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Volumn 531, Issue 7594, 2016, Pages 386-389

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

Author keywords

[No Author keywords available]

Indexed keywords

DDB1 E3 UBIQUITIN LIGASE; EXTRACHROMOSOMAL DNA; HEPATITIS B VIRUS X PROTEIN; STRUCTURAL MAINTENANCE OF CHROMOSOME 5; STRUCTURAL MAINTENANCE OF CHROMOSOME 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; PROTEIN BINDING; SMC5 PROTEIN, HUMAN; SMC6 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; VIRUS DNA;

EID: 84982154746     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17170     Document Type: Article
Times cited : (410)

References (44)
  • 2
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection - Natural history and clinical consequences
    • Ganem, D., & Prince, A. M. Hepatitis B virus infection - natural history and clinical consequences. N. Engl. J. Med. 350, 1118-1129 (2004
    • (2004) N. Engl. J. Med , vol.350 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 3
    • 71149108706 scopus 로고    scopus 로고
    • Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis
    • Benhenda, S., Cougot, D., Buendia, M. A., & Neuveut, C. Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis. Adv. Cancer Res. 103, 75-109 (2009
    • (2009) Adv. Cancer Res , vol.103 , pp. 75-109
    • Benhenda, S.1    Cougot, D.2    Buendia, M.A.3    Neuveut, C.4
  • 4
    • 79957614798 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection
    • Lucifora, J., et al. Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection. J. Hepatol. 55, 996-1003 (2011
    • (2011) J. Hepatol , vol.55 , pp. 996-1003
    • Lucifora, J.1
  • 5
    • 84894133577 scopus 로고    scopus 로고
    • The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease
    • Feitelson, M. A., Bonamassa, B., & Arzumanyan, A. The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease. Expert Opin. Ther. Targets 18, 293-306 (2014
    • (2014) Expert Opin. Ther. Targets , vol.18 , pp. 293-306
    • Feitelson, M.A.1    Bonamassa, B.2    Arzumanyan, A.3
  • 6
    • 84870522970 scopus 로고    scopus 로고
    • Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates
    • van Breugel, P. C., et al. Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates. Hepatology 56, 2116-2124 (2012
    • (2012) Hepatology , vol.56 , pp. 2116-2124
    • Van Breugel, P.C.1
  • 7
    • 15244357567 scopus 로고    scopus 로고
    • Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death
    • Leupin, O., Bontron, S., Schaeffer, C., & Strubin, M. Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death. J. Virol. 79, 4238-4245 (2005
    • (2005) J. Virol , vol.79 , pp. 4238-4245
    • Leupin, O.1    Bontron, S.2    Schaeffer, C.3    Strubin, M.4
  • 8
    • 77449113802 scopus 로고    scopus 로고
    • A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery
    • Li, T., Robert, E. I., van Breugel, P. C., Strubin, M., & Zheng, N. A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nature Struct. Mol. Biol. 17, 105-111 (2010
    • (2010) Nature Struct. Mol. Biol , vol.17 , pp. 105-111
    • Li, T.1    Robert, E.I.2    Van Breugel, P.C.3    Strubin, M.4    Zheng, N.5
  • 9
    • 84857721968 scopus 로고    scopus 로고
    • Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication
    • Hodgson, A. J., Hyser, J. M., Keasler, V. V., Cang, Y., & Slagle, B. L. Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication. Virology 426, 73-82 (2012
    • (2012) Virology , vol.426 , pp. 73-82
    • Hodgson, A.J.1    Hyser, J.M.2    Keasler, V.V.3    Cang, Y.4    Slagle, B.L.5
  • 10
    • 0034618405 scopus 로고    scopus 로고
    • UVDDB p127-binding modulates activities and intracellular distribution of hepatitis B virus X protein
    • Sitterlin, D., Bergametti, F., & Transy, C. UVDDB p127-binding modulates activities and intracellular distribution of hepatitis B virus X protein. Oncogene 19, 4417-4426 (2000
