The influence of an obesogenic diet on oxysterol metabolism in C57BL/6J mice

Cholesterol

Volumn 2014, Issue , 2014, Pages

  Wooten, Joshua S ^a,b   Wu, Huaizhu ^a   Raya, Joe ^a   Perrard, Xiaoyuan Dai ^a   Gaubatz, John ^a   Hoogeveen, Ron C ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

26 HYDROXYCHOLESTEROL; 4 BETA HYDROXYCHOLESTEROL; 4 BETA HYDROXYLASE; 5,6 ALPHA EPOXYCHOLESTEROL; 5,6 BETA EPOXYCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL DERIVATIVE; CYTOCHROME P450; HIGH DENSITY LIPOPROTEIN; ISOENZYME; LOW DENSITY LIPOPROTEIN; OXYGENASE; OXYSTEROL; PHOSPHOLIPID; SULFOTRANSFERASE; SULT2B1B ISOENZYME; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL DIET; CONTROLLED STUDY; DETOXIFICATION; DIETARY INTAKE; DISEASE SEVERITY; DYSLIPIDEMIA; ENZYME METABOLISM; ENZYME SYNTHESIS; LIPID COMPOSITION; LIPID DIET; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION;

EID: 84894797629     PISSN: 20901283     EISSN: 20901291     Source Type: Journal    
DOI: 10.1155/2014/843468     Document Type: Article

References (54)

