-
1
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol 2013; 15: 713-720.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
3
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011; 469: 323-335.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
4
-
-
84865451717
-
Novel pharmacological modulators of autophagy and therapeutic prospects
-
Bischoff P, Josset E, Dumont FJ. Novel pharmacological modulators of autophagy and therapeutic prospects. Expert Opin Ther Pat 2012; 22: 1053-1079.
-
(2012)
Expert Opin Ther Pat
, vol.22
, pp. 1053-1079
-
-
Bischoff, P.1
Josset, E.2
Dumont, F.J.3
-
5
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
Rubinsztein DC, Codogno P, Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Discov 2012; 11: 709-730.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
6
-
-
84901833411
-
Autophagy and human disease: Emerging themes
-
Schneider JL, Cuervo AM. Autophagy and human disease: emerging themes. Curr Opin Genet Dev 2014; 26C: 16-23.
-
(2014)
Curr Opin Genet Dev
, vol.26 C
, pp. 16-23
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
8
-
-
84873031729
-
Inhibition of cellular autophagy deranges dengue virion maturation
-
Mateo R, Nagamine CM, Spagnolo J, Méndez E, Rahe M, Gale M Jr et al. Inhibition of cellular autophagy deranges dengue virion maturation. J Virol 2013; 87: 1312-1321.
-
(2013)
J Virol
, vol.87
, pp. 1312-1321
-
-
Mateo, R.1
Nagamine, C.M.2
Spagnolo, J.3
Méndez, E.4
Rahe, M.5
Gale, M.6
-
9
-
-
84892808155
-
Coxsackievirus B3-induced calpain activation facilitates the progeny virus replication via a likely mechanism related with both autophagy enhancement and apoptosis inhibition in the early phase of infection: An in vitro study in H9c2 cells
-
Li M, Wang X, Yu Y, Yu Y, Xie Y, Zou Y et al. Coxsackievirus B3-induced calpain activation facilitates the progeny virus replication via a likely mechanism related with both autophagy enhancement and apoptosis inhibition in the early phase of infection: an in vitro study in H9c2 cells. Virus Res 2014; 179: 177-186.
-
(2014)
Virus Res
, vol.179
, pp. 177-186
-
-
Li, M.1
Wang, X.2
Yu, Y.3
Yu, Y.4
Xie, Y.5
Zou, Y.6
-
10
-
-
78650961487
-
Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro
-
Ke PY, Chen SS. Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. J Clin Invest 2011; 121: 37-56.
-
(2011)
J Clin Invest
, vol.121
, pp. 37-56
-
-
Ke, P.Y.1
Chen, S.S.2
-
11
-
-
84893969715
-
A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability
-
Beale R, Wise H, Stuart A, Ravenhill BJ, Digard P, Randow F. A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability. Cell Host Microbe 2014; 15: 239-247.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 239-247
-
-
Beale, R.1
Wise, H.2
Stuart, A.3
Ravenhill, B.J.4
Digard, P.5
Randow, F.6
-
12
-
-
84873733623
-
Autophagy in antiviral innate immunity
-
Richetta C, Faure M. Autophagy in antiviral innate immunity. Cell Microbiol 2013; 15: 368-376.
-
(2013)
Cell Microbiol
, vol.15
, pp. 368-376
-
-
Richetta, C.1
Faure, M.2
-
13
-
-
58949098335
-
Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression
-
Tang H, Da L, Mao Y, Li Y, Li D, Xu Z et al. Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology 2009; 49: 60-71.
-
(2009)
Hepatology
, vol.49
, pp. 60-71
-
-
Tang, H.1
Da Mao L, Y.2
Li, Y.3
Li, D.4
Xu, Z.5
-
14
-
-
80052045217
-
Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment
-
Li J, Liu Y,Wang Z, Liu K,Wang Y, Liu J et al. Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment. J Virol 2011; 85: 6319-6333.
-
(2011)
J Virol
, vol.85
, pp. 6319-6333
-
-
Li, J.1
Liu Ywang, Z.2
Liu Kwang, Y.3
Liu, J.4
-
15
-
-
77749292148
-
The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication
-
Sir D, Tian Y, Chen WL, Ann DK, Yen TS, Ou JH. The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication. Proc Natl Acad Sci USA 2010; 107: 4383-4388.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4383-4388
-
-
Sir, D.1
Tian, Y.2
Chen, W.L.3
Ann, D.K.4
Yen, T.S.5
Ou, J.H.6
-
16
-
-
84855824374
-
Autophagy required for hepatitis B virus replication in transgenic mice
-
Tian Y, Sir D, Kuo CF, Ann DK, Ou JH. Autophagy required for hepatitis B virus replication in transgenic mice. J Virol 2011; 85: 13453-13456.
