GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS

Journal of Virology

Volumn 81, Issue 2, 2007, Pages 964-976

  Chen, Zihong ^a,b   Benureau, Yann ^c   Rijnbrand, Rene ^a,b,e   Yi, Jianzhong ^a,b   Wang, Ting ^a,b   Warter, Lucile ^c   Lanford, Robert E ^d   Weinman, Steven A ^a,b   Lemon, Stanley M ^a,b   Martin, Annette ^c   Li, Kui ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c INSTITUT PASTEUR   (France)

^d SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^e Immusol   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; NONSTRUCTURAL PROTEIN 3; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; HEPATITIS C; HEPATITIS GB VIRUS B; HOST RESISTANCE; HUMAN; HUMAN CELL; LIVER CELL; MITOCHONDRION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; RETINOIC ACID INDUCIBLE GENE 1; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; GB VIRUS B; GENE EXPRESSION REGULATION; HELA CELLS; HEPATOCYTES; HUMANS; INTERFERON REGULATORY FACTOR-3; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROTEIN SORTING SIGNALS; RECEPTORS, RETINOIC ACID; RNA HELICASES; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

ANIMALIA; HEPACIVIRUS; HEPATITIS C VIRUS; HEPATITIS GB VIRUS B; PRIMATES; RNA VIRUSES; SAGUINUS IMPERATOR;

EID: 33846106820     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02076-06     Document Type: Article

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