-
1
-
-
38049044476
-
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
-
Fattovich G, Bortolotti F, Donato F. Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors. J Hepatol 2008;48:335-352.
-
(2008)
J Hepatol
, vol.48
, pp. 335-352
-
-
Fattovich, G.1
Bortolotti, F.2
Donato, F.3
-
2
-
-
84947346338
-
Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013
-
Schweitzer A, Horn J, Mikolajczyk RT, Krause G, Ott JJ. Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013. Lancet 2015;386:1546-1555.
-
(2015)
Lancet
, vol.386
, pp. 1546-1555
-
-
Schweitzer, A.1
Horn, J.2
Mikolajczyk, R.T.3
Krause, G.4
Ott, J.J.5
-
3
-
-
84874638128
-
Chronic hepatitis B: What should be the goal for new therapies?
-
Block TM, Gish R, Guo H, Mehta A, Cuconati A, Thomas London W, Guo JT. Chronic hepatitis B: What should be the goal for new therapies? Antiviral Res 2013;98:27-34.
-
(2013)
Antiviral Res
, vol.98
, pp. 27-34
-
-
Block, T.M.1
Gish, R.2
Guo, H.3
Mehta, A.4
Cuconati, A.5
Thomas London, W.6
Guo, J.T.7
-
4
-
-
84955183087
-
Present and future therapies of hepatitis B: From discovery to cure
-
Liang TJ, Block TM, McMahon BJ, Ghany MG, Urban S, Guo J, et al. Present and future therapies of hepatitis B: From discovery to cure. Hepatology 2015;62:1893-1908.
-
(2015)
Hepatology
, vol.62
, pp. 1893-1908
-
-
Liang, T.J.1
Block, T.M.2
McMahon, B.J.3
Ghany, M.G.4
Urban, S.5
Guo, J.6
-
5
-
-
84960910158
-
New therapies for chronic hepatitis B
-
Bitton Alaluf M, Shlomai A. New therapies for chronic hepatitis B. Liver Int 2016;36:775-782.
-
(2016)
Liver Int
, vol.36
, pp. 775-782
-
-
Bitton Alaluf, M.1
Shlomai, A.2
-
6
-
-
20444505037
-
Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy
-
Sung JJY, Wong ML, Bowden S, Liew CT, Hui AY, Wong VW, et al. Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 2005;128:1890-1897.
-
(2005)
Gastroenterology
, vol.128
, pp. 1890-1897
-
-
Sung, J.J.Y.1
Wong, M.L.2
Bowden, S.3
Liew, C.T.4
Hui, A.Y.5
Wong, V.W.6
-
7
-
-
2942532722
-
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
-
Werle–Lapostolle B, Bowden S, Locarnini S, Wursthorn K, Petersen J, Lau G, et al. Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 2004;126:1750-1758.
-
(2004)
Gastroenterology
, vol.126
, pp. 1750-1758
-
-
Werle–Lapostolle, B.1
Bowden, S.2
Locarnini, S.3
Wursthorn, K.4
Petersen, J.5
Lau, G.6
-
8
-
-
85015289156
-
The cancer epigenome: concepts, challenges, and therapeutic opportunities
-
Dawson MA. The cancer epigenome: concepts, challenges, and therapeutic opportunities. Science 2017;355:1147-1152.
-
(2017)
Science
, vol.355
, pp. 1147-1152
-
-
Dawson, M.A.1
-
9
-
-
0028095561
-
Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell
-
Bock CT, Schranz P, Schröder CH, Zentgraf H. Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell. Virus Genes 1994;8:215-229.
-
(1994)
Virus Genes
, vol.8
, pp. 215-229
-
-
Bock, C.T.1
Schranz, P.2
Schröder, C.H.3
Zentgraf, H.4
-
10
-
-
0035896013
-
Structural organization of the hepatitis B virus minichromosome
-
Bock CT, Schwinn S, Locarnini S, Fyfe J, Manns MP, Trautwein C, et al. Structural organization of the hepatitis B virus minichromosome. J Mol Biol 2001;307:183-196.
