LAMIN C; MEMBRANE PROTEIN; MESSENGER RNA; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; MITOCHONDRIAL PROTEIN; MONOMER; MYC PROTEIN; PROTEIN KINASE; STIMULATOR OF INTERFERON GENE PROTEIN; TANK BINDING KINASE 1; TOM70 PROTEIN; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20; UNCLASSIFIED DRUG; US9 PROTEIN; VIRUS GLYCOPROTEIN; INTERFERON; IRF3 PROTEIN, HUMAN; MPYS PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; US9 PROTEIN, HUMAN HERPESVIRUS 5; VIRAL PROTEIN; VISA PROTEIN, HUMAN;

CELL; IMMUNE RESPONSE; INHIBITION; MITOCHONDRION; POLYMERIZATION; PROTEIN; VIRUS;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOPLASM; DELETION MUTANT; DIMERIZATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; FEMALE; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HEK293 CELL LINE; HEK293T CELL LINE; HELA CELL LINE; HFF-1 CELL LINE; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNE EVASION; IN VITRO STUDY; INNATE IMMUNITY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OLIGOMERIZATION; POLYMERIZATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VIRUS MUTANT; CELL CULTURE; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; U-937 CELL LINE; VIROLOGY;

HUMAN HERPESVIRUS 5;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; HEK293 CELLS; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE EVASION; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MITOCHONDRIA; SIGNAL TRANSDUCTION; U937 CELLS; VIRAL PROTEINS;

EID: 85040631711     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02624-8     Document Type: Article

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