메뉴 건너뛰기




Volumn 190, Issue 2, 2003, Pages 213-219

p16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis

Author keywords

Cirrhotic nodule; Dysplastic nodule; Early hepatocellular carcinoma; Hepatitis B virus infection; Multistep carcinogenesis; p16 hypermethylation

Indexed keywords

PARAFFIN; PROTEIN P16;

EID: 0037455979     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00613-4     Document Type: Article
Times cited : (76)

References (38)
  • 1
    • 0028898433 scopus 로고
    • Macroregenerative nodules in a series of adult cirrhotic liver explants: Issues of classification and nomenclature
    • Hytiroglou P., Theise N.D., Schwartz M., Mor E., Miller C., Thung S.N. Macroregenerative nodules in a series of adult cirrhotic liver explants: Issues of classification and nomenclature. Hepatology. 21:1995;703-708.
    • (1995) Hepatology , vol.21 , pp. 703-708
    • Hytiroglou, P.1    Theise, N.D.2    Schwartz, M.3    Mor, E.4    Miller, C.5    Thung, S.N.6
  • 2
    • 0028824044 scopus 로고
    • Macroregenerative (dysplastic) nodules and hepatocarcinogenesis: Theoretical and clinical considerations
    • Theise N.D. Macroregenerative (dysplastic) nodules and hepatocarcinogenesis: theoretical and clinical considerations. Semin. Liver Dis. 15:1995;360-371.
    • (1995) Semin. Liver Dis. , vol.15 , pp. 360-371
    • Theise, N.D.1
  • 3
    • 0029155354 scopus 로고
    • Terminology of nodular hepatocellular lesions
    • Terminology of nodular hepatocellular lesions. Hepatology. 22:1995;983-993.
    • (1995) Hepatology , vol.22 , pp. 983-993
  • 4
    • 0031730060 scopus 로고    scopus 로고
    • Differential diagnosis of hepatocellular nodular lesions
    • Hytiroglou P., Theise N.D. Differential diagnosis of hepatocellular nodular lesions. Semin. Diagn. Pathol. 15:1998;285-299.
    • (1998) Semin. Diagn. Pathol. , vol.15 , pp. 285-299
    • Hytiroglou, P.1    Theise, N.D.2
  • 5
    • 0031019406 scopus 로고    scopus 로고
    • Early hepatocellular carcinoma macroscopically resembling adenomatous hyperplasia: Pathological resemblance to carcinoma-in-situ
    • Wakasa K., Haba T., Hamada T., Sasaki M., Sakurai M. Early hepatocellular carcinoma macroscopically resembling adenomatous hyperplasia: pathological resemblance to carcinoma-in-situ. Pathol. Int. 47:1997;54-59.
    • (1997) Pathol. Int. , vol.47 , pp. 54-59
    • Wakasa, K.1    Haba, T.2    Hamada, T.3    Sasaki, M.4    Sakurai, M.5
  • 6
    • 0032187919 scopus 로고    scopus 로고
    • Natural history and prognosis of adenomatous hyperplasia and early hepatocellular carcinoma: Multi-institutional analysis of 53 nodules followed up for more than 6 months and 141 patients with single early hepatocellular carcinoma treated by surgical resection or percutaneous ethanol injection
    • Sakamoto M., Hirohashi S. Natural history and prognosis of adenomatous hyperplasia and early hepatocellular carcinoma: multi-institutional analysis of 53 nodules followed up for more than 6 months and 141 patients with single early hepatocellular carcinoma treated by surgical resection or percutaneous ethanol injection. Jpn. J. Clin. Oncol. 28:1998;604-608.
    • (1998) Jpn. J. Clin. Oncol. , vol.28 , pp. 604-608
    • Sakamoto, M.1    Hirohashi, S.2
  • 7
    • 0032857415 scopus 로고    scopus 로고
    • Molecular basis of multistep hepatocarcinogenesis: Genetic and epigenetic event
    • Hui A.M. Molecular basis of multistep hepatocarcinogenesis: genetic and epigenetic event. Scand. J. Gastroenterol. 8:1999;738-742.
    • (1999) Scand. J. Gastroenterol. , vol.8 , pp. 738-742
    • Hui, A.M.1
  • 8
    • 0028306247 scopus 로고
    • Molecular events in the pathogenesis of hepadna virus-associated hepatocellular carcinoma
    • Robinson W.S. Molecular events in the pathogenesis of hepadna virus-associated hepatocellular carcinoma. Annu. Rev. Med. 45:1994;297-323.
    • (1994) Annu. Rev. Med. , vol.45 , pp. 297-323
    • Robinson, W.S.1
  • 9
    • 0026041836 scopus 로고
    • Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas
    • Murakami Y., Hayashi K., Hirohashi S., Sekiya T. Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res. 51:1991;5520-5525.