1. Cusi K., The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes. Current Diabetes Reports 2010 10 4 306 315 2-s2.0-77956395533 10.1007/s11892-010-0122-6
2. Neuschwander-Tetri B. A., Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology 2010 52 2 774 788 2-s2.0-77955690182 10.1002/hep.23719
3. Goldstein J. L., Brown M. S., Regulation of the mevalonate pathway. Nature 1990 343 6257 425 430 2-s2.0-0025120211 10.1038/343425a0
4. Brown A. J., Jessup W., Oxysterols and atherosclerosis. Atherosclerosis 1999 142 1 1 28 2-s2.0-0032890337 10.1016/S0021-9150(98)00196-8
5. Poli G., Sottero B., Gargiulo S., Leonarduzzi G., Cholesterol oxidation products in the vascular remodeling due to atherosclerosis. Molecular Aspects of Medicine 2009 30 3 180 189 2-s2.0-67349248123 10.1016/j.mam.2009.02.003
6. Matsui H., Okumura K., Mukawa H., Hibino M., Toki Y., Ito T., Increased oxysterol contents in diabetic rat hearts: their involvement in diabetic cardiomyopathy. Canadian Journal of Cardiology 1997 13 4 373 379 2-s2.0-0030902933
7. Yoshioka N., Adachi J., Ueno Y., Yoshida K.-I., Oxysterols increase in diabetic rats. Free Radical Research 2005 39 3 299 304 2-s2.0-15944395537 10.1080/10715760400023002
8. Whaley-Connell A., McCullough P. A., Sowers J. R., The role of oxidative stress in the metabolic syndrome. Reviews in Cardiovascular Medicine 2011 12 1 21 29 2-s2.0-79957717018 10.3909/ricm0555
9. Schumaker V. N., Puppione D. L., Sequential flotation ultracentrifugation. Methods in Enzymology 1986 128 155 170 2-s2.0-0022556074
10. Rodríguez-Sureda V., Peinado-Onsurbe J., A procedure for measuring triacylglyceride and cholesterol content using a small amount of tissue. Analytical Biochemistry 2005 343 2 277 282 2-s2.0-23044490171 10.1016/j.ab.2005.05.009
11. Brown M. S., Ho Y. K., Goldstein J. L., The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters. The Journal of Biological Chemistry 1980 255 19 9344 9352 2-s2.0-0019162068
12. Dzeletovic S., Breuer O., Lund E., Diczfalusy U., Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry. Analytical Biochemistry 1995 225 1 73 80 2-s2.0-0028816863 10.1006/abio.1995.1110
13. FOLCH J., LEES M., Sloane Stanley G. H., A simple method for the isolation and purification of total lipides from animal tissues. The Journal of Biological chemistry 1957 226 1 497 509 2-s2.0-70449158340
14. Wu H., Ghosh S., Perrard X. D., Feng L., Garcia G. E., Perrard J. L., Sweeney J. F., Peterson L. E., Chan L., Smith C. W., Ballantyne C. M., T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation 2007 115 8 1029 1038 2-s2.0-33847280286 10.1161/CIRCULATIONAHA.106.638379
15. Nishina P. M., Lowe S., Wang J., Paigen B., Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 1994 43 5 549 553 2-s2.0-0028281559 10.1016/0026-0495(94)90194-5
16. Silver D. L., Wang N., Tall A. R., Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake. Journal of Clinical Investigation 2000 105 2 151 159 2-s2.0-0033972321
17. Nishina P. M., Naggert J. K., Verstuyft J., Paigen B., Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 1994 43 5 554 558 2-s2.0-0028220011 10.1016/0026-0495(94) 90195-3
18. Silver D. L., Jiang X.-C., Tall A. R., Increased high density lipoprotein (HDL), defective hepatic catabolism of apoA-I and apoA-II, and decreased apoA-I mRNA in ob/ob mice: possible role of leptin in stimulation of HDL turnover. The Journal of Biological Chemistry 1999 274 7 4140 4146 2-s2.0-0033548092 10.1074/jbc.274.7.4140
19. Gruen M. L., Plummer M. R., Zhang W., Posey K. A., Linton M. F., Fazio S., Hasty A. H., Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I. Journal of Lipid Research 2005 46 9 2007 2014 2-s2.0-24344483109 10.1194/jlr.M500181-JLR200
20. Rigotti A., Trigatti B. L., Penman M., Rayburn H., Herz J., Krieger M., A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proceedings of the National Academy of Sciences of the United States of America 1997 94 23 12610 12615 2-s2.0-0030729724 10.1073/pnas.94.23.12610
21. Plummer M. R., Hasty A. H., Atherosclerotic lesion formation and triglyceride storage in obese apolipoprotein AI-deficient mice. Journal of Nutritional Biochemistry 2008 19 10 664 673 2-s2.0-50949117507 10.1016/j.jnutbio.2007.08.009