-
(2001)
J Mol Biol
, vol.307
, pp. 183-196
-
-
Bock, C.T.1
Schwinn, S.2
Locarnini, S.3
Fyfe, J.4
Manns, M.P.5
Trautwein, C.6
-
11
-
-
19944432566
-
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia
-
Byrd JC. A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia. Blood 2004;105:959-967.
-
(2004)
Blood
, vol.105
, pp. 959-967
-
-
Byrd, J.C.1
-
12
-
-
84879327902
-
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
-
Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, et al. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. eLife 2012;1:e00049.
-
(2012)
eLife
, vol.1
-
-
Yan, H.1
Zhong, G.2
Xu, G.3
He, W.4
Jing, Z.5
Gao, Z.6
-
13
-
-
84866160398
-
Entry of hepatitis B virus into immortalized human primary hepatocytes by clathrin-dependent endocytosis
-
Huang HC, Chen CC, Chang WC, Tao MH, Huang C. Entry of hepatitis B virus into immortalized human primary hepatocytes by clathrin-dependent endocytosis. J Virol 2012;86:9443-9453.
-
(2012)
J Virol
, vol.86
, pp. 9443-9453
-
-
Huang, H.C.1
Chen, C.C.2
Chang, W.C.3
Tao, M.H.4
Huang, C.5
-
14
-
-
84939956694
-
Molecular biology of hepatitis B virus infection
-
Seeger C, Mason WS. Molecular biology of hepatitis B virus infection. Virology 2015;479:672-686.
-
(2015)
Virology
, vol.479
, pp. 672-686
-
-
Seeger, C.1
Mason, W.S.2
-
15
-
-
84866159827
-
Characterization of nucleosome positioning in hepadnaviral covalently closed circular DNA minichromosomes
-
Shi L, Li S, Shen F, Li H, Qian S, Lee DH, et al. Characterization of nucleosome positioning in hepadnaviral covalently closed circular DNA minichromosomes. J Virol 2012;86:10059-10069.
-
(2012)
J Virol
, vol.86
, pp. 10059-10069
-
-
Shi, L.1
Li, S.2
Shen, F.3
Li, H.4
Qian, S.5
Lee, D.H.6
-
16
-
-
0034749753
-
Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis
-
Zhu Y, Yamamoto T, Cullen J, Saputelli J, Aldrich CE, Miller DS, et al. Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J Virol 2001;75:311-322.
-
(2001)
J Virol
, vol.75
, pp. 311-322
-
-
Zhu, Y.1
Yamamoto, T.2
Cullen, J.3
Saputelli, J.4
Aldrich, C.E.5
Miller, D.S.6
-
18
-
-
0033965482
-
Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections
-
Guo JT, Zhou H, Liu C, Aldrich C, Saputelli J, Whitaker T, et al. Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections. J Virol 2000;74:1495-1505.
-
(2000)
J Virol
, vol.74
, pp. 1495-1505
-
-
Guo, J.T.1
Zhou, H.2
Liu, C.3
Aldrich, C.4
Saputelli, J.5
Whitaker, T.6
-
19
-
-
85042868989
-
Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
-
Apr 20., [Epub ahead of print]
-
Allweiss L, Volz T, Giersch K, Kah J, Raffa G, Petersen J, et al. Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo. Gut 2017 Apr 20. pii: gutjnl-2016-312162. doi: 10.1136/gutjnl-2016-312162. [Epub ahead of print]
-
(2017)
Gut
-
-
Allweiss, L.1
Volz, T.2
Giersch, K.3
Kah, J.4
Raffa, G.5
Petersen, J.6
-
20
-
-
77954226664
-
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
-
Lutgehetmann M, Volz T, Köpke A, Broja T, Tigges E, Lohse AW, et al. In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice. Hepatology 2010;52:16-24.
-
(2010)
Hepatology
, vol.52
, pp. 16-24
-
-
Lutgehetmann, M.1
Volz, T.2
Köpke, A.3
Broja, T.4
Tigges, E.5
Lohse, A.W.6
-
22
-
-
2542516261
-
HBsAg seroclearance in chronic hepatitis B in the Chinese: virological, histological, and clinical aspects
-
Yuen MF, Wong DK, Sablon E, Tse E, Ng IO, Yuan HJ, et al. HBsAg seroclearance in chronic hepatitis B in the Chinese: virological, histological, and clinical aspects. Hepatology 2004;39:1694-1701.
