Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression

Redox Biology

Volumn 15, Issue , 2018, Pages 86-96

  Bellanti, Francesco ^a   Villani, Rosanna ^a   Tamborra, Rosanna ^a   Blonda, Maria ^a   Iannelli, Giuseppina ^a   di Bello, Giorgia ^a   Facciorusso, Antonio ^a   Poli, Giuseppe ^b   Iuliano, Luigi ^c   Avolio, Carlo ^a   Vendemiale, Gianluigi ^a   Serviddio, Gaetano ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cholesterol excess; Fatty acids; Mitochondria; Non alcoholic fatty liver disease; Oxysterols

Indexed keywords

5ALPHA CHOLESTANE 3BETA,5,6BETA TRIOL; FATTY ACID DERIVATIVE; OXYSTEROL; STEROL; UNCLASSIFIED DRUG; FATTY ACID; REACTIVE OXYGEN METABOLITE;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHOLESTEROL DIET; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; ENERGY BALANCE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; ISOLATED LIVER; LIPID DIET; LIPID STORAGE; LIVER CELL; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; TRANSCRIPTION REGULATION; DISEASE EXACERBATION; GENETICS; LIPID METABOLISM; LIVER; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY;

APOPTOSIS; DIET, HIGH-FAT; DISEASE PROGRESSION; FATTY ACIDS; HEPATOCYTES; HUMANS; LIPID METABOLISM; LIVER; MITOCHONDRIA, LIVER; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYSTEROLS; REACTIVE OXYGEN SPECIES;

EID: 85036638731     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2017.11.016     Document Type: Article

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