Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages

Redox Biology

Volumn 15, Issue , 2018, Pages 170-181

  Prattichizzo, Francesco ^a,b   De Nigris, Valeria ^b,c   Mancuso, Elettra ^b,d   Spiga, Rosangela ^b,d   Giuliani, Angelica ^e   Matacchione, Giulia ^e   Lazzarini, Raffaella ^e   Marcheselli, Fiorella ^f   Recchioni, Rina ^f   Testa, Roberto ^f   La Sala, Lucia ^a   Rippo, Maria Rita ^e   Procopio, Antonio Domenico ^e,f   Olivieri, Fabiola ^e,f   Ceriello, Antonio ^a,b,c  

^a IRCCS MULTIMEDICA   (Italy)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^e UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^f INRCA   (Italy)

Author keywords

Anion superoxide; Diabetes; Endothelial cells; Inflammation; Macrophages; Senescence associated secretory phenotype

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 8; MESSENGER RNA; PROTEIN P16; SOD1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SENESCENCE; SENESCENCE ASSOCIATED SECRETORY PHENOTYPE; THP-1 CELL LINE; U-937 CELL LINE; ANIMAL; CELL AGING; COMPLICATION; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; KIDNEY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; PHENOTYPE;

ANIMALS; CELLULAR SENESCENCE; DIABETES MELLITUS, TYPE 2; ENDOTHELIAL CELLS; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; HYPERGLYCEMIA; INFLAMMATION; KIDNEY; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MICE; PHENOTYPE; SUPEROXIDE DISMUTASE-1;

EID: 85038024525     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2017.12.001     Document Type: Article

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