-
(2011)
J Virol
, vol.85
, pp. 13453-13456
-
-
Tian, Y.1
Sir, D.2
Kuo, C.F.3
Ann, D.K.4
Ou, J.H.5
-
17
-
-
84931029546
-
Green tea compounds in breast cancer prevention and treatment
-
Li MJ, Yin YC, Wang J, Jiang YF. Green tea compounds in breast cancer prevention and treatment. World J Clin Oncol 2014; 5: 520-528.
-
(2014)
World J Clin Oncol
, vol.5
, pp. 520-528
-
-
Li, M.J.1
Yin, Y.C.2
Wang, J.3
Jiang, Y.F.4
-
18
-
-
84874284327
-
Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea
-
Steinmann J, Buer J, Pietschmann T, Steinmann E. Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br J Pharmacol 2013; 168: 1059-1073.
-
(2013)
Br J Pharmacol
, vol.168
, pp. 1059-1073
-
-
Steinmann, J.1
Buer, J.2
Pietschmann, T.3
Steinmann, E.4
-
19
-
-
34347381789
-
Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection
-
Tipoe GL, Leung TM, Hung MW, Fung ML. Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc Hematol Disord Drug Targets 2007; 7: 135-144.
-
(2007)
Cardiovasc Hematol Disord Drug Targets
, vol.7
, pp. 135-144
-
-
Tipoe, G.L.1
Leung, T.M.2
Hung, M.W.3
Fung, M.L.4
-
20
-
-
84987846198
-
The antimicrobial possibilities of green tea
-
Reygaert WC. The antimicrobial possibilities of green tea. Front Microbiol 2014; 5: 434.
-
(2014)
Front Microbiol
, vol.5
, pp. 434
-
-
Reygaert, W.C.1
-
21
-
-
80155153050
-
Epigallocatechin gallate inhibits the HIV reverse transcription step
-
Li S, Hattori T, Kodama EN. Epigallocatechin gallate inhibits the HIV reverse transcription step. Antivir Chem Chemother 2011; 21: 239-243.
-
(2011)
Antivir Chem Chemother
, vol.21
, pp. 239-243
-
-
Li, S.1
Hattori, T.2
Kodama, E.N.3
-
22
-
-
33845222645
-
Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy
-
Williamson MP, McCormick TG, Nance CL, Shearer WT. Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. J Allergy Clin Immunol 2006; 118: 1369-1374.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 1369-1374
-
-
Williamson, M.P.1
McCormick, T.G.2
Nance, C.L.3
Shearer, W.T.4
-
23
-
-
58349094740
-
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
-
Choi KC, Jung MG, Lee YH, Yoon JC, Kwon SH, Kang HB et al. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res 2009; 69: 583-592.
-
(2009)
Cancer Res
, vol.69
, pp. 583-592
-
-
Choi, K.C.1
Jung, M.G.2
Lee, Y.H.3
Yoon, J.C.4
Kwon, S.H.5
Kang, H.B.6
-
24
-
-
84857376631
-
(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry
-
Calland N, Albecka A, Belouzard S, Wychowski C, Duverlie G, Descamps V et al. (-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. Hepatology 2012; 55: 720-729.
-
(2012)
Hepatology
, vol.55
, pp. 720-729
-
-
Calland, N.1
Albecka, A.2
Belouzard, S.3
Wychowski, C.4
Duverlie, G.5
Descamps, V.6
-
25
-
-
82455162669
-
The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry
-
Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J et al. The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry. Hepatology 2011; 54: 1947-1955.
-
(2011)
Hepatology
, vol.54
, pp. 1947-1955
-
-
Ciesek, S.1
Von Hahn, T.2
Colpitts, C.C.3
Schang, L.M.4
Friesland, M.5
Steinmann, J.6
-
26
-
-
84874093548
-
EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagy
-
Satoh M, Takemura Y, Hamada H, Sekido Y, Kubota S. EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagy. Cancer Cell Int 2013; 13: 19.
-
(2013)
Cancer Cell Int
, vol.13
, pp. 19
-
-
Satoh, M.1
Takemura, Y.2
Hamada, H.3
Sekido, Y.4
Kubota, S.5
-
27
-
-
84881233274
-
Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation
-
Kim HS, Montana V, Jang HJ, Parpura V, Kim JA. Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: a potential role for reducing lipid accumulation. J Biol Chem 2013; 288: 22693-22705.
-
(2013)
J Biol Chem
, vol.288
, pp. 22693-22705
-
-
Kim, H.S.1
Montana, V.2
Jang, H.J.3
Parpura, V.4
Kim, J.A.5
-
28
-
-
84900344034
-
Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance
-
Zhou J, Farah BL, Sinha RA, Wu Y, Singh BK, Bay BH et al. Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance. PLoS One 2014; 9: e87161.