22. LeBoeuf R. C., Tsao W. W., Kirk E., Childs M. T., Cholesterol feeding induces cholesterol-rich VLDL in atherosclerosis- susceptible mice regardless of dietary fat content. Nutrition Research 1993 13 5 549 561 2-s2.0-0027153272
23. Christ E. R., Carroll P. V., Albany E., Umpleby A. M., Lumb P. J., Wierzbicki A. S., Simpson H. L., Sönksen P. H., Russell-Jones D. L., Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus. Clinical Endocrinology 2001 55 6 777 787 2-s2.0-0035652667 10.1046/j.1365-2265.2001.01407.x
24. Fazio S., Linton M. F., Mouse models of hyperlipidemia and atherosclerosis. Front Biosci 2001 6 D515 525 2-s2.0-0035287440
25. LeBoeuf R. C., Puppione D. L., Schumaker V. N., Lusis A. J., Genetic control of lipid transport in mice. I. Structural properties and polymorphisms of plasma lipoproteins. The Journal of Biological Chemistry 1983 258 8 5063 5070 2-s2.0-0020604267
26. Kennedy A. J., Ellacott K. L. J., King V. L., Hasty A. H., Mouse models of the metabolic syndrome. Disease Models and Mechanisms 2010 3 3-4 156 166 2-s2.0-77949474691 10.1242/dmm.003467
27. Breuer O., Identification and quantitation of cholest-5-ene-3 β4 β -diol in rat liver and human plasma. Journal of Lipid Research 1995 36 11 2275 2281 2-s2.0-0028971227
28. Bodin K., Bretillon L., Aden Y., Bertilsson L., Broomé U., Einarsson C., Diczfalusy U., Antiepileptic drugs increase plasma levels of 4 β -hydroxycholesterol in humans. Evidence for involvement of cytochrome P450 3A4. The Journal of Biological Chemistry 2001 276 42 38685 38689 2-s2.0-0035914368 10.1074/jbc.M105127200
29. Goodwin B., Gauthier K. C., Umetani M., Watson M. A., Lochansky M. I., Collins J. L., Leitersdorf E., Mangelsdorf D. J., Kliewer S. A., Repa J. J., Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Proceedings of the National Academy of Sciences of the United States of America 2003 100 1 223 228 2-s2.0-0037422578 10.1073/pnas.0237082100
30. Staudinger J. L., Goodwin B., Jones S. A., Hawkins-Brown D., MacKenzie K. I., LaTour A., Liu Y., Klaassen C. D., Brown K. K., Reinhard J., Willson T. M., Koller B. H., Kliewer S. A., The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proceedings of the National Academy of Sciences of the United States of America 2001 98 6 3369 3374 2-s2.0-0035853165 10.1073/pnas.051551698
31. Gnerre C., Schuster G. U., Roth A., Handschin C., Johansson L., Looser R., Parini P., Podvinec M., Robertsson K., Gustafsson J.-Å., Meyer U. A., LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver. Journal of Lipid Research 2005 46 8 1633 1642 2-s2.0-23244432637 10.1194/jlr.M400453-JLR200
32. Björkhem I., Lütjohann D., Diczfalusy U., Ståhle L., Ahlborg G., Wahren J., Cholesterol homeostasis in human brain: turnover of 24S- hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. Journal of Lipid Research 1998 39 8 1594 1600 2-s2.0-0031848338
33. Meaney S., Hassan M., Sakinis A., Lütjohann D., Von Bergmann K., Wennmalm Å., Diczfalusy U., Björkhem I., Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study. Journal of Lipid Research 2001 42 1 70 78 2-s2.0-0035133061
34. Bodin K., Andersson U., Rystedt E., Ellis E., Norlin M., Pikuleva I., Eggertsen G., Björkhem I., Diczfalusy U., Metabolism of 4 β -hydroxycholesterol in humans. The Journal of Biological Chemistry 2002 277 35 31534 31540 2-s2.0-0037200017 10.1074/jbc.M201712200
35. Mito N., Hosoda T., Kato C., Sato K., Change of cytokine balance in diet-induced obese mice. Metabolism 2000 49 10 1295 1300 2-s2.0-0033788555 10.1053/meta.2000.9523
36. Pacifico L., Di Renzo L., Anania C., Osborn J. F., Ippoliti F., Schiavo E., Chiesa C., Increased T-helper interferon- γ -secreting cells in obese children. European Journal of Endocrinology 2006 154 5 691 697 2-s2.0-33744526526 10.1530/eje.1.02138
37. Rocha V. Z., Folco E. J., Sukhova G., Shimizu K., Gotsman I., Vernon A. H., Libby P., Interferon- γ a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity. Circulation Research 2008 103 5 467 476 2-s2.0-54049086276 10.1161/CIRCRESAHA.108.177105