    • (2000) Oncogene , vol.19 , pp. 4417-4426
    • Sitterlin, D.1    Bergametti, F.2    Transy, C.3
  • 11
    • 0036942290 scopus 로고    scopus 로고
    • Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components
    • Ulane, C. M., & Horvath, C. M. Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components. Virology 304, 160-166 (2002
    • (2002) Virology , vol.304 , pp. 160-166
    • Ulane, C.M.1    Horvath, C.M.2
  • 12
    • 27144433162 scopus 로고    scopus 로고
    • Simian virus 5 v protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1
    • Precious, B., Childs, K., Fitzpatrick-Swallow, V., Goodbourn, S., & Randall, R. E. Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1. J. Virol. 79, 13434-13441 (2005
    • (2005) J. Virol , vol.79 , pp. 13434-13441
    • Precious, B.1    Childs, K.2    Fitzpatrick-Swallow, V.3    Goodbourn, S.4    Randall, R.E.5
  • 13
    • 0038365225 scopus 로고    scopus 로고
    • Hepatitis B virus X protein and simian virus 5 v protein exhibit similar UV-DDB1 binding properties to mediate distinct activities
    • Leupin, O., Bontron, S., & Strubin, M. Hepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activities. J. Virol. 77, 6274-6283 (2003
    • (2003) J. Virol , vol.77 , pp. 6274-6283
    • Leupin, O.1    Bontron, S.2    Strubin, M.3
  • 14
    • 84875772744 scopus 로고    scopus 로고
    • Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription
    • Benhenda, S., et al. Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J. Virol. 87, 4360-4371 (2013
    • (2013) J. Virol , vol.87 , pp. 4360-4371
    • Benhenda, S.1
  • 15
    • 38549138271 scopus 로고    scopus 로고
    • Smc5/6: A link between DNA repair and unidirectional replication?
    • Murray, J. M., & Carr, A. M. Smc5/6: a link between DNA repair and unidirectional replication?. Nature Rev. Mol. Cell Biol. 9, 177-182 (2008
    • (2008) Nature Rev. Mol. Cell Biol , vol.9 , pp. 177-182
    • Murray, J.M.1    Carr, A.M.2
  • 16
    • 63049134689 scopus 로고    scopus 로고
    • The unnamed complex: What do we know about Smc5-Smc6?
    • De Piccoli, G., Torres-Rosell, J., & Aragón, L. The unnamed complex: what do we know about Smc5-Smc6?. Chromosome Res. 17, 251-263 (2009
    • (2009) Chromosome Res , vol.17 , pp. 251-263
    • De Piccoli, G.1    Torres-Rosell, J.2    Aragón, L.3
  • 17
    • 84906704724 scopus 로고    scopus 로고
    • The maintenance of chromosome structure: Positioning and functioning of SMC complexes
    • Jeppsson, K., Kanno, T., Shirahige, K., & Sjögren, C. The maintenance of chromosome structure: positioning and functioning of SMC complexes. Nature Rev. Mol. Cell Biol. 15, 601-614 (2014
    • (2014) Nature Rev. Mol. Cell Biol , vol.15 , pp. 601-614
    • Jeppsson, K.1    Kanno, T.2    Shirahige, K.3    Sjögren, C.4
  • 18
    • 77956042333 scopus 로고    scopus 로고
    • Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo
    • Zhang, Z., Sun, E., Ou, J. H., & Liang, T. J. Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo. J. Virol. 84, 9326-9331 (2010
    • (2010) J. Virol , vol.84 , pp. 9326-9331
    • Zhang, Z.1    Sun, E.2    Ou, J.H.3    Liang, T.J.4
  • 19
    • 64749098830 scopus 로고    scopus 로고
    • An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
    • Soucy, T. A., et al. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature 458, 732-736 (2009
    • (2009) Nature , vol.458 , pp. 732-736
    • Soucy, T.A.1
  • 20
    • 80054694510 scopus 로고    scopus 로고
    • Global identification of modular cullin-RING ligase substrates
    • Emanuele, M. J., et al. Global identification of modular cullin-RING ligase substrates. Cell 147, 459-474 (2011
    • (2011) Cell , vol.147 , pp. 459-474
    • Emanuele, M.J.1
  • 21
    • 38949143250 scopus 로고    scopus 로고
    • Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex
    • Taylor, E. M., Copsey, A. C., Hudson, J. J., Vidot, S., & Lehmann, A. R. Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. Mol. Cell. Biol. 28, 1197-1206 (2008
