Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

Cancer Cell

Volumn 32, Issue 6, 2017, Pages 869-883.e5

  Canli, Özge ^a   Nicolas, Adele M ^a   Gupta, Jalaj ^a   Finkelmeier, Fabian ^a,b   Goncharova, Olga ^a   Pesic, Marina ^a   Neumann, Tobias ^a   Horst, David ^c,d   Löwer, Martin ^e   Sahin, Ugur ^d,e   Greten, Florian R ^a,d  

^a INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

cancer initiation; chronic inflammation; GPx4; myeloid cells; oxidative stress

Indexed keywords

HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; EPITHELIUM; INTESTINE EPITHELIUM CELL; MOLECULAR INTERACTION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; DRUG EFFECTS; EPITHELIUM CELL; METABOLISM; MUTANT MOUSE STRAIN; MUTATION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; DNA DAMAGE; EPITHELIAL CELLS; HYDROGEN PEROXIDE; MICE; MICE, MUTANT STRAINS; MUTAGENESIS; MUTATION; MYELOID CELLS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85037031016     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2017.11.004     Document Type: Article

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