    • (1991) Cancer Res. , vol.51 , pp. 5520-5525
    • Murakami, Y.1    Hayashi, K.2    Hirohashi, S.3    Sekiya, T.4
  • 10
    • 0030849123 scopus 로고    scopus 로고
    • Comprehensive allelotyping of human hepatocellular carcinoma
    • Nagai H., Pineau P., Tiollais P., Buendia M.A., Dejean A. Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene. 14:1997;2927-2933.
    • (1997) Oncogene , vol.14 , pp. 2927-2933
    • Nagai, H.1    Pineau, P.2    Tiollais, P.3    Buendia, M.A.4    Dejean, A.5
  • 11
    • 0032484502 scopus 로고    scopus 로고
    • Allelotype analysis of hepatocellular carcinoma
    • Piao Z., Park C., Park J.H., Kim H. Allelotype analysis of hepatocellular carcinoma. Int. J. Cancer. 75:1998;29-33.
    • (1998) Int. J. Cancer , vol.75 , pp. 29-33
    • Piao, Z.1    Park, C.2    Park, J.H.3    Kim, H.4
  • 12
    • 0033988602 scopus 로고    scopus 로고
    • Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis
    • Kanai Y., Ushijima S., Tsuda H., Sakamoto S. Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis. Cancer Lett. 148:2000;73-80.
    • (2000) Cancer Lett. , vol.148 , pp. 73-80
    • Kanai, Y.1    Ushijima, S.2    Tsuda, H.3    Sakamoto, S.4
  • 13
    • 0033765496 scopus 로고    scopus 로고
    • Gene instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma
    • Kondo Y., Kanai Y., Skamoto M., Mizokame M., Ueda R., Hirohashi S. Gene instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology. 32:2000;970-979.
    • (2000) Hepatology , vol.32 , pp. 970-979
    • Kondo, Y.1    Kanai, Y.2    Skamoto, M.3    Mizokame, M.4    Ueda, R.5    Hirohashi, S.6
  • 14
    • 0028027208 scopus 로고
    • Different mutations of the p53 gene in nodule-in-nodule hepatocellular carcinoma as an evidence for multistage progression
    • Oda T., Tsuda H., Sakamoto M., Hiroshi S. Different mutations of the p53 gene in nodule-in-nodule hepatocellular carcinoma as an evidence for multistage progression. Cancer Lett. 83:1994;197-200.
    • (1994) Cancer Lett. , vol.83 , pp. 197-200
    • Oda, T.1    Tsuda, H.2    Sakamoto, M.3    Hiroshi, S.4
  • 15
    • 0030013351 scopus 로고    scopus 로고
    • Comparison of the proliferative capacity of adenomatous hyperplasia and well differentiated hepatocellular carcinoma
    • Yamashita A. Comparison of the proliferative capacity of adenomatous hyperplasia and well differentiated hepatocellular carcinoma. J. Gastroenterol. 31:1996;373-378.
    • (1996) J. Gastroenterol. , vol.31 , pp. 373-378
    • Yamashita, A.1
  • 17
    • 0031931851 scopus 로고    scopus 로고
    • P53 mutation and overexpression in hepatocellular carcinoma and dysplastic nodules in the liver
    • Kang Y.K., Kim C.J., Kim W.H., Kim H.O., Kang G.H., Kim Y.I. p53 mutation and overexpression in hepatocellular carcinoma and dysplastic nodules in the liver. Virchows Arch. 432:1998;27-32.
    • (1998) Virchows Arch. , vol.432 , pp. 27-32
    • Kang, Y.K.1    Kim, C.J.2    Kim, W.H.3    Kim, H.O.4    Kang, G.H.5    Kim, Y.I.6
  • 18
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter T., Pines J. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell. 79:1994;573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 19
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 21
    • 0344301900 scopus 로고    scopus 로고
    • Role of the p16 tumor suppressor gene in cancer
    • Liggett W.H., Sidransky D. Role of the p16 tumor suppressor gene in cancer. J. Clin. Oncol. 16:1998;1197-1206.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1197-1206
    • Liggett, W.H.1    Sidransky, D.2
  • 22
    • 0034077361 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in carcinogenesis
    • Sugimura T., Ushijima T. Genetic and epigenetic alterations in carcinogenesis. Mutat. Res. 462:2000;235-246.
    • (2000) Mutat. Res. , vol.462 , pp. 235-246
    • Sugimura, T.1    Ushijima, T.2
  • 24
    • 0031043705 scopus 로고    scopus 로고
    • Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population
    • Biden K., Young J., Buttenshaw R., Searle J., Cooksley G., Xu D.B., Leggett B. Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population. Hepatology. 25:1997;593-597.
    • (1997) Hepatology , vol.25 , pp. 593-597