    • (2008) Mol. Cell. Biol , vol.28 , pp. 1197-1206
    • Taylor, E.M.1    Copsey, A.C.2    Hudson, J.J.3    Vidot, S.4    Lehmann, A.R.5
  • 23
    • 33746515537 scopus 로고    scopus 로고
    • Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
    • Potts, P. R., Porteus, M. H., & Yu, H. Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J. 25, 3377-3388 (2006
    • (2006) EMBO J. , vol.25 , pp. 3377-3388
    • Potts, P.R.1    Porteus, M.H.2    Yu, H.3
  • 24
    • 84929518935 scopus 로고    scopus 로고
    • Functional interplay between cohesin and Smc5/6 complexes
    • Tapia-Alveal, C., Lin, S. J., & O?Connell, M. J. Functional interplay between cohesin and Smc5/6 complexes. Chromosoma 123, 437-445 (2014
    • (2014) Chromosoma , vol.123 , pp. 437-445
    • Tapia-Alveal, C.1    Lin, S.J.2    Oconnell, M.J.3
  • 25
    • 84940793917 scopus 로고    scopus 로고
    • The Smc5/6 complex is an ATP-dependent intermolecular DNA linker
    • Kanno, T., Berta, D. G., & Sjögren, C. The Smc5/6 complex is an ATP-dependent intermolecular DNA linker. Cell Reports 12, 1471-1482 (2015
    • (2015) Cell Reports , vol.12 , pp. 1471-1482
    • Kanno, T.1    Berta, D.G.2    Sjögren, C.3
  • 27
    • 33646177549 scopus 로고    scopus 로고
    • At the heart of the chromosome: SMC proteins in action
    • Hirano, T. At the heart of the chromosome: SMC proteins in action. Nature Rev. Mol. Cell Biol. 7, 311-322 (2006
    • (2006) Nature Rev. Mol. Cell Biol , vol.7 , pp. 311-322
    • Hirano, T.1
  • 28
    • 0035450252 scopus 로고    scopus 로고
    • Hepatitis B virus X protein interferes with cell viability through interaction with the p127-kDa UV-damaged DNA-binding protein
    • Lin-Marq, N., Bontron, S., Leupin, O., & Strubin, M. Hepatitis B virus X protein interferes with cell viability through interaction with the p127-kDa UV-damaged DNA-binding protein. Virology 287, 266-274 (2001
    • (2001) Virology , vol.287 , pp. 266-274
    • Lin-Marq, N.1    Bontron, S.2    Leupin, O.3    Strubin, M.4
  • 29
    • 37048999786 scopus 로고    scopus 로고
    • A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes
    • Gloeckner, C. J., Boldt, K., Schumacher, A., Roepman, R., & Ueffing, M. A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes. Proteomics 7, 4228-4234 (2007
    • (2007) Proteomics , vol.7 , pp. 4228-4234
    • Gloeckner, C.J.1    Boldt, K.2    Schumacher, A.3    Roepman, R.4    Ueffing, M.5
  • 30
    • 0037064038 scopus 로고    scopus 로고
    • Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2
    • Bontron, S., Lin-Marq, N., & Strubin, M. Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2. J. Biol. Chem. 277, 38847-38854 (2002
    • (2002) J. Biol. Chem , vol.277 , pp. 38847-38854
    • Bontron, S.1    Lin-Marq, N.2    Strubin, M.3
  • 31
    • 79952303452 scopus 로고    scopus 로고
    • The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
    • Meerbrey, K. L., et al. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc. Natl Acad. Sci. USA 108, 3665-3670 (2011
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 3665-3670
    • Meerbrey, K.L.1
  • 32
    • 82655186588 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus
    • De Iaco, A., & Luban, J. Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus. Retrovirology 8, 98 (2011
    • (2011) Retrovirology , vol.8 , pp. 98
    • De Iaco, A.1    Luban, J.2
  • 33
    • 33644819774 scopus 로고    scopus 로고
    • Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes
    • Goldring, C. E., et al. Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes. Am. J. Physiol. Cell Physiol. 290, C104-C115 (2006
    • (2006) Am. J. Physiol. Cell Physiol , vol.290 , pp. C104-C115
    • Goldring, C.E.1
  • 34
    • 59849105037 scopus 로고    scopus 로고
    • Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells
