메뉴 건너뛰기




Volumn 74, Issue 21, 2014, Pages 6048-6059

Reducing CD73 expression by IL1β-programmed Th17 cells improves immunotherapeutic control of tumors

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE TRIPHOSPHATASE; CD39 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOTCH RECEPTOR; PYRUVIC ACID; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; APYRASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IL1B PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; NT5E PROTEIN, HUMAN;

EID: 84909606726     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1450     Document Type: Article
Times cited : (50)

References (50)
  • 1
    • 84859153479 scopus 로고    scopus 로고
    • Raising the bar: The curative potential of human cancer immunotherapy
    • Rosenberg SA. Raising the bar: the curative potential of human cancer immunotherapy. Sci Transl Med 2012;4:127ps8.
    • (2012) Sci Transl Med , vol.4 , pp. 127ps8
    • Rosenberg, S.A.1
  • 2
    • 80155127321 scopus 로고    scopus 로고
    • Prospects for TIM3-targeted antitumor immunotherapy
    • Ngiow SF, Teng MW, Smyth MJ. Prospects for TIM3-targeted antitumor immunotherapy. Cancer Res 2011;71:6567-71.
    • (2011) Cancer Res , vol.71 , pp. 6567-6571
    • Ngiow, S.F.1    Teng, M.W.2    Smyth, M.J.3
  • 3
    • 66849135251 scopus 로고    scopus 로고
    • Cancer immunotherapy: Costimulatory agonists and co-inhibitory antagonists
    • Peggs KS, Quezada SA, Allison JP. Cancer immunotherapy: costimulatory agonists and co-inhibitory antagonists. Clin Exp Immunol 2009;157:9-19.
    • (2009) Clin Exp Immunol , vol.157 , pp. 9-19
    • Peggs, K.S.1    Quezada, S.A.2    Allison, J.P.3
  • 5
    • 47649122633 scopus 로고    scopus 로고
    • Tumor-specific Th17-polarized cells eradicate large established melanoma
    • Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 2008;112:362-73.
    • (2008) Blood , vol.112 , pp. 362-373
    • Muranski, P.1    Boni, A.2    Antony, P.A.3    Cassard, L.4    Irvine, K.R.5    Kaiser, A.6
  • 6
    • 84868611628 scopus 로고    scopus 로고
    • Th9 cells promote antitumor immune responses in vivo
    • Lu Y, Hong S, Li H, Park J, Hong B, Wang L, et al. Th9 cells promote antitumor immune responses in vivo. J Clin Invest 2012;122: 4160-71.
    • (2012) J Clin Invest , vol.122 , pp. 4160-4171
    • Lu, Y.1    Hong, S.2    Li, H.3    Park, J.4    Hong, B.5    Wang, L.6
  • 7
    • 84883863501 scopus 로고    scopus 로고
    • Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
    • Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, Ha TT, et al. Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med 2013; 5:200ra116.
    • (2013) Sci Transl Med , vol.5 , pp. 200ra116
    • Spranger, S.1    Spaapen, R.M.2    Zha, Y.3    Williams, J.4    Meng, Y.5    Ha, T.T.6
  • 8
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009;114:1141-9.
    • (2009) Blood , vol.114 , pp. 1141-1149
    • Kryczek, I.1    Banerjee, M.2    Cheng, P.3    Vatan, L.4    Szeliga, W.5    Wei, S.6
  • 9
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009;206:1457-64.
    • (2009) J Exp Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 12
    • 70349229827 scopus 로고    scopus 로고
    • Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death
    • YuY, Iclozan C,Yamazaki T,Yang X,Anasetti C,Dong C, et al.Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. Blood 2009;114:1026-8.
    • (2009) Blood , vol.114 , pp. 1026-1028
    • Yu, Y.1    Iclozan, C.2    Yamazaki, T.3    Yang, X.4    Anasetti, C.5    Dong, C.6
  • 13
    • 77951643783 scopus 로고    scopus 로고
    • FoxP3+RORgammat +T helper intermediates display suppressive function against autoimmune diabetes
    • Tartar DM, VanMorlan AM, Wan X, Guloglu FB, Jain R, Haymaker CL, et al. FoxP3+RORgammat +T helper intermediates display suppressive function against autoimmune diabetes. J Immunol 2010; 184:3377-85.