-
(2004)
Hepatology
, vol.39
, pp. 1694-1701
-
-
Yuen, M.F.1
Wong, D.K.2
Sablon, E.3
Tse, E.4
Ng, I.O.5
Yuan, H.J.6
-
23
-
-
85018809066
-
Hepatitis B reactivation associated with immune suppressive and biological modifier therapies: current concepts, management strategies and future directions
-
Loomba R, Liang TJ. Hepatitis B reactivation associated with immune suppressive and biological modifier therapies: current concepts, management strategies and future directions. Gastroenterology 2017;152:1297-1309.
-
(2017)
Gastroenterology
, vol.152
, pp. 1297-1309
-
-
Loomba, R.1
Liang, T.J.2
-
24
-
-
84922621952
-
Function and information content of DNA methylation
-
Schübeler D. Function and information content of DNA methylation. Nature 2015;517:321-326.
-
(2015)
Nature
, vol.517
, pp. 321-326
-
-
Schübeler, D.1
-
25
-
-
37649007673
-
Hepatitis B viral DNA is methylated in liver tissues
-
Vivekanandan P, Thomas D, Torbenson M. Hepatitis B viral DNA is methylated in liver tissues. J Viral Hepat 2008;15:103-107.
-
(2008)
J Viral Hepat
, vol.15
, pp. 103-107
-
-
Vivekanandan, P.1
Thomas, D.2
Torbenson, M.3
-
26
-
-
84874326995
-
Comparative analysis of CpG islands among HBV genotypes
-
Zhang Y, Li C, Zhang Y, Zhu H, Kang Y, Liu H, et al. Comparative analysis of CpG islands among HBV genotypes. PLoS One 2013;8:e56711.
-
(2013)
PLoS One
, vol.8
-
-
Zhang, Y.1
Li, C.2
Zhang, Y.3
Zhu, H.4
Kang, Y.5
Liu, H.6
-
27
-
-
84908544638
-
Transcription of hepatitis B virus covalently closed circular DNA is regulated by CpG methylation during chronic infection
-
Zhang Y, Mao R, Yan R, Cai D, Zhang Y, Zhu H, et al. Transcription of hepatitis B virus covalently closed circular DNA is regulated by CpG methylation during chronic infection. PLoS One 2014;9:e110442.
-
(2014)
PLoS One
, vol.9
-
-
Zhang, Y.1
Mao, R.2
Yan, R.3
Cai, D.4
Zhang, Y.5
Zhu, H.6
-
28
-
-
84930227190
-
Comprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues
-
Jain S, Chang TT, Chen S, Boldbaatar B, Clemens A, Lin SY, et al. Comprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues. Sci Rep 2015;5:10478.
-
(2015)
Sci Rep
, vol.5
, pp. 10478
-
-
Jain, S.1
Chang, T.T.2
Chen, S.3
Boldbaatar, B.4
Clemens, A.5
Lin, S.Y.6
-
29
-
-
77950787841
-
Hepatitis B virus replication induces methylation of both host and viral DNA
-
Vivekanandan P, Daniel HD, Kannangai R, Martinez-Murillo F, Torbenson M. Hepatitis B virus replication induces methylation of both host and viral DNA. J Virol 2010;84:4321-4329.
-
(2010)
J Virol
, vol.84
, pp. 4321-4329
-
-
Vivekanandan, P.1
Daniel, H.D.2
Kannangai, R.3
Martinez-Murillo, F.4
Torbenson, M.5
-
30
-
-
84873020277
-
Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma
-
Arzumanyan A, Reis HM, Feitelson MA. Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma. Nat Rev Cancer 2013;13:123-135.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 123-135
-
-
Arzumanyan, A.1
Reis, H.M.2
Feitelson, M.A.3
-
31
-
-
0027280881
-
Methylation and imprinting: from host defense to gene regulation?
-
Barlow DP. Methylation and imprinting: from host defense to gene regulation? Science 1993;260:309-311.
-
(1993)
Science
, vol.260
, pp. 309-311
-
-
Barlow, D.P.1
-
32
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 2007;128:693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
33
-
-
36049028058
-
New nomenclature for chromatin-modifying enzymes
-
Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, et al. New nomenclature for chromatin-modifying enzymes. Cell 2007;131:633-636.