    • Hantz, O., et al. Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells. J. Gen. Virol. 90, 127-135 (2009
    • (2009) J. Gen. Virol , vol.90 , pp. 127-135
    • Hantz, O.1
  • 35
    • 0030842540 scopus 로고    scopus 로고
    • Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: A novel system for screening potential inhibitors of HBV replication
    • Ladner, S. K., et al. Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication. Antimicrob. Agents Chemother. 41, 1715-1720 (1997
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 1715-1720
    • Ladner, S.K.1
  • 36
    • 64749107970 scopus 로고    scopus 로고
    • Production concentration and titration of pseudotyped HIV-1-based lentiviral vectors
    • Kutner, R. H., Zhang, X. Y., & Reiser, J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nature Protocols 4, 495-505 (2009
    • (2009) Nature Protocols , vol.4 , pp. 495-505
    • Kutner, R.H.1    Zhang, X.Y.2    Reiser, J.3
  • 37
    • 84859589642 scopus 로고    scopus 로고
    • Epidermal growth factor improves lentivirus vector gene transfer into primary mouse hepatocytes
    • Rothe, M., et al. Epidermal growth factor improves lentivirus vector gene transfer into primary mouse hepatocytes. Gene Ther. 19, 425-434 (2012
    • (2012) Gene Ther , vol.19 , pp. 425-434
    • Rothe, M.1
  • 38
    • 56149087784 scopus 로고    scopus 로고
    • Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1
    • Martin-Lluesma, S., et al. Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1. Hepatology 48, 1467-1476 (2008
    • (2008) Hepatology , vol.48 , pp. 1467-1476
    • Martin-Lluesma, S.1
  • 39
    • 0035167402 scopus 로고    scopus 로고
    • Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex
    • Taylor, E. M., et al. Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex. Mol. Biol. Cell 12, 1583-1594 (2001
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1583-1594
    • Taylor, E.M.1
  • 40
    • 0026080984 scopus 로고
    • Correlation between HBV DNA detection by polymerase chain reaction and Pre-S1 antigenemia in symptomatic and asymptomatic hepatitis B virus infections
    • Chemin, I., et al. Correlation between HBV DNA detection by polymerase chain reaction and Pre-S1 antigenemia in symptomatic and asymptomatic hepatitis B virus infections. J. Med. Virol. 33, 51-57 (1991
    • (1991) J. Med. Virol , vol.33 , pp. 51-57
    • Chemin, I.1
  • 41
    • 0027221167 scopus 로고
    • Reproducible high level infection of cultured adult human hepatocytes by hepatitis B virus: Effect of polyethylene glycol on adsorption and penetration
    • Gripon, P., Diot, C., & Guguen-Guillouzo, C. Reproducible high level infection of cultured adult human hepatocytes by hepatitis B virus: effect of polyethylene glycol on adsorption and penetration. Virology 192, 534-540 (1993
    • (1993) Virology , vol.192 , pp. 534-540
    • Gripon, P.1    Diot, C.2    Guguen-Guillouzo, C.3
  • 42
    • 84864832632 scopus 로고    scopus 로고
    • A novel animal model for in vivo study of liver cancer metastasis
    • Fujiwara, S., et al. A novel animal model for in vivo study of liver cancer metastasis. World J. Gastroenterol. 18, 3875-3882 (2012
    • (2012) World J. Gastroenterol , vol.18 , pp. 3875-3882
    • Fujiwara, S.1
  • 43
    • 84928037100 scopus 로고    scopus 로고
    • Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice
    • Ishida, Y., et al. Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice. Am. J. Pathol. 185, 1275-1285 (2015
    • (2015) Am. J. Pathol , vol.185 , pp. 1275-1285
    • Ishida, Y.1
  • 44
    • 10344259136 scopus 로고    scopus 로고
    • The v proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
    • Andrejeva, J., et al. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc. Natl Acad. Sci. USA 101, 17264-17269 (2004
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 17264-17269
    • Andrejeva, J.1


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