Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity

Journal of Hepatology

Volumn 59, Issue 1, 2013, Pages 52-58

  Ding, Qiang ^a   Cao, Xuezhi ^a   Lu, Jie ^a   Huang, Bing ^a   Liu, Yong Jun ^a,b   Kato, Nobuyuki ^c   Shu, Hong Bing ^d   Zhong, Jin ^a  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^c OKAYAMA UNIVERSITY   (Japan)

^d WUHAN UNIVERSITY   (China)

Author keywords

Interferon; Keywords Hepatitis C virus; NS4B; STING MITA; TBK 1

Indexed keywords

DOUBLE STRANDED RNA; NONSTRUCTURAL PROTEIN 4B;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HEPATITIS C VIRUS; IMMUNOPRECIPITATION; INNATE IMMUNITY; INTERFERON INDUCTION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RNA VIRUS;

CELL LINE; HEK293 CELLS; HEPACIVIRUS; HEPATITIS C, CHRONIC; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERONS; MEMBRANE PROTEINS; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84879173207     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.03.019     Document Type: Article

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