Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, i and J

Journal of Antibiotics

Volumn 67, Issue 1, 2014, Pages 127-132

  Rateb, Mostafa E ^a   Yu, Zhiguo ^a   Yan, Yijun ^a,b   Yang, Dong ^a   Huang, Tingting ^a   Vodanovic Jankovic, Sanja ^c   Kron, Michael A ^c   Shen, Ben ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

AsnRS inhibitor; Filariasis; Medium optimization; S. sp 17944; Tirandamycin

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIFILARIAL AGENT; APRAMYCIN; BACTERIAL RNA; CHLORAMPHENICOL; ERYTHROMYCIN; GENTAMICIN; KANAMYCIN; NALIDIXIC ACID; NEOMYCIN; SPECTINOMYCIN; THIOSTREPTON; TIRANDAMYCIN B; TIRANDAMYCIN H; TIRANDAMYCIN I; TIRANDAMYCIN J; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM CONJUGATION; BIOSYNTHESIS; BRUGIAN FILARIASIS; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; DRUG STRUCTURE; FERMENTATION OPTIMIZATION; GENETIC MANIPULATION; HETERONUCLEAR MULTIPLE BOND CORRELATION; MOLECULAR CLONING; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

AMINOGLYCOSIDES; CULTURE MEDIA; DRUG DESIGN; FERMENTATION; FILARICIDES; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84893112499     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.50     Document Type: Article

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