-
(2014)
PLoS One
, vol.9
, pp. e87161
-
-
Zhou, J.1
Farah, B.L.2
Sinha, R.A.3
Wu, Y.4
Singh, B.K.5
Bay, B.H.6
-
29
-
-
84904556303
-
Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells
-
Chen L, Ye HL, Zhang G, Yao WM, Chen XZ, Zhang FC et al. Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells. PLoS One 2014; 9: e85771.
-
(2014)
PLoS One
, vol.9
, pp. e85771
-
-
Chen, L.1
Ye, H.L.2
Zhang, G.3
Yao, W.M.4
Chen, X.Z.5
Zhang, F.C.6
-
30
-
-
84883285744
-
Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB lightinduced retinal damage
-
Li CP, Yao J, Tao ZF, Li XM, Jiang Q, Yan B. Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB lightinduced retinal damage. Biochem Biophys Res Commun 2013; 438: 739-745.
-
(2013)
Biochem Biophys Res Commun
, vol.438
, pp. 739-745
-
-
Li, C.P.1
Yao, J.2
Tao, Z.F.3
Li, X.M.4
Jiang, Q.5
Yan, B.6
-
31
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8: 445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
-
33
-
-
84901062946
-
Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
-
González-Rodríguez A, Mayoral R, Agra N, Valdecantos MP, Pardo V, Miquilena-Colina ME et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis 2014; 5: e1179.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1179
-
-
González-Rodríguez, A.1
Mayoral, R.2
Agra, N.3
Valdecantos, M.P.4
Pardo, V.5
Miquilena-Colina, M.E.6
-
34
-
-
84879904303
-
Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux
-
Sreelatha A, Bennett TL, Zheng H, Jiang QX, Orth K, Starai VJ. Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux. Proc Natl Acad Sci USA 2013; 110: 11559-11564.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 11559-11564
-
-
Sreelatha, A.1
Bennett, T.L.2
Zheng, H.3
Jiang, Q.X.4
Orth, K.5
Starai, V.J.6
-
35
-
-
79551553480
-
Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
-
Ni HM, Bockus A, Wozniak AL, Jones K, Weinman S, Yin XM et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 2011; 7: 188-204.
-
(2011)
Autophagy
, vol.7
, pp. 188-204
-
-
Ni, H.M.1
Bockus, A.2
Wozniak, A.L.3
Jones, K.4
Weinman, S.5
Yin, X.M.6
-
36
-
-
84857260144
-
Lysosomal acidification mechanisms
-
Mindell JA. Lysosomal acidification mechanisms. Annu Rev Physiol 2012; 74: 69-86.
-
(2012)
Annu Rev Physiol
, vol.74
, pp. 69-86
-
-
Mindell, J.A.1
-
37
-
-
84861556595
-
Replication of hepatitis C virus RNA on autophagosomal membranes
-
Sir D, Kuo CF, Tian Y, Liu HM, Huang EJ, Jung JU et al. Replication of hepatitis C virus RNA on autophagosomal membranes. J Biol Chem 2012; 287: 18036-18043.
-
(2012)
J Biol Chem
, vol.287
, pp. 18036-18043
-
-
Sir, D.1
Kuo, C.F.2
Tian, Y.3
Liu, H.M.4
Huang, E.J.5
Jung, J.U.6
-
38
-
-
50949133741
-
Autophagosome supports coxsackievirus B3 replication in host cells
-
Wong J, Zhang J, Si X, Gao G, Mao I, McManus BM et al. Autophagosome supports coxsackievirus B3 replication in host cells. J Virol 2008; 82: 9143-9153.
-
(2008)
J Virol
, vol.82
, pp. 9143-9153
-
-
Wong, J.1
Zhang, J.2
Si, X.3
Gao, G.4
Mao, I.5
McManus, B.M.6
-
39
-
-
77954480306
-
Enhancement of autophagy during lytic replication by the Kaposi's sarcoma-associated herpesvirus replication and transcription activator
-
Wen HJ, Yang Z, Zhou Y, Wood C. Enhancement of autophagy during lytic replication by the Kaposi's sarcoma-associated herpesvirus replication and transcription activator. J Virol 2010; 84: 7448-7458.
-
(2010)
J Virol
, vol.84
, pp. 7448-7458
-
-
Wen, H.J.1
Yang, Z.2
Zhou, Y.3
Wood, C.4
-
40
-
-
84880919517
-
Autophagy and viruses: Adversaries or allies?