38. Park K., Scott A. L., Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons. Journal of Leukocyte Biology 2010 88 6 1081 1087 2-s2.0-78649752711 10.1189/jlb.0610318
39. Wu H., Perrard X. D., Wang Q., Perrard J. L., Polsani V. R., Jones P. H., Smith C. W., Ballantyne C. M., CD11c expression in adipose tissue and blood and its role in diet-induced obesity. Arteriosclerosis, Thrombosis, and Vascular Biology 2010 30 2 186 192 2-s2.0-75149197353 10.1161/ATVBAHA.109.198044
40. Westman J., Kallin B., Björkhem I., Nilsson J., Diczfalusy U., Sterol 27-hydroxylase- and apoAI/phospholipid-mediated efflux of cholesterol from cholesterol-laden macrophages: evidence for an inverse relation between the two mechanisms. Arteriosclerosis, Thrombosis, and Vascular Biology 1998 18 4 554 561 2-s2.0-0031955904
41. Hirayama T., Mizokami Y., Honda A., Homma Y., Ikegami T., Saito Y., Miyazaki T., Matsuzaki Y., Serum concentration of 27-hydroxycholesterol predicts the effects of high-cholesterol diet on plasma LDL cholesterol level. Hepatology Research 2009 39 2 149 156 2-s2.0-59149088091 10.1111/j.1872-034X. 2008.00450.x
42. Lyons M. A., Samman S., Gatto L., Brown A. J., Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols. Journal of Lipid Research 1999 40 10 1846 1857 2-s2.0-0032832986
43. Schweizer R. A. S., Zürcher M., Balazs Z., Dick B., Odermatt A., Rapid hepatic metabolism of 7-ketocholesterol by 11 β -hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme. The Journal of Biological Chemistry 2004 279 18 18415 18424 2-s2.0-2442513350 10.1074/jbc.M313615200
44. Brown A. J., Watts G. F., Burnett J. R., Dean R. T., Jessup W., Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture. The Journal of Biological Chemistry 2000 275 36 27627 27633 2-s2.0-0034623160 10.1074/jbc.M004060200
45. Li T., Matozel M., Boehme S., Kong B., Nilsson L.-M., Guo G., Ellis E., Chiang J. Y. L., Overexpression of cholesterol 7 α -hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis. Hepatology 2011 53 3 996 1006 2-s2.0-79952218554 10.1002/hep.24107
46. Li T., Owsley E., Matozel M., Hsu P., Novak C. M., Chiang J. Y. L., Transgenic expression of cholesterol 7 α -hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice. Hepatology 2010 52 2 678 690 2-s2.0-77955667250 10.1002/hep.23721
47. Roberts C. K., Liang K., Barnard R. J., Kim C. H., Vaziri N. D., HMG-CoA reductase, cholesterol 7 α -hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X. Kidney International 2004 66 4 1503 1511 2-s2.0-4644311898 10.1111/j.1523-1755.2004.00914.x
48. Bjorkhem I., Breuer O., Angelin B., Wikstrom S.-A., Assay of unesterified cholesterol-5,6-epoxide in human serum by isotope dilution mass spectrometry. Levels in the healthy state and in hyperlipoproteinemia. Journal of Lipid Research 1988 29 8 1031 1038 2-s2.0-0023778240
49. Smith L. L., Johnson B. H., Biological activities of oxysterols. Free Radical Biology and Medicine 1989 7 3 285 332 2-s2.0-0024430192
50. Berrodin T. J., Shen Q., Quinet E. M., Yudt M. R., Freedman L. P., Nagpal S., Identification of 5 α6 α -epoxycholesterol as a novel modulator of liver X receptor activity. Molecular Pharmacology 2010 78 6 1046 1058 2-s2.0-78649944880 10.1124/mol.110.065193
51. Joseph S. B., Castrillo A., Laffitte B. A., Mangelsdorf D. J., Tontonoz P., Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nature Medicine 2003 9 2 213 219 2-s2.0-0037324340 10.1038/nm820
52. Zelcer N., Tontonoz P., Liver X receptors as integrators of metabolic and inflammatory signaling. Journal of Clinical Investigation 2006 116 3 607 614 2-s2.0-33644651160 10.1172/JCI27883
53. Fuda H., Javitt N. B., Mitamura K., Ikegawa S., Strott C. A., Oxysterols are substrates for cholesterol sulfotransferase. Journal of Lipid Research 2007 48 6 1343 1352 2-s2.0-34548150762 10.1194/jlr.M700018-JLR200
54. Javitt N. B., Lee Y. C., Shimizu C., Fuda H., Strott C. A., Cholesterol and hydroxycholesterol sulfotransferases: identification, distinction from dehydroepiandrosterone sulfotransferase, and differential tissue expression. Endocrinology 2001 142 7 2978 2984 2-s2.0-0034991507 10.1210/en.142.7.2978