CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

Cell Metabolism

Volumn 23, Issue 6, 2016, Pages 1127-1139

  Camacho Pereira, Juliana ^a,b   Tarragó, Mariana G ^a   Chini, Claudia C S ^a   Nin, Veronica ^a   Escande, Carlos ^a   Warner, Gina M ^a   Puranik, Amrutesh S ^a   Schoon, Renee A ^c   Reid, Joel M ^c   Galina, Antonio ^b   Chini, Eduardo N ^a  

^a MAYO CLINIC   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Mayo Clinic College of Medicine   (United States)

Author keywords

aging; CD38; glucose intolerance; mitochondrial function; NAD+

Indexed keywords

CD38 ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE NUCLEOSIDASE; NICOTINAMIDE NUCLEOTIDE; SIRTUIN 3; MESSENGER RNA; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE-BETA-RIBOSIDE;

AGING; ARTICLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME DEGRADATION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; METABOLIC DISORDER; METABOLISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANALOGS AND DERIVATIVES; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; LIPID DIET; MAMMAL; MITOCHONDRION; ULTRASTRUCTURE;

AGING; ANIMALS; ANTIGENS, CD38; DIET, HIGH-FAT; MAMMALS; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NAD; NAD+ NUCLEOSIDASE; NIACINAMIDE; ORGAN SPECIFICITY; RNA, MESSENGER; SIRTUIN 3;

EID: 84975472602     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.05.006     Document Type: Article

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