A Method for the Acute and Rapid Degradation of Endogenous Proteins

Cell

Volumn 171, Issue 7, 2017, Pages 1692-1706.e18

  Clift, Dean ^a   McEwan, William A ^a   Labzin, Larisa I ^a   Konieczny, Vera ^b   Mogessie, Binyam ^b   James, Leo C ^a   Schuh, Melina ^a,b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

antibodies; cell division; CRISPR Cas9; macrophages; meiosis; oocytes; primary cells; protein degradation; protein knockdown; RNAi

Indexed keywords

MESSENGER RNA; PROTEIN; ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE TARGETING; GENOME; HUMAN; HUMAN CELL; MALE; MAMMAL CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; ANIMAL; BIOCHEMISTRY; CHEMISTRY; PROCEDURES; PROTEIN TRANSPORT;

ANIMALS; ANTIBODIES; BIOCHEMISTRY; PROTEIN TRANSPORT; PROTEOLYSIS;

EID: 85034414408     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.10.033     Document Type: Article

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