Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication

Cell Reports

Volumn 16, Issue 11, 2016, Pages 2846-2854

  Murphy, Christopher M ^a,b   Xu, Yanping ^a,b   Li, Feng ^a,b   Nio, Kouki ^a,b   Reszka Blanco, Natalia ^a,b   Li, Xiaodong ^a,b   Wu, Yaxu ^a,b   Yu, Yanbao ^c   Xiong, Yue ^a,b   Su, Lishan ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c J CRAIG VENTER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHROMOSOME PROTEIN; CIRCULAR DNA; CULLIN; CULLIN 4; DDB1 PROTEIN; HEPATITIS B VIRUS X PROTEIN; MINICIRCLE DNA; PROTEASOME; ROC1 PROTEIN; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS DNA; CELL CYCLE PROTEIN; CRL4 PROTEIN, HUMAN; PROTEIN BINDING; SMC5 PROTEIN, HUMAN; SMC6 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GENE SILENCING; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEOMICS; UBIQUITINATION; VIRUS GENE; VIRUS GENOME; VIRUS REPLICATION; ANIMAL; ENZYME SPECIFICITY; GENETICS; HEK293 CELL LINE; HEP-G2 CELL LINE; LIVER; METABOLISM; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ANIMALS; CELL CYCLE PROTEINS; GENE EXPRESSION REGULATION, VIRAL; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HEP G2 CELLS; HEPATITIS B; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; LIVER; MICE; PROTEIN BINDING; PROTEOLYSIS; PROTEOMICS; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRUS REPLICATION;

EID: 84991690879     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.026     Document Type: Article

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