    • (2010) J Immunol , vol.184 , pp. 3377-3385
    • Tartar, D.M.1    Vanmorlan, A.M.2    Wan, X.3    Guloglu, F.B.4    Jain, R.5    Haymaker, C.L.6
  • 14
    • 84864800623 scopus 로고    scopus 로고
    • A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice
    • Mehrotra S, Al-Khami AA, Klarquist J, Husain S, Naga O, Eby JM, et al. A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice. J Immunol 2012; 189:1627-38.
    • (2012) J Immunol , vol.189 , pp. 1627-1638
    • Mehrotra, S.1    Al-Khami, A.A.2    Klarquist, J.3    Husain, S.4    Naga, O.5    Eby, J.M.6
  • 16
    • 40649083487 scopus 로고    scopus 로고
    • Advances in measuring cellular bioenergetics using extracellular flux
    • Ferrick DA, Neilson A, Beeson C. Advances in measuring cellular bioenergetics using extracellular flux. Drug Discov Today 2008; 13:268-74.
    • (2008) Drug Discov Today , vol.13 , pp. 268-274
    • Ferrick, D.A.1    Neilson, A.2    Beeson, C.3
  • 17
    • 50249085890 scopus 로고    scopus 로고
    • Increased level of extracellular ATP at tumor sites: In vivo imaging with plasma membrane luciferase
    • Pellegatti P, Raffaghello L, Bianchi G, Piccardi F, Pistoia V, Di Virgilio F. Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase. PLoS ONE 2008;3:e2599.
    • (2008) PLoS ONE , vol.3 , pp. e2599
    • Pellegatti, P.1    Raffaghello, L.2    Bianchi, G.3    Piccardi, F.4    Pistoia, V.5    Di Virgilio, F.6
  • 18
    • 84869078806 scopus 로고    scopus 로고
    • Production of adenosine by ectonucleotidases: A key factor in tumor immunoescape
    • Ghiringhelli F, Bruchard M, Chalmin F, Rebe C. Production of adenosine by ectonucleotidases: a key factor in tumor immunoescape. J Biomed Biotechnol 2012;2012:473712.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 473712
    • Ghiringhelli, F.1    Bruchard, M.2    Chalmin, F.3    Rebe, C.4
  • 19
    • 84858795377 scopus 로고    scopus 로고
    • Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression
    • Chalmin F, Mignot G, Bruchard M, Chevriaux A, Vegran F, Hichami A, et al. Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity 2012;36:362-73.
    • (2012) Immunity , vol.36 , pp. 362-373
    • Chalmin, F.1    Mignot, G.2    Bruchard, M.3    Chevriaux, A.4    Vegran, F.5    Hichami, A.6
  • 21
    • 84862067258 scopus 로고    scopus 로고
    • Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26)
    • Bengsch B, Seigel B, Flecken T, Wolanski J, Blum HE, Thimme R. Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26). J Immunol 2012;188:5438-47.
    • (2012) J Immunol , vol.188 , pp. 5438-5447
    • Bengsch, B.1    Seigel, B.2    Flecken, T.3    Wolanski, J.4    Blum, H.E.5    Thimme, R.6
  • 22
    • 60749107176 scopus 로고    scopus 로고
    • The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
    • McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol 2009;10:314-24.
    • (2009) Nat Immunol , vol.10 , pp. 314-324
    • McGeachy, M.J.1    Chen, Y.2    Tato, C.M.3    Laurence, A.4    Joyce-Shaikh, B.5    Blumenschein, W.M.6
  • 23
    • 77950548359 scopus 로고    scopus 로고
    • Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis
    • Mus AM, Cornelissen F, Asmawidjaja PS, van Hamburg JP, Boon L, Hendriks RW, et al. Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis. Arthritis Rheum 2010;62:1043-50.