-
Dong X, Levine B. Autophagy and viruses: adversaries or allies? J Innate Immun 2013; 5: 480-493.
-
(2013)
J Innate Immun
, vol.5
, pp. 480-493
-
-
Dong, X.1
Levine, B.2
-
41
-
-
80052251448
-
Autophagy in the control and pathogenesis of viral infection
-
Yordy B, Iwasaki A. Autophagy in the control and pathogenesis of viral infection. Curr Opin Virol 2011; 1: 196-203.
-
(2011)
Curr Opin Virol
, vol.1
, pp. 196-203
-
-
Yordy, B.1
Iwasaki, A.2
-
42
-
-
84856020006
-
Manipulation or capitulation. Virus interactions with autophagy
-
Jordan TX, Randall G. Manipulation or capitulation. virus interactions with autophagy. Microbes Infect 2012; 14: 126-139.
-
(2012)
Microbes Infect
, vol.14
, pp. 126-139
-
-
Jordan, T.X.1
Randall, G.2
-
43
-
-
84908001653
-
Epstein-Barr virus blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replication
-
Granato M, Santarelli R, Farina A, Gonnella R, Lotti LV, Faggioni A et al. Epstein-barr virus blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replication. J Virol 2014; 88: 12715-12726.
-
(2014)
J Virol
, vol.88
, pp. 12715-12726
-
-
Granato, M.1
Santarelli, R.2
Farina, A.3
Gonnella, R.4
Lotti, L.V.5
Faggioni, A.6
-
44
-
-
41049085144
-
Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro
-
Xu J, Wang J, Deng F, Hu Z, Wang H. Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro. Antiviral Res 2008; 78: 242-249.
-
(2008)
Antiviral Res
, vol.78
, pp. 242-249
-
-
Xu, J.1
Wang, J.2
Deng, F.3
Hu, Z.4
Wang, H.5
-
45
-
-
79955942412
-
Epigallocatechin gallate inhibits HBV DNA synthesis in a viral replication - Inducible cell line
-
He W, Li LX, Liao QJ, Liu CL, Chen XL. Epigallocatechin gallate inhibits HBV DNA synthesis in a viral replication - inducible cell line. World J Gastroenterol 2011; 17: 1507-1514.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 1507-1514
-
-
He, W.1
Li, L.X.2
Liao, Q.J.3
Liu, C.L.4
Chen, X.L.5
-
46
-
-
84896929395
-
Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation
-
Liu B, Fang M, Hu Y, Huang B, Li N, Chang C, Huang R et al. Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation. Autophagy 2014; 10: 416-430.
-
(2014)
Autophagy
, vol.10
, pp. 416-430
-
-
Liu, B.1
Fang, M.2
Hu, Y.3
Huang, B.4
Li, N.5
Chang, C.6
Huang, R.7
-
47
-
-
84879614361
-
Inhibition of histone deacetylase activity suppresses IFN-gamma induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1
-
Gao B, Wang Y, Xu W, Li S, Li Q, Xiong S. Inhibition of histone deacetylase activity suppresses IFN-gamma induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1. J Immunol 2013; 191: 464-471.
-
(2013)
J Immunol
, vol.191
, pp. 464-471
-
-
Gao, B.1
Wang, Y.2
Xu, W.3
Li, S.4
Li, Q.5
Xiong, S.6
-
48
-
-
84881530009
-
P300, but not PCAF, collaborates with IRF-1 in stimulating TRIM22 expression independently of its histone acetyltransferase activity
-
Gao B, XuW, Zhong L, Zhang Q, Su Y, Xiong S. p300, but not PCAF, collaborates with IRF-1 in stimulating TRIM22 expression independently of its histone acetyltransferase activity. Eur J Immunol 2013; 43: 2174-2184.
-
(2013)
Eur J Immunol
, vol.43
, pp. 2174-2184
-
-
Gao, B.1
Xu, W.2
Zhong, L.3
Zhang, Q.4
Su, Y.5
Xiong, S.6
-
49
-
-
68949189335
-
Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain
-
Gao B, Duan Z, Xu W, Xiong S. Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain. Hepatology 2009; 50: 424-433.
-
(2009)
Hepatology
, vol.50
, pp. 424-433
-
-
Gao, B.1
Duan, Z.2
Xu, W.3
Xiong, S.4
-
50
-
-
1342268265
-
Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide
-
Kanzawa T, Bedwell J, Kondo Y, Kondo S, Germano IM. Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide. J Neurosurg 2003; 99: 1047-1052.
-
(2003)
J Neurosurg
, vol.99
, pp. 1047-1052
-
-
Kanzawa, T.1
Bedwell, J.2
Kondo, Y.3
Kondo, S.4
Germano, I.M.5
|