    • Biden, K.1    Young, J.2    Buttenshaw, R.3    Searle, J.4    Cooksley, G.5    Xu, D.B.6    Leggett, B.7
  • 26
    • 0031736810 scopus 로고    scopus 로고
    • Correlation between DNA methylation and pathological changes in human hepatocellular carcinoma
    • Shen L., Fang J., Qiu D., Zgang T., Yang J., Chen D.S., Xiao S. Correlation between DNA methylation and pathological changes in human hepatocellular carcinoma. Hepato-Gastroenterology. 45:1998;1753-1759.
    • (1998) Hepato-Gastroenterology , vol.45 , pp. 1753-1759
    • Shen, L.1    Fang, J.2    Qiu, D.3    Zgang, T.4    Yang, J.5    Chen, D.S.6    Xiao, S.7
  • 28
    • 0032924622 scopus 로고    scopus 로고
    • P16INK4 is inactivated by extensive CpG methylation in human hepatocellular carcinoma
    • Matsuda Y., Ichida T., Matsuzawa J., Sugimura K., Asakura H. p16INK4 is inactivated by extensive CpG methylation in human hepatocellular carcinoma. Gastroenterology. 116:1999;394-400.
    • (1999) Gastroenterology , vol.116 , pp. 394-400
    • Matsuda, Y.1    Ichida, T.2    Matsuzawa, J.3    Sugimura, K.4    Asakura, H.5
  • 30
    • 0035266345 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: Identification of gene involved in viral carcinogenesis and tumor progression
    • Okabe H., Satoh S., Kato T., Kitahara O., Yanagawa R., Yamaoka Y., Tsunoda T., Furukawa Y., Nakamura Y. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of gene involved in viral carcinogenesis and tumor progression. Cancer Res. 61:2001;2129-2137.
    • (2001) Cancer Res. , vol.61 , pp. 2129-2137
    • Okabe, H.1    Satoh, S.2    Kato, T.3    Kitahara, O.4    Yanagawa, R.5    Yamaoka, Y.6    Tsunoda, T.7    Furukawa, Y.8    Nakamura, Y.9
  • 31
    • 0000934401 scopus 로고
    • Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA
    • Sells M.A., Chen M.L., Acs G. Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA. Proc. Natl. Acad. Sci. USA. 84:1987;1005-1009.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1005-1009
    • Sells, M.A.1    Chen, M.L.2    Acs, G.3
  • 34
    • 0342748644 scopus 로고    scopus 로고
    • Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas
    • Shim Y.H., Kang G.H., Ro J.Y. Correlation of p16 hypermethylation with p16 protein loss in sporadic gastric carcinomas. Lab. Invest. 80:2000;689-695.
    • (2000) Lab. Invest. , vol.80 , pp. 689-695
    • Shim, Y.H.1    Kang, G.H.2    Ro, J.Y.3
  • 35
    • 0029050539 scopus 로고
    • Chromosomal insertion of foreign (adenovirus typer 12, plasmid, or bacteriophage λ) DNA is associated with enhanced methylation of cellular DNA segments
    • Heller H., Kammer C., Wilgenbus P., Doerfler W. Chromosomal insertion of foreign (adenovirus typer 12, plasmid, or bacteriophage λ) DNA is associated with enhanced methylation of cellular DNA segments. Proc. Natl. Acad. Sci. USA. 92:1995;5515-5519.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5515-5519
    • Heller, H.1    Kammer, C.2    Wilgenbus, P.3    Doerfler, W.4
  • 36
    • 0345435970 scopus 로고    scopus 로고
    • Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences
    • Remus R., Kammer C., Heller H., Schmitz B., Schell G., Doerfler W. Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences. J. Virol. 73:1999;1010-1022.
    • (1999) J. Virol. , vol.73 , pp. 1010-1022
    • Remus, R.1    Kammer, C.2    Heller, H.3    Schmitz, B.4    Schell, G.5    Doerfler, W.6
  • 37
    • 0023723658 scopus 로고
    • A case-control study of primary hepatocellular carcinoma in Taiwan
    • Lu S.N., Lin T.M., Chen C.J. A case-control study of primary hepatocellular carcinoma in Taiwan. Cancer. 62:1988;2051-2055.
    • (1988) Cancer , vol.62 , pp. 2051-2055
    • Lu, S.N.1    Lin, T.M.2    Chen, C.J.3
  • 38
    • 0343953594 scopus 로고    scopus 로고
    • Hypermethylation can selectively silence individual p16INK4A alleles in neoplasia
    • Myohanen S.K., Baylin S.B., Herman J.G. Hypermethylation can selectively silence individual p16INK4A alleles in neoplasia. Cancer Res. 58:1998;591-593.
    • (1998) Cancer Res. , vol.58 , pp. 591-593
    • Myohanen, S.K.1    Baylin, S.B.2    Herman, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.