    • (2010) Arthritis Rheum , vol.62 , pp. 1043-1050
    • Mus, A.M.1    Cornelissen, F.2    Asmawidjaja, P.S.3    Van Hamburg, J.P.4    Boon, L.5    Hendriks, R.W.6
  • 24
    • 84876808514 scopus 로고    scopus 로고
    • Cutting edge: The pathogenicity of IFN-gamma-producing Th17 cells is independent of T-bet
    • Duhen R, Glatigny S, Arbelaez CA, Blair TC, Oukka M, Bettelli E. Cutting edge: the pathogenicity of IFN-gamma-producing Th17 cells is independent of T-bet. J Immunol 2013;190:4478-82.
    • (2013) J Immunol , vol.190 , pp. 4478-4482
    • Duhen, R.1    Glatigny, S.2    Arbelaez, C.A.3    Blair, T.C.4    Oukka, M.5    Bettelli, E.6
  • 26
    • 84892534048 scopus 로고    scopus 로고
    • IL-12 and type i interferon prolong the division of activated CD8 T cells by maintaining highaffinity IL-2 signaling in vivo
    • Starbeck-Miller GR, Xue HH, Harty JT. IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining highaffinity IL-2 signaling in vivo. J Exp Med 2014;211:105-20.
    • (2014) J Exp Med , vol.211 , pp. 105-120
    • Starbeck-Miller, G.R.1    Xue, H.H.2    Harty, J.T.3
  • 27
    • 84876758617 scopus 로고    scopus 로고
    • Metabolic pathways in immune cell activation and quiescence
    • Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity 2013;38:633-43.
    • (2013) Immunity , vol.38 , pp. 633-643
    • Pearce, E.L.1    Pearce, E.J.2
  • 28
    • 84874242919 scopus 로고    scopus 로고
    • Mitochondria are required for antigen-specific T-cell activation through reactive oxygen species signaling
    • Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, et al. Mitochondria are required for antigen-specific T-cell activation through reactive oxygen species signaling. Immunity 2013;38:225-36.
    • (2013) Immunity , vol.38 , pp. 225-236
    • Sena, L.A.1    Li, S.2    Jairaman, A.3    Prakriya, M.4    Ezponda, T.5    Hildeman, D.A.6
  • 29
  • 30
    • 17044422629 scopus 로고    scopus 로고
    • Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells
    • Cham CM, Gajewski TF. Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells. J Immunol 2005;174:4670-7.
    • (2005) J Immunol , vol.174 , pp. 4670-4677
    • Cham, C.M.1    Gajewski, T.F.2
  • 31
    • 0034669954 scopus 로고    scopus 로고
    • Cutting edge: Off cycling of TNF production by antigen-specific CD8+ T cells is antigen independent
    • Badovinac VP, Corbin GA, Harty JT. Cutting edge: OFF cycling of TNF production by antigen-specific CD8+ T cells is antigen independent. J Immunol 2000;165:5387-91.
    • (2000) J Immunol , vol.165 , pp. 5387-5391
    • Badovinac, V.P.1    Corbin, G.A.2    Harty, J.T.3
  • 32
    • 11844252114 scopus 로고    scopus 로고
    • T cells undergo rapid ON/OFF but not ON/OFF/ on cycling of cytokine production in response to antigen
    • Corbin GA, Harty JT. T cells undergo rapid ON/OFF but not ON/OFF/ ON cycling of cytokine production in response to antigen. J Immunol 2005;174:718-26.
    • (2005) J Immunol , vol.174 , pp. 718-726
    • Corbin, G.A.1    Harty, J.T.2
  • 33
    • 61849149315 scopus 로고    scopus 로고
    • Is TGF-beta a stemness regulator?
    • Karlsson S. Is TGF-beta a stemness regulator? Blood 2009;113:1208.
    • (2009) Blood , vol.113 , pp. 1208
    • Karlsson, S.1
  • 34
    • 84885055994 scopus 로고    scopus 로고
    • Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
    • Sukumar M, Liu J, Ji Y, Subramanian M, Crompton JG, Yu Z, et al. Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J Clin Invest 2013;123:4479-88.
