Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

Journal of Hepatology

Volumn 60, Issue 4, 2014, Pages 816-823

  Franko, Andras ^a,b,c   Von Kleist Retzow, Jürgen Christoph ^a   Neschen, Susanne ^b,c   Wu, Moya ^b,c   Schommers, Philipp ^a   Böse, Marlen ^a   Kunze, Alexander ^a   Hartmann, Ursula ^a   Sanchez Lasheras, Carmen ^a   Stoehr, Oliver ^a   Huntgeburth, Michael ^a   Brodesser, Susanne ^a,d   Irmler, Martin ^b   Beckers, Johannes ^b,c,e   De Angelis, Martin Hrabé ^b,c,e   Paulsson, Mats ^a,d   Schubert, Markus ^a,d,f   Wiesner, Rudolf J ^a,d,f  

^a UNIVERSITY OF COLOGNE   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f SCIVIAS Hospital St Josef   (Germany)

Author keywords

Insulin receptor; Liver metabolism; Mitochondrial biogenesis; Mitochondrial gene expression; Type 2 diabetes mellitus

Indexed keywords

CARDIOLIPIN; CHOLESTEROL; DIACYLGLYCEROL; FATTY ACID; GLUCOSE; INSULIN; OXYGEN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; STREPTOZOCIN; TRIACYLGLYCEROL; ADENINE NUCLEOTIDE TRANSLOCASE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; ION CHANNEL; IRS1 PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIABETES MELLITUS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FATTY LIVER; GENE EXPRESSION; GENETIC DISORDER; GENETIC MANIPULATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPOINSULINEMIA; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LIPID DIET; LIPID LIVER LEVEL; LIVER MITOCHONDRION; MICROARRAY ANALYSIS; MOUSE; MOUSE MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTON MOTIVE FORCE; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; THIN LAYER CHROMATOGRAPHY; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; DEFICIENCY; DIABETES MELLITUS, TYPE 2; EXPERIMENTAL DIABETES MELLITUS; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; OXIDATIVE PHOSPHORYLATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; FATTY LIVER; GENE EXPRESSION; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; ION CHANNELS; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, LIVER; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL PROTEINS; OBESITY; OXIDATIVE PHOSPHORYLATION; PROTON-MOTIVE FORCE; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 84896405837     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.11.020     Document Type: Article

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