-
(2007)
Cell
, vol.131
, pp. 633-636
-
-
Allis, C.D.1
Berger, S.L.2
Cote, J.3
Dent, S.4
Jenuwien, T.5
Kouzarides, T.6
-
34
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodríguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med 2011;17:330-339.
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodríguez-Paredes, M.1
Esteller, M.2
-
35
-
-
20844450998
-
Arginine methylation: an emerging regulatorof protein function
-
Bedford MT, Richard S. Arginine methylation: an emerging regulatorof protein function. Mol Cell 2005;18:263-272.
-
(2005)
Mol Cell
, vol.18
, pp. 263-272
-
-
Bedford, M.T.1
Richard, S.2
-
36
-
-
84856514985
-
IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
-
Belloni L, Allweiss L, Guerrieri F, Pediconi N, Volz T, Pollicino T, et al. IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome. J Clin Invest 2012;122:529-537.
-
(2012)
J Clin Invest
, vol.122
, pp. 529-537
-
-
Belloni, L.1
Allweiss, L.2
Guerrieri, F.3
Pediconi, N.4
Volz, T.5
Pollicino, T.6
-
37
-
-
33644854241
-
Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones
-
Pollicino T, Belloni L, Raffa G, Pediconi N, Squadrito G, Raimondo G, et al. Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones. Gastroenterology 2006;130:823-837.
-
(2006)
Gastroenterology
, vol.130
, pp. 823-837
-
-
Pollicino, T.1
Belloni, L.2
Raffa, G.3
Pediconi, N.4
Squadrito, G.5
Raimondo, G.6
-
38
-
-
73949127893
-
Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
-
Belloni L, Pollicino T, De Nicola F, Guerrieri F, Raffa G, Fanciulli M, et al. Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function. Proc Natl Acad Sci USA 2009;106:19975-19979.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19975-19979
-
-
Belloni, L.1
Pollicino, T.2
De Nicola, F.3
Guerrieri, F.4
Raffa, G.5
Fanciulli, M.6
-
39
-
-
84875772744
-
Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription
-
Benhenda S, Ducroux A, Rivière L, Sobhian B, Ward MD, Dion S, et al. Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol 2013;87:4360-4371.
-
(2013)
J Virol
, vol.87
, pp. 4360-4371
-
-
Benhenda, S.1
Ducroux, A.2
Rivière, L.3
Sobhian, B.4
Ward, M.D.5
Dion, S.6
-
40
-
-
85020515653
-
PRMT5 restricts hepatitis B virus replication via epigenetic repression of cccDNA transcription and interference with pgRNA encapsidation
-
Zhang W, Chen J, Wu M, Zhang X, Zhang M, Yue L, et al. PRMT5 restricts hepatitis B virus replication via epigenetic repression of cccDNA transcription and interference with pgRNA encapsidation. Hepatology 2017;66:398-415.
-
(2017)
Hepatology
, vol.66
, pp. 398-415
-
-
Zhang, W.1
Chen, J.2
Wu, M.3
Zhang, X.4
Zhang, M.5
Yue, L.6
-
41
-
-
84884692876
-
Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes
-
Liu F, Campagna M, Qi Y, Zhao X, Guo F, Xu C, et al. Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes. PLoS Pathog 2013;9:e1003613.
-
(2013)
PLoS Pathog
, vol.9
-
-
Liu, F.1
Campagna, M.2
Qi, Y.3
Zhao, X.4
Guo, F.5
Xu, C.6
-
42
-
-
84947466102
-
Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation
-
Tropberger P, Mercier A, Robinson M, Zhong W, Ganem DE, Holdorf M. Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation. Proc Natl Acad Sci USA 2015;112:E5715-E5724.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E5715-E5724
-
-
Tropberger, P.1
Mercier, A.2
Robinson, M.3
Zhong, W.4
Ganem, D.E.5
Holdorf, M.6
-
43
-
-
79955551251
-
Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis
-
Ananthanarayanan M, Li Y, Surapureddi S, Balasubramaniyan N, Ahn J, Goldstein JA, et al. Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis. Am J Physiol Gastrointest Liver Physiol 2011;300:G771-G781.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, pp. G771-G781
-
-
Ananthanarayanan, M.1
Li, Y.2
Surapureddi, S.3
Balasubramaniyan, N.4
Ahn, J.5
Goldstein, J.A.6
-
44
-
-
84976295085
-
The molecular hallmarks of epigenetic control
-
Allis CD, Jenuwein T. The molecular hallmarks of epigenetic control. Nat Rev Genet 2016;17:487-500.