    • (2013) J Clin Invest , vol.123 , pp. 4479-4488
    • Sukumar, M.1    Liu, J.2    Ji, Y.3    Subramanian, M.4    Crompton, J.G.5    Yu, Z.6
  • 37
    • 84893832325 scopus 로고    scopus 로고
    • Tumor-specific IL-9-producing CD8+Tc9 cells are superior effector than type-I cytotoxic Tc1 cells for adoptive immunotherapy of cancers
    • Lu Y, Hong B, Li H, Zheng Y, Zhang M,WangS, et al. Tumor-specific IL-9-producing CD8+Tc9 cells are superior effector than type-I cytotoxic Tc1 cells for adoptive immunotherapy of cancers. Proc Natl Acad Sci U S A 2014;111:2265-70.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 2265-2270
    • Lu, Y.1    Hong, B.2    Li, H.3    Zheng, Y.4    Zhang, M.5    Wang, S.6
  • 40
    • 84355162720 scopus 로고    scopus 로고
    • Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment
    • Hu W, Troutman TD, Edukulla R, Pasare C. Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment. Immunity 2011;35:1010-22.
    • (2011) Immunity , vol.35 , pp. 1010-1022
    • Hu, W.1    Troutman, T.D.2    Edukulla, R.3    Pasare, C.4
  • 41
    • 77955750932 scopus 로고    scopus 로고
    • CD73: A novel target for cancer immunotherapy
    • Zhang B. CD73: a novel target for cancer immunotherapy. Cancer Res 2010;70:6407-11.
    • (2010) Cancer Res , vol.70 , pp. 6407-6411
    • Zhang, B.1
  • 42
    • 84886432843 scopus 로고    scopus 로고
    • TargetingCD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs
    • Allard B,PommeyS, Smyth MJ, Stagg J. TargetingCD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs. Clin Cancer Res 2013;19:5626-35.
    • (2013) Clin Cancer Res , vol.19 , pp. 5626-5635
    • Allard, B.1    Pommey, S.2    Smyth, M.J.3    Stagg, J.4
  • 43
    • 84867351931 scopus 로고    scopus 로고
    • Opportunities and challenges for anti-CD73 cancer therapy
    • Zhang B. Opportunities and challenges for anti-CD73 cancer therapy. Immunotherapy 2012;4:861-5.
    • (2012) Immunotherapy , vol.4 , pp. 861-865
    • Zhang, B.1
  • 45
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007; 204:1257-65.
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6
  • 46
    • 84877627620 scopus 로고    scopus 로고
    • IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells
    • Ben-Sasson SZ, Hogg A, Hu-Li J, Wingfield P, Chen X, Crank M, et al. IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells. J Exp Med 2013; 210:491-502.
    • (2013) J Exp Med , vol.210 , pp. 491-502
    • Ben-Sasson, S.Z.1    Hogg, A.2    Hu-Li, J.3    Wingfield, P.4    Chen, X.5    Crank, M.6
  • 48
    • 78650178184 scopus 로고    scopus 로고
    • Th1 versus Th17: Are T-cell cytokines relevant in multiple sclerosis?
    • Lovett-Racke AE, Yang Y, Racke MK. Th1 versus Th17: are T-cell cytokines relevant in multiple sclerosis? Biochim Biophys Acta 2011;1812:246-51.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 246-251
    • Lovett-Racke, A.E.1    Yang, Y.2    Racke, M.K.3
  • 49
    • 85047685683 scopus 로고    scopus 로고
    • Ecto-50-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia
    • Synnestvedt K, Furuta GT, Comerford KM, Louis N, Karhausen J, Eltzschig HK, et al. Ecto-50-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 2002;110:993-1002.
    • (2002) J Clin Invest , vol.110 , pp. 993-1002
    • Synnestvedt, K.1    Furuta, G.T.2    Comerford, K.M.3    Louis, N.4    Karhausen, J.5    Eltzschig, H.K.6
  • 50
    • 84875590401 scopus 로고    scopus 로고
    • Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma
    • Lu XX, ChenYT, Feng B,MaoXB, Yu B, Chu XY. Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma. World J Gastroenterol 2013;19:1912-8.
    • (2013) World J Gastroenterol , vol.19 , pp. 1912-1918
    • Lu, X.X.1    Chen, Y.T.2    Feng, B.3    Mao, X.B.4    Yu, B.5    Chu, X.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.