CD38-NAD + Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

Cell Metabolism

Volumn 27, Issue 1, 2018, Pages 85-100.e8

  Chatterjee, Shilpak ^a   Daenthanasanmak, Anusara ^a   Chakraborty, Paramita ^a   Wyatt, Megan W ^a   Dhar, Payal ^a   Selvam, Shanmugam Panneer ^a   Fu, Jianing ^a   Zhang, Jinyu ^a   Nguyen, Hung ^a   Kang, Inhong ^a   Toth, Kyle ^a   Al Homrani, Mazen ^a   Husain, Mahvash ^a   Beeson, Gyda ^b   Ball, Lauren ^b   Helke, Kristi ^a   Husain, Shahid ^a   Garrett Mayer, Elizabeth ^a   Hardiman, Gary ^b   Mehrotra, Meenal ^a   Nishimura, Michael I ^c   Beeson, Craig C ^b   Bupp, Melanie Gubbels ^d   Wu, Jennifer ^a   Ogretmen, Besim ^a   Paulos, Chrystal M ^a   Rathmell, Jeffery ^e   Yu, Xue Zhong ^a   Mehrotra, Shikhar ^a   more..

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d RANDOLPH MACON COLLEGE   (United States)

^e VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; AMINO ACID TRANSPORTER; BETA CATENIN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR3; COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 2; GAMMA INTERFERON; GFPT1 PROTEIN; GFPT2 PROTEIN; GLS1 PROTEIN; GLS2 PROTEIN; GRANZYME B; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 22; INTERLEUKIN 23 RECEPTOR; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; PPAT PROTEIN; PROTEIN BCL 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SIRTUIN 1; SLC1A5 PROTEIN; SLC3A2 PROTEIN; SLC7A5 PROTEIN; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; FOXO1 PROTEIN, MOUSE; GLUTAMINE;

ADOPTIVE IMMUNOTHERAPY; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER CONTROL; CANCER IMMUNOTHERAPY; CELL SURFACE; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; ENZYME ACTIVITY; ENZYME INHIBITION; EX VIVO STUDY; GENE EXPRESSION PROFILING; GLUTAMINOLYSIS; IMMUNOREGULATION; IN VIVO STUDY; LYMPHOCYTE FUNCTION; LYSIS; MALE; MELANOMA B16; METABOLOMICS; MITOCHONDRIAL DYNAMICS; MOUSE; MRNA EXPRESSION LEVEL; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; T CELL CULTURE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; TRANSCRIPTOMICS; TUMOR ASSOCIATED LEUKOCYTE; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; NEOPLASM; T LYMPHOCYTE;

ADP-RIBOSYL CYCLASE 1; ANIMALS; FORKHEAD BOX PROTEIN O1; GLUTAMINE; IMMUNOTHERAPY; MICE, INBRED C57BL; NAD; NEOPLASMS; SIRTUIN 1; T-LYMPHOCYTES; TH1 CELLS; TH17 CELLS;

EID: 85033367546     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2017.10.006     Document Type: Article

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