-
(2016)
Nat Rev Genet
, vol.17
, pp. 487-500
-
-
Allis, C.D.1
Jenuwein, T.2
-
45
-
-
84874031676
-
Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer
-
Tropberger P, Pott S, Keller C, Kamieniarz-Gdula K, Caron M, Richter F, et al. Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. Cell 2013;152:859-872.
-
(2013)
Cell
, vol.152
, pp. 859-872
-
-
Tropberger, P.1
Pott, S.2
Keller, C.3
Kamieniarz-Gdula, K.4
Caron, M.5
Richter, F.6
-
46
-
-
84964330308
-
Histone H3 globular domain acetylation identifies a new class of enhancers
-
Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GC, Schneider R, et al. Histone H3 globular domain acetylation identifies a new class of enhancers. Nat Genet 2016;48:681-686.
-
(2016)
Nat Genet
, vol.48
, pp. 681-686
-
-
Pradeepa, M.M.1
Grimes, G.R.2
Kumar, Y.3
Olley, G.4
Taylor, G.C.5
Schneider, R.6
-
47
-
-
33947528120
-
The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription
-
Cougot D, Wu Y, Cairo S, Caramel J, Renard CA, Lévy L, et al. The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription. J Biol Chem 2007;282:4277-4287.
-
(2007)
J Biol Chem
, vol.282
, pp. 4277-4287
-
-
Cougot, D.1
Wu, Y.2
Cairo, S.3
Caramel, J.4
Renard, C.A.5
Lévy, L.6
-
48
-
-
84945439538
-
HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase
-
Rivière L, Gerossier L, Ducroux A, Dion S, Deng Q, Michel ML, et al. HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase. J Hepatol 2015;63:1093-1102.
-
(2015)
J Hepatol
, vol.63
, pp. 1093-1102
-
-
Rivière, L.1
Gerossier, L.2
Ducroux, A.3
Dion, S.4
Deng, Q.5
Michel, M.L.6
-
49
-
-
84982154746
-
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor
-
Decorsière A, Mueller H, van Breugel PC, Abdul F, Gerossier L, Beran RK, et al. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature 2016;531:386-389.
-
(2016)
Nature
, vol.531
, pp. 386-389
-
-
Decorsière, A.1
Mueller, H.2
van Breugel, P.C.3
Abdul, F.4
Gerossier, L.5
Beran, R.K.6
-
50
-
-
84991690879
-
Hepatitis B virus X protein promotes degradation of SMC5/6 to enhance HBV replication
-
Murphy CM, Xu Y, Li F, Nio K, Reszka-Blanco N, Li X, et al. Hepatitis B virus X protein promotes degradation of SMC5/6 to enhance HBV replication. Cell Rep 2016;16:2846-2854.
-
(2016)
Cell Rep
, vol.16
, pp. 2846-2854
-
-
Murphy, C.M.1
Xu, Y.2
Li, F.3
Nio, K.4
Reszka-Blanco, N.5
Li, X.6
-
51
-
-
84995801665
-
Hepatitis B virus X protein crosses out Smc5/6 complex to maintain covalently closed circular DNA transcription
-
Mitra B, Guo H. Hepatitis B virus X protein crosses out Smc5/6 complex to maintain covalently closed circular DNA transcription. Hepatology 2016;64:2246-2249.
-
(2016)
Hepatology
, vol.64
, pp. 2246-2249
-
-
Mitra, B.1
Guo, H.2
-
52
-
-
84864243685
-
HIV: shock and kill
-
Deeks SG. HIV: shock and kill. Nature 2012;487:439-440.
-
(2012)
Nature
, vol.487
, pp. 439-440
-
-
Deeks, S.G.1
-
53
-
-
84863039812
-
Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents
-
Ghosh SK, Perrine SP, Williams RM, Faller DV. Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents. Blood 2012;119:1008-1017.
