Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases

Biochemistry

Volumn 51, Issue 18, 2012, Pages 3708-3710

  Yuzawa, Satoshi ^a   Kapur, Shiven ^a   Cane, David E ^c   Khosla, Chaitan ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6-DEOXYERYTHRONOLIDE B SYNTHASE; ACYL CARRIER PROTEINS; ALANINE-SCANNING MUTAGENESIS; ARGININE RESIDUE; ASSEMBLY LINE; CHAIN ELONGATION; CONSERVED RESIDUES; INTER-DOMAIN; KETOSYNTHASE; LIMITED PROTEOLYSIS; MULTI-MODULAR; POLYKETIDE BIOSYNTHESIS; POLYKETIDE SYNTHASES;

AMINO ACIDS; BIOCHEMISTRY; KETONES;

PLANTS (BOTANY);

6 DEOXYERYTHRONOLIDE B SYNTHASE; ACYLTRANSFERASE; ALANINE; ARGININE; DODECYL SULFATE SODIUM; KETOSYNTHASE; POLYKETIDE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME STRUCTURE; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

ACYL CARRIER PROTEIN; ACYLTRANSFERASES; ARGININE; ERYTHROMYCIN; MODELS, MOLECULAR; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; SACCHAROPOLYSPORA;

EID: 84860748631     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300399u     Document Type: Article

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