Heterologous Gene Expression of N-Terminally Truncated Variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular Polyketide Synthase

ACS Chemical Biology

Volumn 12, Issue 11, 2017, Pages 2725-2729

  Yuzawa, Satoshi ^a,b,h   Bailey, Constance B ^a   Fujii, Tatsuya ^g   Jocic, Renee ^a,h   Barajas, Jesus F ^h   Benites, Veronica T ^a,b,h   Baidoo, Edward E K ^a,b,h   Chen, Yan ^a,b   Petzold, Christopher J ^a,b,h   Katz, Leonard ^c   Keasling, Jay D ^a,b,c,d,e,f  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b JOINT BIOENERGY INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d University of California at Berkeley   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Chalmers University of Technology   (Denmark)

^g NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^h Agile BioFoundary   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; LIPPKS1 PROTEIN; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CODON; CONTROLLED STUDY; GENE EXPRESSION; GENETIC VARIABILITY; HOST; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; STREPTOMYCES VENEZUELAE; STRUCTURAL MODEL; AMINO ACID SEQUENCE; BACTERIAL GENE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETIC ENGINEERING; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; STREPTOMYCES;

AMINO ACID SEQUENCE; GENE EXPRESSION; GENES, BACTERIAL; GENETIC ENGINEERING; MODELS, MOLECULAR; POLYKETIDE SYNTHASES; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 85034642032     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.7b00714     Document Type: Article

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