-
(2012)
Blood
, vol.119
, pp. 1008-1017
-
-
Ghosh, S.K.1
Perrine, S.P.2
Williams, R.M.3
Faller, D.V.4
-
54
-
-
0037455979
-
p16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis
-
Shim YH, Yoon GS, Choi HJ, Chung YH, Yu E. p16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis. Cancer Lett 2003;190:213-219.
-
(2003)
Cancer Lett
, vol.190
, pp. 213-219
-
-
Shim, Y.H.1
Yoon, G.S.2
Choi, H.J.3
Chung, Y.H.4
Yu, E.5
-
55
-
-
84877887782
-
5-Azacytidine for the treatment of myelodysplastic syndromes
-
Krawczyk J, Keane N, Freeman CL, Swords R, O'Dwyer M, Giles FJ. 5-Azacytidine for the treatment of myelodysplastic syndromes. Expert Opin Pharmacother 2013;14:1255-1268.
-
(2013)
Expert Opin Pharmacother
, vol.14
, pp. 1255-1268
-
-
Krawczyk, J.1
Keane, N.2
Freeman, C.L.3
Swords, R.4
O'Dwyer, M.5
Giles, F.J.6
-
56
-
-
84954493378
-
Epigenetic therapeutics: a new weapon in the war against cancer
-
Ahuja N, Sharma AR, Baylin SB. Epigenetic therapeutics: a new weapon in the war against cancer. Annu Rev Med 2016;67:73-89.
-
(2016)
Annu Rev Med
, vol.67
, pp. 73-89
-
-
Ahuja, N.1
Sharma, A.R.2
Baylin, S.B.3
-
58
-
-
84907985176
-
(−)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes
-
Huang HC, Tao MH, Hung TM, Chen JC, Lin ZJ, Huang C. (−)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes. Antiviral Res 2014;111:100-111.
-
(2014)
Antiviral Res
, vol.111
, pp. 100-111
-
-
Huang, H.C.1
Tao, M.H.2
Hung, T.M.3
Chen, J.C.4
Lin, Z.J.5
Huang, C.6
-
59
-
-
84970937363
-
Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication
-
Zhong L, Hu J, Shu W, Gao B, Xiong S. Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication. Cell Death Dis 2015;6:e1770.
-
(2015)
Cell Death Dis
, vol.6
-
-
Zhong, L.1
Hu, J.2
Shu, W.3
Gao, B.4
Xiong, S.5
-
60
-
-
58149310908
-
Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A
-
Zheng DL, Zhang L, Cheng N, Xu X, Deng Q, Teng XM, et al. Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. J Hepatol 2009;50:377-387.
-
(2009)
J Hepatol
, vol.50
, pp. 377-387
-
-
Zheng, D.L.1
Zhang, L.2
Cheng, N.3
Xu, X.4
Deng, Q.5
Teng, X.M.6
-
62
-
-
84971233976
-
Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators
-
Cai D, Wang X, Yan R, Mao R, Liu Y, Ji C, et al. Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators. Antiviral Res 2016;132:26-37.
-
(2016)
Antiviral Res
, vol.132
, pp. 26-37
-
-
Cai, D.1
Wang, X.2
Yan, R.3
Mao, R.4
Liu, Y.5
Ji, C.6
-
63
-
-
84908265816
-
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
-
Falkenberg KJ, Johnstone RW. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov 2014;13:673-691.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 673-691
-
-
Falkenberg, K.J.1
Johnstone, R.W.2
-
64
-
-
82955187705
-
Interferon-stimulated genes and their antiviral effector functions
-
Schoggins JW, Rice CM. Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 2011;1:519-525.
-
(2011)
Curr Opin Virol
, vol.1
, pp. 519-525
-
-
Schoggins, J.W.1
Rice, C.M.2
-
65
-
-
19944428132
-
Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial
-
Janssen HL, Van Zonneveld M, Senturk H, Zeuzem S, Akarca US, Cakaloglu Y, et al. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet 2005;365:123-129.
-
(2005)
Lancet
, vol.365
, pp. 123-129
-
-
Janssen, H.L.1
Van Zonneveld, M.2
Senturk, H.3
Zeuzem, S.4
Akarca, U.S.5
Cakaloglu, Y.6
-
66
-
-
84942162776
-
Epigenetic control of HIV-1 post integration latency: implications for therapy
-
Kumar A, Darcis G, Van Lint C, Herbein G. Epigenetic control of HIV-1 post integration latency: implications for therapy. Clin Epigenetics 2015;7:103.
-
(2015)
Clin Epigenetics
, vol.7
, pp. 103
-
-
Kumar, A.1
Darcis, G.2
Van Lint, C.3
Herbein, G.4
-
67
-
-
84896029673
-
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
-
Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, et al. Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA. Science 2014;343:1221-1228.
-
(2014)
Science
, vol.343
, pp. 1221-1228
-
-
Lucifora, J.1
Xia, Y.2
Reisinger, F.3
Zhang, K.4
Stadler, D.5
Cheng, X.6
-
68
-
-
14244254668
-
G to A hypermutation of hepatitis B virus
-
Noguchi C, Ishino H, Tsuge M, Fujimoto Y, Imamura M, Takahashi S, et al. G to A hypermutation of hepatitis B virus. Hepatology 2005;41:626-633.
-
(2005)
Hepatology
, vol.41
, pp. 626-633
-
-
Noguchi, C.1
Ishino, H.2
Tsuge, M.3
Fujimoto, Y.4
Imamura, M.5
Takahashi, S.6
-
69
-
-
84940109072
-
Targeting epigenetic processes in photodynamic therapy-induced anticancer immunity
-
Wachowska M, Muchowicz A, Golab J. Targeting epigenetic processes in photodynamic therapy-induced anticancer immunity. Front Oncol 2015;5:176.
-
(2015)
Front Oncol
, vol.5
, pp. 176
-
-
Wachowska, M.1
Muchowicz, A.2
Golab, J.3
-
70
-
-
84879211454
-
T-cell memory differentiation: Insights from transcriptional signatures and epigenetics
-
Youngblood B, Hale JS, Ahmed R. T-cell memory differentiation: Insights from transcriptional signatures and epigenetics. Immunology 2013;139:277-284.
-
(2013)
Immunology
, vol.139
, pp. 277-284
-
-
Youngblood, B.1
Hale, J.S.2
Ahmed, R.3
-
71
-
-
84896820241
-
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
-
Li H, Chiappinelli KB, Guzzetta A, Easwaran H, Yen RW, Vatapalli R, et al. Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers. Oncotarget 2014;5:587-598.
-
(2014)
Oncotarget
, vol.5
, pp. 587-598
-
-
Li, H.1
Chiappinelli, K.B.2
Guzzetta, A.3
Easwaran, H.4
Yen, R.W.5
Vatapalli, R.6
-
72
-
-
51649092609
-
Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines
-
Buglio D, Georgakis GV, Hanabuchi S, Arima K, Khaskhely NM, Liu YJ, et al. Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines. Blood 2008;112:1424-1433.
-
(2008)
Blood
, vol.112
, pp. 1424-1433
-
-
Buglio, D.1
Georgakis, G.V.2
Hanabuchi, S.3
Arima, K.4
Khaskhely, N.M.5
Liu, Y.J.6
-
73
-
-
79953084657
-
HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma
-
Buglio D, Khaskhely NM, Voo KS, Martinez-Valdez H, Liu YJ, Younes A. HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma. Blood 2011;117:2910-2917.
-
(2011)
Blood
, vol.117
, pp. 2910-2917
-
-
Buglio, D.1
Khaskhely, N.M.2
Voo, K.S.3
Martinez-Valdez, H.4
Liu, Y.J.5
Younes, A.6
-
74
-
-
84952684286
-
Interferon-γ and tumor necrosis factor-α produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis
-
Xia Y, Stadler D, Lucifora J, Reisinger F, Webb D, Hösel M, et al. Interferon-γ and tumor necrosis factor-α produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis. Gastroenterology 2016;150:194-205.
-
(2016)
Gastroenterology
, vol.150
, pp. 194-205
-
-
Xia, Y.1
Stadler, D.2
Lucifora, J.3
Reisinger, F.4
Webb, D.5
Hösel, M.6
|